المؤلفون: Sydney Stanley, Xin Wang, Qingyun Liu, Young Yon Kwon, Abigail M. Frey, Nathan D. Hicks, Andrew J. Vickers, Sheng Hui, Sarah M. Fortune

مصطلحات موضوعية: Biochemistry, Microbiology, Genetics, Molecular Biology, Evolutionary Biology, Ecology, Cancer, Infectious Diseases, Computational Biology, Environmental Sciences not elsewhere classified, providing experimental evidence, div >< p, central carbon metabolism, 1 virulence system, mycobacterium tuberculosis <, discernible growth defect, dependent antibiotic susceptibility, mutations functionally increase, human host environment, global clinical isolates, lactate dehydrogenase reveals, assessing mtb genes, 13 , clinical isolates, vivo <, mtb growth, lactate dehydrogenase, intracellular environment, host pressure, genes involved

العلاقة: https://figshare.com/articles/figure/Stepwise_evolution_of_LldD2_/25320174Test

الإتاحة: https://doi.org/10.1371/journal.ppat.1012050.g001Test
https://figshare.com/articles/figure/Stepwise_evolution_of_LldD2_/25320174Test

المؤلفون: Sydney Stanley, Xin Wang, Qingyun Liu, Young Yon Kwon, Abigail M. Frey, Nathan D. Hicks, Andrew J. Vickers, Sheng Hui, Sarah M. Fortune

مصطلحات موضوعية: Biochemistry, Microbiology, Genetics, Molecular Biology, Evolutionary Biology, Ecology, Cancer, Infectious Diseases, Computational Biology, Environmental Sciences not elsewhere classified, providing experimental evidence, div >< p, central carbon metabolism, 1 virulence system, mycobacterium tuberculosis <, discernible growth defect, dependent antibiotic susceptibility, mutations functionally increase, human host environment, global clinical isolates, lactate dehydrogenase reveals, assessing mtb genes, 13 , clinical isolates, vivo <, mtb growth, lactate dehydrogenase, intracellular environment, host pressure, genes involved

العلاقة: https://figshare.com/articles/figure/Lactate_and_i_lldD2_i_variants_remodel_the_Mtb_virulence_transcriptome_/25320186Test

الإتاحة: https://doi.org/10.1371/journal.ppat.1012050.g005Test
https://figshare.com/articles/figure/Lactate_and_i_lldD2_i_variants_remodel_the_Mtb_virulence_transcriptome_/25320186Test

المؤلفون: Sydney Stanley, Xin Wang, Qingyun Liu, Young Yon Kwon, Abigail M. Frey, Nathan D. Hicks, Andrew J. Vickers, Sheng Hui, Sarah M. Fortune

مصطلحات موضوعية: Biochemistry, Microbiology, Genetics, Molecular Biology, Evolutionary Biology, Ecology, Cancer, Infectious Diseases, Computational Biology, Environmental Sciences not elsewhere classified, providing experimental evidence, div >< p, central carbon metabolism, 1 virulence system, mycobacterium tuberculosis <, discernible growth defect, dependent antibiotic susceptibility, mutations functionally increase, human host environment, global clinical isolates, lactate dehydrogenase reveals, assessing mtb genes, 13 , clinical isolates, vivo <, mtb growth, lactate dehydrogenase, intracellular environment, host pressure, genes involved

العلاقة: https://figshare.com/articles/figure/_i_lldD2_i_homoplastic_mutations_modulate_gene_and_enzyme_activity_/25320183Test

الإتاحة: https://doi.org/10.1371/journal.ppat.1012050.g004Test
https://figshare.com/articles/figure/_i_lldD2_i_homoplastic_mutations_modulate_gene_and_enzyme_activity_/25320183Test

المؤلفون: Sydney Stanley, Xin Wang, Qingyun Liu, Young Yon Kwon, Abigail M. Frey, Nathan D. Hicks, Andrew J. Vickers, Sheng Hui, Sarah M. Fortune

مصطلحات موضوعية: Biochemistry, Microbiology, Genetics, Molecular Biology, Evolutionary Biology, Ecology, Cancer, Infectious Diseases, Computational Biology, Environmental Sciences not elsewhere classified, providing experimental evidence, div >< p, central carbon metabolism, 1 virulence system, mycobacterium tuberculosis <, discernible growth defect, dependent antibiotic susceptibility, mutations functionally increase, human host environment, global clinical isolates, lactate dehydrogenase reveals, assessing mtb genes, 13 , clinical isolates, vivo <, mtb growth, lactate dehydrogenase, intracellular environment, host pressure, genes involved

العلاقة: https://figshare.com/articles/figure/Ancestral_and_homoplastic_mutations_in_i_lldD2_i_augment_Mtb_fitness_in_lactate_/25320180Test

الإتاحة: https://doi.org/10.1371/journal.ppat.1012050.g003Test
https://figshare.com/articles/figure/Ancestral_and_homoplastic_mutations_in_i_lldD2_i_augment_Mtb_fitness_in_lactate_/25320180Test

المؤلفون: Sydney Stanley, Xin Wang, Qingyun Liu, Young Yon Kwon, Abigail M. Frey, Nathan D. Hicks, Andrew J. Vickers, Sheng Hui, Sarah M. Fortune

مصطلحات موضوعية: Biochemistry, Microbiology, Genetics, Molecular Biology, Evolutionary Biology, Ecology, Cancer, Infectious Diseases, Computational Biology, Environmental Sciences not elsewhere classified, providing experimental evidence, div >< p, central carbon metabolism, 1 virulence system, mycobacterium tuberculosis <, discernible growth defect, dependent antibiotic susceptibility, mutations functionally increase, human host environment, global clinical isolates, lactate dehydrogenase reveals, assessing mtb genes, 13 , clinical isolates, vivo <, mtb growth, lactate dehydrogenase, intracellular environment, host pressure, genes involved

العلاقة: https://figshare.com/articles/figure/Prevalence_of_various_LldD2_mutations_/25320177Test

الإتاحة: https://doi.org/10.1371/journal.ppat.1012050.g002Test
https://figshare.com/articles/figure/Prevalence_of_various_LldD2_mutations_/25320177Test

المؤلفون: Sydney Stanley, Xin Wang, Qingyun Liu, Young Yon Kwon, Abigail M. Frey, Nathan D. Hicks, Andrew J. Vickers, Sheng Hui, Sarah M. Fortune

مصطلحات موضوعية: Biochemistry, Microbiology, Genetics, Molecular Biology, Evolutionary Biology, Ecology, Cancer, Infectious Diseases, Computational Biology, Environmental Sciences not elsewhere classified, providing experimental evidence, div >< p, central carbon metabolism, 1 virulence system, mycobacterium tuberculosis <, discernible growth defect, dependent antibiotic susceptibility, mutations functionally increase, human host environment, global clinical isolates, lactate dehydrogenase reveals, assessing mtb genes, 13 , clinical isolates, vivo <, mtb growth, lactate dehydrogenase, intracellular environment, host pressure, genes involved

العلاقة: https://figshare.com/articles/figure/Ancestral_and_homoplastic_mutations_in_i_lldD2_i_augment_Mtb_fitness_in_lactate_/25320180Test

الإتاحة: https://doi.org/10.1371/journal.ppat.1012050.g003Test

المؤلفون: Sydney Stanley, Xin Wang, Qingyun Liu, Young Yon Kwon, Abigail M. Frey, Nathan D. Hicks, Andrew J. Vickers, Sheng Hui, Sarah M. Fortune

مصطلحات موضوعية: Biochemistry, Microbiology, Genetics, Molecular Biology, Evolutionary Biology, Ecology, Cancer, Infectious Diseases, Computational Biology, Environmental Sciences not elsewhere classified, providing experimental evidence, div >< p, central carbon metabolism, 1 virulence system, mycobacterium tuberculosis <, discernible growth defect, dependent antibiotic susceptibility, mutations functionally increase, human host environment, global clinical isolates, lactate dehydrogenase reveals, assessing mtb genes, 13 , clinical isolates, vivo <, mtb growth, lactate dehydrogenase, intracellular environment, host pressure, genes involved

العلاقة: https://figshare.com/articles/figure/Stepwise_evolution_of_LldD2_/25320174Test

الإتاحة: https://doi.org/10.1371/journal.ppat.1012050.g001Test

المؤلفون: Sydney Stanley, Xin Wang, Qingyun Liu, Young Yon Kwon, Abigail M. Frey, Nathan D. Hicks, Andrew J. Vickers, Sheng Hui, Sarah M. Fortune

مصطلحات موضوعية: Biochemistry, Microbiology, Genetics, Molecular Biology, Evolutionary Biology, Ecology, Cancer, Infectious Diseases, Computational Biology, Environmental Sciences not elsewhere classified, providing experimental evidence, div >< p, central carbon metabolism, 1 virulence system, mycobacterium tuberculosis <, discernible growth defect, dependent antibiotic susceptibility, mutations functionally increase, human host environment, global clinical isolates, lactate dehydrogenase reveals, assessing mtb genes, 13 , clinical isolates, vivo <, mtb growth, lactate dehydrogenase, intracellular environment, host pressure, genes involved

العلاقة: https://figshare.com/articles/figure/Prevalence_of_various_LldD2_mutations_/25320177Test

الإتاحة: https://doi.org/10.1371/journal.ppat.1012050.g002Test

المؤلفون: Sydney Stanley, Xin Wang, Qingyun Liu, Young Yon Kwon, Abigail M. Frey, Nathan D. Hicks, Andrew J. Vickers, Sheng Hui, Sarah M. Fortune

مصطلحات موضوعية: Biochemistry, Microbiology, Genetics, Molecular Biology, Evolutionary Biology, Ecology, Cancer, Infectious Diseases, Computational Biology, Environmental Sciences not elsewhere classified, providing experimental evidence, div >< p, central carbon metabolism, 1 virulence system, mycobacterium tuberculosis <, discernible growth defect, dependent antibiotic susceptibility, mutations functionally increase, human host environment, global clinical isolates, lactate dehydrogenase reveals, assessing mtb genes, 13 , clinical isolates, vivo <, mtb growth, lactate dehydrogenase, intracellular environment, host pressure, genes involved

العلاقة: https://figshare.com/articles/figure/Lactate_and_i_lldD2_i_variants_remodel_the_Mtb_virulence_transcriptome_/25320186Test

الإتاحة: https://doi.org/10.1371/journal.ppat.1012050.g005Test

المؤلفون: Sydney Stanley, Xin Wang, Qingyun Liu, Young Yon Kwon, Abigail M. Frey, Nathan D. Hicks, Andrew J. Vickers, Sheng Hui, Sarah M. Fortune

مصطلحات موضوعية: Biochemistry, Microbiology, Genetics, Molecular Biology, Evolutionary Biology, Ecology, Cancer, Infectious Diseases, Computational Biology, Environmental Sciences not elsewhere classified, providing experimental evidence, div >< p, central carbon metabolism, 1 virulence system, mycobacterium tuberculosis <, discernible growth defect, dependent antibiotic susceptibility, mutations functionally increase, human host environment, global clinical isolates, lactate dehydrogenase reveals, assessing mtb genes, 13 , clinical isolates, vivo <, mtb growth, lactate dehydrogenase, intracellular environment, host pressure, genes involved

العلاقة: https://figshare.com/articles/figure/_i_lldD2_i_homoplastic_mutations_modulate_gene_and_enzyme_activity_/25320183Test

الإتاحة: https://doi.org/10.1371/journal.ppat.1012050.g004Test