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1صورة
المؤلفون: Sydney Stanley, Xin Wang, Qingyun Liu, Young Yon Kwon, Abigail M. Frey, Nathan D. Hicks, Andrew J. Vickers, Sheng Hui, Sarah M. Fortune
مصطلحات موضوعية: Biochemistry, Microbiology, Genetics, Molecular Biology, Evolutionary Biology, Ecology, Cancer, Infectious Diseases, Computational Biology, Environmental Sciences not elsewhere classified, providing experimental evidence, div >< p, central carbon metabolism, 1 virulence system, mycobacterium tuberculosis <, discernible growth defect, dependent antibiotic susceptibility, mutations functionally increase, human host environment, global clinical isolates, lactate dehydrogenase reveals, assessing mtb genes, 13 sup, clinical isolates, vivo <, mtb growth, lactate dehydrogenase, intracellular environment, host pressure, genes involved
الإتاحة: https://doi.org/10.1371/journal.ppat.1012050.g001Test
https://figshare.com/articles/figure/Stepwise_evolution_of_LldD2_/25320174Test -
2صورة
المؤلفون: Sydney Stanley, Xin Wang, Qingyun Liu, Young Yon Kwon, Abigail M. Frey, Nathan D. Hicks, Andrew J. Vickers, Sheng Hui, Sarah M. Fortune
مصطلحات موضوعية: Biochemistry, Microbiology, Genetics, Molecular Biology, Evolutionary Biology, Ecology, Cancer, Infectious Diseases, Computational Biology, Environmental Sciences not elsewhere classified, providing experimental evidence, div >< p, central carbon metabolism, 1 virulence system, mycobacterium tuberculosis <, discernible growth defect, dependent antibiotic susceptibility, mutations functionally increase, human host environment, global clinical isolates, lactate dehydrogenase reveals, assessing mtb genes, 13 sup, clinical isolates, vivo <, mtb growth, lactate dehydrogenase, intracellular environment, host pressure, genes involved
الإتاحة: https://doi.org/10.1371/journal.ppat.1012050.g005Test
https://figshare.com/articles/figure/Lactate_and_i_lldD2_i_variants_remodel_the_Mtb_virulence_transcriptome_/25320186Test -
3صورة
المؤلفون: Sydney Stanley, Xin Wang, Qingyun Liu, Young Yon Kwon, Abigail M. Frey, Nathan D. Hicks, Andrew J. Vickers, Sheng Hui, Sarah M. Fortune
مصطلحات موضوعية: Biochemistry, Microbiology, Genetics, Molecular Biology, Evolutionary Biology, Ecology, Cancer, Infectious Diseases, Computational Biology, Environmental Sciences not elsewhere classified, providing experimental evidence, div >< p, central carbon metabolism, 1 virulence system, mycobacterium tuberculosis <, discernible growth defect, dependent antibiotic susceptibility, mutations functionally increase, human host environment, global clinical isolates, lactate dehydrogenase reveals, assessing mtb genes, 13 sup, clinical isolates, vivo <, mtb growth, lactate dehydrogenase, intracellular environment, host pressure, genes involved
الإتاحة: https://doi.org/10.1371/journal.ppat.1012050.g004Test
https://figshare.com/articles/figure/_i_lldD2_i_homoplastic_mutations_modulate_gene_and_enzyme_activity_/25320183Test -
4صورة
المؤلفون: Sydney Stanley, Xin Wang, Qingyun Liu, Young Yon Kwon, Abigail M. Frey, Nathan D. Hicks, Andrew J. Vickers, Sheng Hui, Sarah M. Fortune
مصطلحات موضوعية: Biochemistry, Microbiology, Genetics, Molecular Biology, Evolutionary Biology, Ecology, Cancer, Infectious Diseases, Computational Biology, Environmental Sciences not elsewhere classified, providing experimental evidence, div >< p, central carbon metabolism, 1 virulence system, mycobacterium tuberculosis <, discernible growth defect, dependent antibiotic susceptibility, mutations functionally increase, human host environment, global clinical isolates, lactate dehydrogenase reveals, assessing mtb genes, 13 sup, clinical isolates, vivo <, mtb growth, lactate dehydrogenase, intracellular environment, host pressure, genes involved
الإتاحة: https://doi.org/10.1371/journal.ppat.1012050.g003Test
https://figshare.com/articles/figure/Ancestral_and_homoplastic_mutations_in_i_lldD2_i_augment_Mtb_fitness_in_lactate_/25320180Test -
5صورة
المؤلفون: Sydney Stanley, Xin Wang, Qingyun Liu, Young Yon Kwon, Abigail M. Frey, Nathan D. Hicks, Andrew J. Vickers, Sheng Hui, Sarah M. Fortune
مصطلحات موضوعية: Biochemistry, Microbiology, Genetics, Molecular Biology, Evolutionary Biology, Ecology, Cancer, Infectious Diseases, Computational Biology, Environmental Sciences not elsewhere classified, providing experimental evidence, div >< p, central carbon metabolism, 1 virulence system, mycobacterium tuberculosis <, discernible growth defect, dependent antibiotic susceptibility, mutations functionally increase, human host environment, global clinical isolates, lactate dehydrogenase reveals, assessing mtb genes, 13 sup, clinical isolates, vivo <, mtb growth, lactate dehydrogenase, intracellular environment, host pressure, genes involved
الإتاحة: https://doi.org/10.1371/journal.ppat.1012050.g002Test
https://figshare.com/articles/figure/Prevalence_of_various_LldD2_mutations_/25320177Test -
6صورة
مصطلحات موضوعية: Biochemistry, Genetics, Molecular Biology, Biotechnology, Ecology, Developmental Biology, Cancer, Inorganic Chemistry, Biological Sciences not elsewhere classified, whole animal level, specialized metabolic state, promoting juvenile development, one unique feature, fly life cycle, specific growth programs, promote rapid growth, larval metabolic program, larval development relies, drosophila melanogaster <, study glycolytic metabolism, enzyme promotes tissue, lactate dehydrogenase <, larval ldh activity, lactate dehydrogenase, growth phase, vivo <, ldh <, utilizes carbohydrates, studies validate, reagents demonstrate
الإتاحة: https://doi.org/10.1371/journal.pone.0287865.g001Test
https://figshare.com/articles/figure/Genetic_characterization_of_the_i_p_Ldh-GFP_i_transgene_/24938206Test -
7صورة
مصطلحات موضوعية: Biochemistry, Genetics, Molecular Biology, Biotechnology, Ecology, Developmental Biology, Cancer, Inorganic Chemistry, Biological Sciences not elsewhere classified, whole animal level, specialized metabolic state, promoting juvenile development, one unique feature, fly life cycle, specific growth programs, promote rapid growth, larval metabolic program, larval development relies, drosophila melanogaster <, study glycolytic metabolism, enzyme promotes tissue, lactate dehydrogenase <, larval ldh activity, lactate dehydrogenase, growth phase, vivo <, ldh <, utilizes carbohydrates, studies validate, reagents demonstrate
الإتاحة: https://doi.org/10.1371/journal.pone.0287865.g002Test
https://figshare.com/articles/figure/Characterization_of_i_Ldh_i_expression_in_the_central_nervous_system_/24938209Test -
8صورة
مصطلحات موضوعية: Biochemistry, Genetics, Molecular Biology, Biotechnology, Ecology, Developmental Biology, Cancer, Inorganic Chemistry, Biological Sciences not elsewhere classified, whole animal level, specialized metabolic state, promoting juvenile development, one unique feature, fly life cycle, specific growth programs, promote rapid growth, larval metabolic program, larval development relies, drosophila melanogaster <, study glycolytic metabolism, enzyme promotes tissue, lactate dehydrogenase <, larval ldh activity, lactate dehydrogenase, growth phase, vivo <, ldh <, utilizes carbohydrates, studies validate, reagents demonstrate
الإتاحة: https://doi.org/10.1371/journal.pone.0287865.g004Test
https://figshare.com/articles/figure/Characterization_of_i_Ldh_i_expression_in_the_intestine_and_Malpighian_tubules_/24938218Test -
9صورة
مصطلحات موضوعية: Biochemistry, Genetics, Molecular Biology, Biotechnology, Ecology, Developmental Biology, Cancer, Inorganic Chemistry, Biological Sciences not elsewhere classified, whole animal level, specialized metabolic state, promoting juvenile development, one unique feature, fly life cycle, specific growth programs, promote rapid growth, larval metabolic program, larval development relies, drosophila melanogaster <, study glycolytic metabolism, enzyme promotes tissue, lactate dehydrogenase <, larval ldh activity, lactate dehydrogenase, growth phase, vivo <, ldh <, utilizes carbohydrates, studies validate, reagents demonstrate
الإتاحة: https://doi.org/10.1371/journal.pone.0287865.g003Test
https://figshare.com/articles/figure/_i_Ldh_i_expression_in_ganglion_mother_cells_neurons_and_glia_/24938212Test -
10صورة
مصطلحات موضوعية: Biochemistry, Genetics, Molecular Biology, Biotechnology, Ecology, Developmental Biology, Cancer, Inorganic Chemistry, Biological Sciences not elsewhere classified, whole animal level, specialized metabolic state, promoting juvenile development, one unique feature, fly life cycle, specific growth programs, promote rapid growth, larval metabolic program, larval development relies, drosophila melanogaster <, study glycolytic metabolism, enzyme promotes tissue, lactate dehydrogenase <, larval ldh activity, lactate dehydrogenase, growth phase, vivo <, ldh <, utilizes carbohydrates, studies validate, reagents demonstrate
الإتاحة: https://doi.org/10.1371/journal.pone.0287865.g005Test
https://figshare.com/articles/figure/_i_Ldh_i_expression_pattern_in_the_fat_body_and_salivary_gland_/24938221Test