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11صورة
المؤلفون: Mubashir Aziz, Muhammad Sarfraz, Muhammad Khurrum Ibrahim, Syeda Abida Ejaz, Tasneem Zehra, Hanan A. Ogaly, Mosab Arafat, Fatimah A. M. Al-Zahrani, Chen Li
مصطلحات موضوعية: Biophysics, Biochemistry, Cell Biology, Genetics, Molecular Biology, Biotechnology, Cancer, Science Policy, Biological Sciences not elsewhere classified, Chemical Sciences not elsewhere classified, Information Systems not elsewhere classified, significant global cause, potent bioactive agents, particularly potent candidate, one strategic avenue, lactate dehydrogenase release, imparting significant insights, amidst ongoing efforts, employed computational techniques, computational analyses suggest, molecular dynamics simulations, including molecular docking, 3 activity assays, hydroxyacetyl )- 4, 6s )- 4, promising anticancer candidates, via caspase 3, study &# 8217, knowledge holds potential, demonstrated marked efficacy
الإتاحة: https://doi.org/10.1371/journal.pone.0292455.g007Test
https://figshare.com/articles/figure/Fig_7_-/24890233Test -
12صورة
المؤلفون: Mubashir Aziz, Muhammad Sarfraz, Muhammad Khurrum Ibrahim, Syeda Abida Ejaz, Tasneem Zehra, Hanan A. Ogaly, Mosab Arafat, Fatimah A. M. Al-Zahrani, Chen Li
مصطلحات موضوعية: Biophysics, Biochemistry, Cell Biology, Genetics, Molecular Biology, Biotechnology, Cancer, Science Policy, Biological Sciences not elsewhere classified, Chemical Sciences not elsewhere classified, Information Systems not elsewhere classified, significant global cause, potent bioactive agents, particularly potent candidate, one strategic avenue, lactate dehydrogenase release, imparting significant insights, amidst ongoing efforts, employed computational techniques, computational analyses suggest, molecular dynamics simulations, including molecular docking, 3 activity assays, hydroxyacetyl )- 4, 6s )- 4, promising anticancer candidates, via caspase 3, study &# 8217, knowledge holds potential, demonstrated marked efficacy
الإتاحة: https://doi.org/10.1371/journal.pone.0292455.g009Test
https://figshare.com/articles/figure/Putative_2D_and_3D_binding_mode_of_compound_A02_against_Caspase-3_/24890239Test -
13صورة
المؤلفون: Mubashir Aziz, Muhammad Sarfraz, Muhammad Khurrum Ibrahim, Syeda Abida Ejaz, Tasneem Zehra, Hanan A. Ogaly, Mosab Arafat, Fatimah A. M. Al-Zahrani, Chen Li
مصطلحات موضوعية: Biophysics, Biochemistry, Cell Biology, Genetics, Molecular Biology, Biotechnology, Cancer, Science Policy, Biological Sciences not elsewhere classified, Chemical Sciences not elsewhere classified, Information Systems not elsewhere classified, significant global cause, potent bioactive agents, particularly potent candidate, one strategic avenue, lactate dehydrogenase release, imparting significant insights, amidst ongoing efforts, employed computational techniques, computational analyses suggest, molecular dynamics simulations, including molecular docking, 3 activity assays, hydroxyacetyl )- 4, 6s )- 4, promising anticancer candidates, via caspase 3, study &# 8217, knowledge holds potential, demonstrated marked efficacy
العلاقة: https://figshare.com/articles/figure/Intercalation_of_DNA_groove_by_compound_A01_/24890254Test
الإتاحة: https://doi.org/10.1371/journal.pone.0292455.g014Test
https://figshare.com/articles/figure/Intercalation_of_DNA_groove_by_compound_A01_/24890254Test -
14صورة
المؤلفون: Mubashir Aziz, Muhammad Sarfraz, Muhammad Khurrum Ibrahim, Syeda Abida Ejaz, Tasneem Zehra, Hanan A. Ogaly, Mosab Arafat, Fatimah A. M. Al-Zahrani, Chen Li
مصطلحات موضوعية: Biophysics, Biochemistry, Cell Biology, Genetics, Molecular Biology, Biotechnology, Cancer, Science Policy, Biological Sciences not elsewhere classified, Chemical Sciences not elsewhere classified, Information Systems not elsewhere classified, significant global cause, potent bioactive agents, particularly potent candidate, one strategic avenue, lactate dehydrogenase release, imparting significant insights, amidst ongoing efforts, employed computational techniques, computational analyses suggest, molecular dynamics simulations, including molecular docking, 3 activity assays, hydroxyacetyl )- 4, 6s )- 4, promising anticancer candidates, via caspase 3, study &# 8217, knowledge holds potential, demonstrated marked efficacy
الإتاحة: https://doi.org/10.1371/journal.pone.0292455.g013Test
https://figshare.com/articles/figure/The_putative_binding_mode_of_compound_A02_against_P53_/24890251Test -
15صورة
المؤلفون: Mubashir Aziz, Muhammad Sarfraz, Muhammad Khurrum Ibrahim, Syeda Abida Ejaz, Tasneem Zehra, Hanan A. Ogaly, Mosab Arafat, Fatimah A. M. Al-Zahrani, Chen Li
مصطلحات موضوعية: Biophysics, Biochemistry, Cell Biology, Genetics, Molecular Biology, Biotechnology, Cancer, Science Policy, Biological Sciences not elsewhere classified, Chemical Sciences not elsewhere classified, Information Systems not elsewhere classified, significant global cause, potent bioactive agents, particularly potent candidate, one strategic avenue, lactate dehydrogenase release, imparting significant insights, amidst ongoing efforts, employed computational techniques, computational analyses suggest, molecular dynamics simulations, including molecular docking, 3 activity assays, hydroxyacetyl )- 4, 6s )- 4, promising anticancer candidates, via caspase 3, study &# 8217, knowledge holds potential, demonstrated marked efficacy
الإتاحة: https://doi.org/10.1371/journal.pone.0292455.g016Test
https://figshare.com/articles/figure/Representation_of_RMSD_pattern_for_apo_protein_NF-_B_red_colored_trajectory_and_liganded_protein_NF-_B_-A01_complex_represented_by_green_colored_trajectory_/24890260Test -
16صورة
المؤلفون: Mubashir Aziz, Muhammad Sarfraz, Muhammad Khurrum Ibrahim, Syeda Abida Ejaz, Tasneem Zehra, Hanan A. Ogaly, Mosab Arafat, Fatimah A. M. Al-Zahrani, Chen Li
مصطلحات موضوعية: Biophysics, Biochemistry, Cell Biology, Genetics, Molecular Biology, Biotechnology, Cancer, Science Policy, Biological Sciences not elsewhere classified, Chemical Sciences not elsewhere classified, Information Systems not elsewhere classified, significant global cause, potent bioactive agents, particularly potent candidate, one strategic avenue, lactate dehydrogenase release, imparting significant insights, amidst ongoing efforts, employed computational techniques, computational analyses suggest, molecular dynamics simulations, including molecular docking, 3 activity assays, hydroxyacetyl )- 4, 6s )- 4, promising anticancer candidates, via caspase 3, study &# 8217, knowledge holds potential, demonstrated marked efficacy
العلاقة: https://figshare.com/articles/figure/Intercalation_of_DNA_groove_by_compound_A02_/24890257Test
الإتاحة: https://doi.org/10.1371/journal.pone.0292455.g015Test
https://figshare.com/articles/figure/Intercalation_of_DNA_groove_by_compound_A02_/24890257Test -
17صورة
المؤلفون: Mubashir Aziz, Muhammad Sarfraz, Muhammad Khurrum Ibrahim, Syeda Abida Ejaz, Tasneem Zehra, Hanan A. Ogaly, Mosab Arafat, Fatimah A. M. Al-Zahrani, Chen Li
مصطلحات موضوعية: Biophysics, Biochemistry, Cell Biology, Genetics, Molecular Biology, Biotechnology, Cancer, Science Policy, Biological Sciences not elsewhere classified, Chemical Sciences not elsewhere classified, Information Systems not elsewhere classified, significant global cause, potent bioactive agents, particularly potent candidate, one strategic avenue, lactate dehydrogenase release, imparting significant insights, amidst ongoing efforts, employed computational techniques, computational analyses suggest, molecular dynamics simulations, including molecular docking, 3 activity assays, hydroxyacetyl )- 4, 6s )- 4, promising anticancer candidates, via caspase 3, study &# 8217, knowledge holds potential, demonstrated marked efficacy
الإتاحة: https://doi.org/10.1371/journal.pone.0292455.g017Test
https://figshare.com/articles/figure/The_amino_acid_residues_wise_fluctuation_RMSF_for_c_alpha_atoms_of_NF-_B_apo_protein_and_liganded_protein_NF-_B_-A01_complex_/24890263Test -
18صورة
المؤلفون: Mubashir Aziz, Muhammad Sarfraz, Muhammad Khurrum Ibrahim, Syeda Abida Ejaz, Tasneem Zehra, Hanan A. Ogaly, Mosab Arafat, Fatimah A. M. Al-Zahrani, Chen Li
مصطلحات موضوعية: Biophysics, Biochemistry, Cell Biology, Genetics, Molecular Biology, Biotechnology, Cancer, Science Policy, Biological Sciences not elsewhere classified, Chemical Sciences not elsewhere classified, Information Systems not elsewhere classified, significant global cause, potent bioactive agents, particularly potent candidate, one strategic avenue, lactate dehydrogenase release, imparting significant insights, amidst ongoing efforts, employed computational techniques, computational analyses suggest, molecular dynamics simulations, including molecular docking, 3 activity assays, hydroxyacetyl )- 4, 6s )- 4, promising anticancer candidates, via caspase 3, study &# 8217, knowledge holds potential, demonstrated marked efficacy
الإتاحة: https://doi.org/10.1371/journal.pone.0292455.g018Test
https://figshare.com/articles/figure/The_RMSD_pattern_for_the_apo_protein_P53_represented_by_the_blue_trajectory_and_the_liganded_protein_P53-A02_complex_represented_by_the_brown_trajectory_is_depicted_in_the_illustration_/24890266Test -
19صورة
المؤلفون: Mubashir Aziz, Muhammad Sarfraz, Muhammad Khurrum Ibrahim, Syeda Abida Ejaz, Tasneem Zehra, Hanan A. Ogaly, Mosab Arafat, Fatimah A. M. Al-Zahrani, Chen Li
مصطلحات موضوعية: Biophysics, Biochemistry, Cell Biology, Genetics, Molecular Biology, Biotechnology, Cancer, Science Policy, Biological Sciences not elsewhere classified, Chemical Sciences not elsewhere classified, Information Systems not elsewhere classified, significant global cause, potent bioactive agents, particularly potent candidate, one strategic avenue, lactate dehydrogenase release, imparting significant insights, amidst ongoing efforts, employed computational techniques, computational analyses suggest, molecular dynamics simulations, including molecular docking, 3 activity assays, hydroxyacetyl )- 4, 6s )- 4, promising anticancer candidates, via caspase 3, study &# 8217, knowledge holds potential, demonstrated marked efficacy
الإتاحة: https://doi.org/10.1371/journal.pone.0292455.g019Test
https://figshare.com/articles/figure/The_amino_acid_residues_wise_fluctuation_RMSF_of_Apo_protein_P53_and_liganded_protein_P53-A02_complex_/24890269Test -
20صورة
المؤلفون: Mubashir Aziz, Muhammad Sarfraz, Muhammad Khurrum Ibrahim, Syeda Abida Ejaz, Tasneem Zehra, Hanan A. Ogaly, Mosab Arafat, Fatimah A. M. Al-Zahrani, Chen Li
مصطلحات موضوعية: Biophysics, Biochemistry, Cell Biology, Genetics, Molecular Biology, Biotechnology, Cancer, Science Policy, Biological Sciences not elsewhere classified, Chemical Sciences not elsewhere classified, Information Systems not elsewhere classified, significant global cause, potent bioactive agents, particularly potent candidate, one strategic avenue, lactate dehydrogenase release, imparting significant insights, amidst ongoing efforts, employed computational techniques, computational analyses suggest, molecular dynamics simulations, including molecular docking, 3 activity assays, hydroxyacetyl )- 4, 6s )- 4, promising anticancer candidates, via caspase 3, study &# 8217, knowledge holds potential, demonstrated marked efficacy
الإتاحة: https://doi.org/10.1371/journal.pone.0292455.g021Test
https://figshare.com/articles/figure/Superimposed_structures_of_the_NF-_B-A01_complex_and_the_P53-A02_complex_were_observed_during_MD_simulation_/24890278Test
