أخبار
Global cellular regulation including cardiac function by post-translational protein arginylation.
| العنوان: | Global cellular regulation including cardiac function by post-translational protein arginylation. |
|---|---|
| المؤلفون: | Kaji, Hideko, Kaji, Akira |
| المصدر: | Department of Biochemistry and Molecular Biology Faculty Papers |
| بيانات النشر: | Jefferson Digital Commons |
| سنة النشر: | 2012 |
| المجموعة: | Jefferson Digital Commons (Thomas Jefferson University, Philadelphia) |
| مصطلحات موضوعية: | Thomas Jefferson University, Department of Biochemistry and Molecular Biology, Amino Acid Sequence, Aminoacyltransferases/deficiency, Aminoacyltransferases/genetics, Aminoacyltransferases/metabolism, Animals, Arginine/chemistry, Arginine/metabolism, Cytoskeletal Proteins/metabolism, Gene Expression Regulation, Developmental, Gene Silencing, Mice, Knockout, Molecular Sequence Data, Proteasome Endopeptidase Complex/antagonists & inhibitors, Proteasome Endopeptidase, Complex/metabolism, Protein Processing, Post-Translational, Proteins/metabolism, Sequence Analysis, Protein, Medical Biochemistry |
| الوصف: | In this issue a very significant contribution to cardiology describing critical roles of ATE1 appears by Kurosaka et al. [1]. In view of this paper, as the discoverers of ATE1, we have been asked to contribute an article (editorial) regarding ATE1 (enzyme which transfers arginine from arginyl tRNA to protein acceptors). This short article consists of three sections: 1) a historical anecdote describing how ATE1 was discovered; 2) its possible role in aging and cellular transformation, and most importantly; 3) its role in the development and maintenance of cardiac activity. The last section has direct bearing to the Kurosaka et al. paper. © Elsevier B.V. |
| نوع الوثيقة: | other non-article part of journal/newspaper |
| وصف الملف: | application/pdf |
| اللغة: | unknown |
| العلاقة: | https://jdc.jefferson.edu/bmpfp/41Test; https://jdc.jefferson.edu/context/bmpfp/article/1040/viewcontent/YJMCC_2012.pdfTest |
| الإتاحة: | https://jdc.jefferson.edu/bmpfp/41Test https://jdc.jefferson.edu/context/bmpfp/article/1040/viewcontent/YJMCC_2012.pdfTest |
| رقم الانضمام: | edsbas.182538F5 |
| قاعدة البيانات: | BASE |
| الوصف غير متاح. |