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1صورة
المؤلفون: Jakob L. Sprague, Tim B. Schille, Stefanie Allert, Verena Trümper, Adrian Lier, Peter Großmann, Emily L. Priest, Antzela Tsavou, Gianni Panagiotou, Julian R. Naglik, Duncan Wilson, Sascha Schäuble, Lydia Kasper, Bernhard Hube
مصطلحات موضوعية: Medicine, Microbiology, Cell Biology, Molecular Biology, Physiology, Ecology, Immunology, Cancer, Science Policy, Infectious Diseases, Environmental Sciences not elsewhere classified, Biological Sciences not elsewhere classified, Chemical Sciences not elsewhere classified, process remain unclear, microbial mechanisms behind, human mucosal surfaces, full virulence potential, frequently causes infections, div >< p, certain predisposing conditions, opportunistic fungal pathogen, peptide toxin candidalysin, intestinal epithelial barrier, fungal zinc acquisition, intestinal epithelial cells, mediated barrier protection, restrict fungal translocation, candida albicans <, iecs limits candidalysin, iecs counteract damage
الإتاحة: https://doi.org/10.1371/journal.ppat.1012031.s001Test
https://figshare.com/articles/figure/_i_C_i_i_albicans_i_zinc-associated_genes_are_more_highly_expressed_in_the_absence_of_IECs_/25328929Test -
2صورة
المؤلفون: Jakob L. Sprague, Tim B. Schille, Stefanie Allert, Verena Trümper, Adrian Lier, Peter Großmann, Emily L. Priest, Antzela Tsavou, Gianni Panagiotou, Julian R. Naglik, Duncan Wilson, Sascha Schäuble, Lydia Kasper, Bernhard Hube
مصطلحات موضوعية: Medicine, Microbiology, Cell Biology, Molecular Biology, Physiology, Ecology, Immunology, Cancer, Science Policy, Infectious Diseases, Environmental Sciences not elsewhere classified, Biological Sciences not elsewhere classified, Chemical Sciences not elsewhere classified, process remain unclear, microbial mechanisms behind, human mucosal surfaces, full virulence potential, frequently causes infections, div >< p, certain predisposing conditions, opportunistic fungal pathogen, peptide toxin candidalysin, intestinal epithelial barrier, fungal zinc acquisition, intestinal epithelial cells, mediated barrier protection, restrict fungal translocation, candida albicans <, iecs limits candidalysin, iecs counteract damage
الإتاحة: https://doi.org/10.1371/journal.ppat.1012031.s003Test
https://figshare.com/articles/figure/Loss_of_i_ECE1_i_has_no_effect_on_the_transcriptional_zinc_starvation_response_in_medium_only_/25328935Test -
3صورة
المؤلفون: Jakob L. Sprague, Tim B. Schille, Stefanie Allert, Verena Trümper, Adrian Lier, Peter Großmann, Emily L. Priest, Antzela Tsavou, Gianni Panagiotou, Julian R. Naglik, Duncan Wilson, Sascha Schäuble, Lydia Kasper, Bernhard Hube
مصطلحات موضوعية: Medicine, Microbiology, Cell Biology, Molecular Biology, Physiology, Ecology, Immunology, Cancer, Science Policy, Infectious Diseases, Environmental Sciences not elsewhere classified, Biological Sciences not elsewhere classified, Chemical Sciences not elsewhere classified, process remain unclear, microbial mechanisms behind, human mucosal surfaces, full virulence potential, frequently causes infections, div >< p, certain predisposing conditions, opportunistic fungal pathogen, peptide toxin candidalysin, intestinal epithelial barrier, fungal zinc acquisition, intestinal epithelial cells, mediated barrier protection, restrict fungal translocation, candida albicans <, iecs limits candidalysin, iecs counteract damage
الإتاحة: https://doi.org/10.1371/journal.ppat.1012031.s006Test
https://figshare.com/articles/figure/Western_blot_detection_of_immune_signaling_proteins_for_IECs_infected_with_WT_and_i_ece1_i_/25328944Test -
4صورة
المؤلفون: Jakob L. Sprague, Tim B. Schille, Stefanie Allert, Verena Trümper, Adrian Lier, Peter Großmann, Emily L. Priest, Antzela Tsavou, Gianni Panagiotou, Julian R. Naglik, Duncan Wilson, Sascha Schäuble, Lydia Kasper, Bernhard Hube
مصطلحات موضوعية: Medicine, Microbiology, Cell Biology, Molecular Biology, Physiology, Ecology, Immunology, Cancer, Science Policy, Infectious Diseases, Environmental Sciences not elsewhere classified, Biological Sciences not elsewhere classified, Chemical Sciences not elsewhere classified, process remain unclear, microbial mechanisms behind, human mucosal surfaces, full virulence potential, frequently causes infections, div >< p, certain predisposing conditions, opportunistic fungal pathogen, peptide toxin candidalysin, intestinal epithelial barrier, fungal zinc acquisition, intestinal epithelial cells, mediated barrier protection, restrict fungal translocation, candida albicans <, iecs limits candidalysin, iecs counteract damage
الإتاحة: https://doi.org/10.1371/journal.ppat.1012031.s002Test
https://figshare.com/articles/figure/Loss_of_i_ZRC1_i_significantly_impairs_hyphal_growth_in_i_C_i_i_albicans_i_/25328932Test -
5صورة
المؤلفون: Jakob L. Sprague, Tim B. Schille, Stefanie Allert, Verena Trümper, Adrian Lier, Peter Großmann, Emily L. Priest, Antzela Tsavou, Gianni Panagiotou, Julian R. Naglik, Duncan Wilson, Sascha Schäuble, Lydia Kasper, Bernhard Hube
مصطلحات موضوعية: Medicine, Microbiology, Cell Biology, Molecular Biology, Physiology, Ecology, Immunology, Cancer, Science Policy, Infectious Diseases, Environmental Sciences not elsewhere classified, Biological Sciences not elsewhere classified, Chemical Sciences not elsewhere classified, process remain unclear, microbial mechanisms behind, human mucosal surfaces, full virulence potential, frequently causes infections, div >< p, certain predisposing conditions, opportunistic fungal pathogen, peptide toxin candidalysin, intestinal epithelial barrier, fungal zinc acquisition, intestinal epithelial cells, mediated barrier protection, restrict fungal translocation, candida albicans <, iecs limits candidalysin, iecs counteract damage
الإتاحة: https://doi.org/10.1371/journal.ppat.1012031.s005Test
https://figshare.com/articles/figure/Transcriptional_response_of_IECs_to_infection_with_non-damaging_and_non-filamentous_i_C_i_i_albicans_i_/25328941Test -
6صورة
المؤلفون: Jakob L. Sprague, Tim B. Schille, Stefanie Allert, Verena Trümper, Adrian Lier, Peter Großmann, Emily L. Priest, Antzela Tsavou, Gianni Panagiotou, Julian R. Naglik, Duncan Wilson, Sascha Schäuble, Lydia Kasper, Bernhard Hube
مصطلحات موضوعية: Medicine, Microbiology, Cell Biology, Molecular Biology, Physiology, Ecology, Immunology, Cancer, Science Policy, Infectious Diseases, Environmental Sciences not elsewhere classified, Biological Sciences not elsewhere classified, Chemical Sciences not elsewhere classified, process remain unclear, microbial mechanisms behind, human mucosal surfaces, full virulence potential, frequently causes infections, div >< p, certain predisposing conditions, opportunistic fungal pathogen, peptide toxin candidalysin, intestinal epithelial barrier, fungal zinc acquisition, intestinal epithelial cells, mediated barrier protection, restrict fungal translocation, candida albicans <, iecs limits candidalysin, iecs counteract damage
الإتاحة: https://doi.org/10.1371/journal.ppat.1012031.g005Test
https://figshare.com/articles/figure/NF_B_activation_limits_i_ECE1_i_-dependent_damage_and_paracellular_translocation_/25328980Test -
7صورة
المؤلفون: Jakob L. Sprague, Tim B. Schille, Stefanie Allert, Verena Trümper, Adrian Lier, Peter Großmann, Emily L. Priest, Antzela Tsavou, Gianni Panagiotou, Julian R. Naglik, Duncan Wilson, Sascha Schäuble, Lydia Kasper, Bernhard Hube
مصطلحات موضوعية: Medicine, Microbiology, Cell Biology, Molecular Biology, Physiology, Ecology, Immunology, Cancer, Science Policy, Infectious Diseases, Environmental Sciences not elsewhere classified, Biological Sciences not elsewhere classified, Chemical Sciences not elsewhere classified, process remain unclear, microbial mechanisms behind, human mucosal surfaces, full virulence potential, frequently causes infections, div >< p, certain predisposing conditions, opportunistic fungal pathogen, peptide toxin candidalysin, intestinal epithelial barrier, fungal zinc acquisition, intestinal epithelial cells, mediated barrier protection, restrict fungal translocation, candida albicans <, iecs limits candidalysin, iecs counteract damage
الإتاحة: https://doi.org/10.1371/journal.ppat.1012031.s008Test
https://figshare.com/articles/figure/Treatment_of_IECs_with_another_NF_B_inhibitor_increases_host_cell_damage_loss_of_barrier_integrity_and_fungal_translocation_/25328950Test -
8صورة
المؤلفون: Jakob L. Sprague, Tim B. Schille, Stefanie Allert, Verena Trümper, Adrian Lier, Peter Großmann, Emily L. Priest, Antzela Tsavou, Gianni Panagiotou, Julian R. Naglik, Duncan Wilson, Sascha Schäuble, Lydia Kasper, Bernhard Hube
مصطلحات موضوعية: Medicine, Microbiology, Cell Biology, Molecular Biology, Physiology, Ecology, Immunology, Cancer, Science Policy, Infectious Diseases, Environmental Sciences not elsewhere classified, Biological Sciences not elsewhere classified, Chemical Sciences not elsewhere classified, process remain unclear, microbial mechanisms behind, human mucosal surfaces, full virulence potential, frequently causes infections, div >< p, certain predisposing conditions, opportunistic fungal pathogen, peptide toxin candidalysin, intestinal epithelial barrier, fungal zinc acquisition, intestinal epithelial cells, mediated barrier protection, restrict fungal translocation, candida albicans <, iecs limits candidalysin, iecs counteract damage
الإتاحة: https://doi.org/10.1371/journal.ppat.1012031.g002Test
https://figshare.com/articles/figure/Loss_of_zinc_acquisition_genes_in_i_C_i_i_albicans_i_decreases_damage_potential_by_impairing_growth_during_infection_of_IECs_/25328971Test -
9صورة
المؤلفون: Jakob L. Sprague, Tim B. Schille, Stefanie Allert, Verena Trümper, Adrian Lier, Peter Großmann, Emily L. Priest, Antzela Tsavou, Gianni Panagiotou, Julian R. Naglik, Duncan Wilson, Sascha Schäuble, Lydia Kasper, Bernhard Hube
مصطلحات موضوعية: Medicine, Microbiology, Cell Biology, Molecular Biology, Physiology, Ecology, Immunology, Cancer, Science Policy, Infectious Diseases, Environmental Sciences not elsewhere classified, Biological Sciences not elsewhere classified, Chemical Sciences not elsewhere classified, process remain unclear, microbial mechanisms behind, human mucosal surfaces, full virulence potential, frequently causes infections, div >< p, certain predisposing conditions, opportunistic fungal pathogen, peptide toxin candidalysin, intestinal epithelial barrier, fungal zinc acquisition, intestinal epithelial cells, mediated barrier protection, restrict fungal translocation, candida albicans <, iecs limits candidalysin, iecs counteract damage
الإتاحة: https://doi.org/10.1371/journal.ppat.1012031.s004Test
https://figshare.com/articles/figure/Addition_of_exogenous_zinc_alleviates_the_transcriptional_zinc_starvation_response_in_the_absence_of_i_ECE1_i_but_does_not_affect_host-cell_damage_fungal_translocation_or_fungal_load_/25328938Test -
10صورة
المؤلفون: Jakob L. Sprague, Tim B. Schille, Stefanie Allert, Verena Trümper, Adrian Lier, Peter Großmann, Emily L. Priest, Antzela Tsavou, Gianni Panagiotou, Julian R. Naglik, Duncan Wilson, Sascha Schäuble, Lydia Kasper, Bernhard Hube
مصطلحات موضوعية: Medicine, Microbiology, Cell Biology, Molecular Biology, Physiology, Ecology, Immunology, Cancer, Science Policy, Infectious Diseases, Environmental Sciences not elsewhere classified, Biological Sciences not elsewhere classified, Chemical Sciences not elsewhere classified, process remain unclear, microbial mechanisms behind, human mucosal surfaces, full virulence potential, frequently causes infections, div >< p, certain predisposing conditions, opportunistic fungal pathogen, peptide toxin candidalysin, intestinal epithelial barrier, fungal zinc acquisition, intestinal epithelial cells, mediated barrier protection, restrict fungal translocation, candida albicans <, iecs limits candidalysin, iecs counteract damage
الإتاحة: https://doi.org/10.1371/journal.ppat.1012031.s009Test
https://figshare.com/articles/figure/Treatment_with_a_pan-caspase_inhibitor_does_not_prevent_increased_virulence_upon_inhibition_of_NF_B_activation_/25328953Test