دورية
Changes in gene expression following trauma are related to the age of transfused packed red blood cells
العنوان: | Changes in gene expression following trauma are related to the age of transfused packed red blood cells |
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المؤلفون: | Torrance, Hew D.T., Vivian, Mark E., Brohi, Karim, Prowle, John R., Pearse, Rupert M., Owen, Helen C., Hinds, Charles J., O’Dwyer, Michael J. |
المصدر: | Journal of Trauma and Acute Care Surgery; March 2015, Vol. 78 Issue: 3 p535-542, 8p |
مستخلص: | Transfusion of packed red blood cells (PRBCs) is associated with an increased incidence of nosocomial infections and an increased risk of death. The duration of storage before transfusion may influence these outcomes. Here, we explore the association between the age of transfused PRBCs and specific patterns of inflammatory gene expression in severely injured trauma patients. |
قاعدة البيانات: | Supplemental Index |
تدمد: | 21630755 21630763 |
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DOI: | 10.1097/TA.0000000000000534 |