دورية أكاديمية
Chemiluminescence of bovine polymorphonuclear leucocytes during the periparturient period and relation with metabolic markers and bovine pregnancy-associated glycoprotein.
| العنوان: | Chemiluminescence of bovine polymorphonuclear leucocytes during the periparturient period and relation with metabolic markers and bovine pregnancy-associated glycoprotein. |
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| المؤلفون: | Hoeben, Dagmar, Monfardini, Erica, Opsomer, Geert, Burvenich, Christian, Dosogne, Hilde, De Kruif, Aart, Beckers, Jean-François |
| المصدر: | Journal of Dairy Research, 67 (2), 249 - 259 (2000-05) |
| بيانات النشر: | Cambridge University Press (CUP), 2000. |
| سنة النشر: | 2000 |
| مصطلحات موضوعية: | Biomarkers, Blood Glucose, Fatty Acids, Nonesterified, Pregnancy Proteins, Cholesterol, L-Lactate Dehydrogenase, Aspartate Aminotransferases, Aspartic Acid Endopeptidases, pregnancy-associated glycoprotein 1, Bilirubin, 3-Hydroxybutyric Acid, 3-Hydroxybutyric Acid/blood, Animals, Aspartate Aminotransferases/blood, Aspartic Acid Endopeptidases/blood, Bilirubin/blood, Biomarkers/blood, Blood Glucose/analysis, Cholesterol/blood, Fatty Acids, Nonesterified/blood, Female, Gestational Age, L-Lactate Dehydrogenase/blood, Labor, Obstetric, Leukocyte Count, Neutrophils/physiology, Postpartum Period, Pregnancy, Pregnancy Proteins/blood, Respiratory Burst, Cattle, Luminescent Measurements, Food Science, Animal Science and Zoology, General Medicine, Life sciences, Veterinary medicine & animal health, Sciences du vivant, Médecine vétérinaire & santé animale |
| الوصف: | The respiratory burst activity of polymorphonuclear leucocytes (PMN) was evaluated in eight Holstein cows from 8 weeks before until 6 weeks after calving by chemiluminescence (CL). The CL response started to decrease 1 week before parturition, reaching a minimum during the first 2 weeks after calving. From week 3 of lactation, CL increased again and returned to original levels by week 6 of lactation. Plasma concentrations of 3-hydroxybutyric acid, total bilirubin and bovine pregnancy-associated glycoprotein started to increase before parturition to reach a maximum during the first or second week of lactation. The concentrations of glutamic-oxaloacetic transaminase, lactate dehydrogenase, non-esterified fatty acids and bilirubin increased after calving, reaching a maximum during the second week. A small decrease in plasma cholesterol during the week before and after calving was followed by an increase. The CL response of the PMN showed significant temporal relationships with the plasma concentrations of 3-hydroxybutyric acid, bovine pregnancy-associated glycoprotein, bilirubin, glutamic-oxaloacetic transaminase, non-esterified fatty acids; that with cholesterol was nearly significant. This means that the change in the CL response with time coincided with the changes in plasma concentrations of these substances with time and that these changes were significantly related with each other. The results of this study show that the decreased respiratory burst activity of bovine PMN around parturition may be related to the extent of the metabolic and hormonal changes. Although the causative relationships are not proven, these results support earlier results suggesting that 3-hydroxybutyric acid and bovine pregnancy-associated glycoprotein may directly affect neutrophil function, whereas non-esterified fatty acids, cholesterol, bilirubin, and liver enzymes may have potential as diagnostic markers of impaired neutrophil function and consequently increased disease risk around parturition. |
| نوع الوثيقة: | journal article http://purl.org/coar/resource_type/c_6501Test article peer reviewed |
| اللغة: | English |
| العلاقة: | https://www.cambridge.org/core/services/aop-cambridge-core/content/view/S0022029900004052Test; urn:issn:0022-0299; urn:issn:1469-7629 |
| DOI: | 10.1017/s0022029900004052 |
| الوصول الحر: | https://orbi.uliege.be/handle/2268/298357Test |
| حقوق: | restricted access http://purl.org/coar/access_right/c_16ecTest info:eu-repo/semantics/restrictedAccess |
| رقم الانضمام: | edsorb.298357 |
| قاعدة البيانات: | ORBi |
| DOI: | 10.1017/s0022029900004052 |
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