مورد إلكتروني

Microbial characteristics in homes of asthmatic and non-asthmatic adults in the ECRHS cohort

التفاصيل البيبلوغرافية
العنوان: Microbial characteristics in homes of asthmatic and non-asthmatic adults in the ECRHS cohort
بيانات النشر: Wiley
تفاصيل مُضافة: 1 ] Natl Inst Hlth & Welf, Living Environm & Hlth Unit, Kuopio, Finland Show more [ 2 ] Univ Eastern Finland, Dept Environm & Biol Sci, Kuopio, Finland Show more [ 3 ] Univ Helsinki, Dept Publ Hlth, Helsinki, Finland Show more [ 4 ] Ctr Res Environm Epidemiol CREAL, ISGlobal, Barcelona, Spain Show more [ 5 ] UPF, Barcelona, Spain Show more [ 6 ] CIBERESP, Barcelona, Spain Show more [ 7 ] Katholieke Univ Leuven, Dept Publ Hlth & Primary Care, Ctr Environm & Hlth, Leuven, Belgium [ 8 ] Res Fdn Flanders FWO, Brussels, Belgium Show more [ 9 ] Swiss Trop & Publ Hlth Inst, Head Dept Epidemiol & Publ Hlth, Basel, Switzerland Show more [ 10 ] Univ Basel, Dept Publ Hlth, Basel, Switzerland Show more [ 11 ] Umea Univ, Dept Publ Hlth & Clin Med, Occupat & Environm Med, Umea, Sweden Show more [ 12 ] Sahlgrens Univ Hosp, Dept Occupat & Environm Med, Gothenburg, Sweden Show more [ 13 ] Uppsala Univ, Dept Med Sci, Uppsala, Sweden Show more [ 14 ] Univ Grenoble Alpes, INSERM, CHU Grenoble Alpes, U 1209, Grenoble, France [ 15 ] Landspitali Univ Hosp E7, Dept Resp Med & Sleep, Reykjavik, Iceland Show more [ 16 ] Univ Iceland, Fac Med, Reykjavik, Iceland Show more [ 17 ] Imperial Coll, Natl Heart & Lung Inst, Populat Hlth & Occupat Dis, London, England Show more [ 18 ] Imperial Coll, MRC PHE Ctr Environm & Hlth, London, England Show more [ 19 ] Ludwig Maximillians Univ Munich, Univ Hosp Munich, Inst & Outpatient Clin Occupat Social & Environm, German Ctr Lung Res DZL, Munich, Germany Show more [ 20 ] German Res Ctr Environm Hlth, Inst Epidemiol 1, Helmholtz Zentrum Munchen, Neuherberg, German
Living Environment and Health Unit; National Institute for Health and Welfare; Kuopio Finland
ISGlobal; Centre for Research in Environmental Epidemiology (CREAL); Barcelona Spain
Centre for Environment and Health - Department of Public Health and Primary Care; KU Leuven; Leuven Belgium
Head Department Epidemiology and Public Health; Swiss Tropical and Public Health Institute; Basel Switzerland
Department of Public Health and Clinical Medicine, Occupational and Environmental Medicine; Umeå University; Umeå Sweden
Department of Occupational and Environmental Medicine; Sahlgrenska University Hospital; Gothenburg Sweden
Department of Medical Sciences; Uppsala University; Uppsala Sweden
CHU de Grenoble Alpes; INSERM U 1209; Université Grenoble Alpes; Grenoble France
Department of Respiratory Medicine and Sleep; Landspitali University Hospital (E7); Reykjavik Iceland
Population Health and Occupational Disease; Imperial College; National Heart and Lung Institute; London UK
Institute and Outpatient Clinic for Occupational, Social and Environmental Medicine; University Hospital Munich; Ludwig Maximillians University Munich; Member of German Center for Lung Research (DZL); Munich Germany
Valkonen, M.
Täubel, M.
Pekkanen, J.
Tischer, C.
Rintala, H.
Zock, J.-P.
Casas, L.
Probst-Hensch, N.
Forsberg, B.
Holm, M.
Janson, C.
Pin, I.
Gislason, T.
Jarvis, D.
Heinrich, J.
Hyvärinen, A.
نوع الوثيقة: Electronic Resource
مستخلص: To access publisher's full text version of this article click on the hyperlink below
Microbial exposures in homes of asthmatic adults have been rarely investigated; specificities and implications for respiratory health are not well understood. The objectives of this study were to investigate associations of microbial levels with asthma status, asthma symptoms, bronchial hyperresponsiveness (BHR), and atopy. Mattress dust samples of 199 asthmatics and 198 control subjects from 7 European countries participating in the European Community Respiratory Health Survey II study were analyzed for fungal and bacterial cell wall components and individual taxa. We observed trends for protective associations of higher levels of mostly bacterial markers. Increased levels of muramic acid, a cell wall component predominant in Gram-positive bacteria, tended to be inversely associated with asthma (OR's for different quartiles: II 0.71 [0.39-1.30], III 0.44 [0.23-0.82], and IV 0.60 [0.31-1.18] P for trend .07) and with asthma score (P for trend .06) and with atopy (P for trend .02). These associations were more pronounced in northern Europe. This study among adults across Europe supports a potential protective effect of Gram-positive bacteria in mattress dust and points out that this may be more pronounced in areas where microbial exposure levels are generally lower.
مصطلحات الفهرس: Asma, Innahússveppir, Rykmaurar, PAD12, Article
URL: http://hdl.handle.net/2336/620441Test
http://www.hirsla.lsh.is/lsh/handle/2336/620441Test
http://doi.wiley.com/10.1111/ina.12427Test
http://doi.wiley.com/10.1111/ina.12427Test
الإتاحة: Open access content. Open access content
National Consortium - Landsaðgangur
Archived with thanks to Indoor Air
ملاحظة: Microbial characteristics in homes of asthmatic and non-asthmatic adults in the ECRHS cohort 2018, 28 (1):16 Indoor Air
English
أرقام أخرى: LM$ oai:www.hirsla.lsh.is:2336/620441
Microbial characteristics in homes of asthmatic and non-asthmatic adults in the ECRHS cohort 2018, 28 (1):16 Indoor Air
09056947
10.1111/ina.12427
Indoor Air
1021212381
المصدر المساهم: LANDSPITALINN MED LIBR
From OAIster®, provided by the OCLC Cooperative.
رقم الانضمام: edsoai.on1021212381
قاعدة البيانات: OAIster