مورد إلكتروني
Dyslipidemia Treatment and Lipid Control in US Adults with Diabetes by Sociodemographic and Cardiovascular Risk Groups in the NIH Precision Medicine Initiative All of Us Research Program.
| العنوان: | Dyslipidemia Treatment and Lipid Control in US Adults with Diabetes by Sociodemographic and Cardiovascular Risk Groups in the NIH Precision Medicine Initiative All of Us Research Program. |
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| المؤلفون: | Akbarpour, Meleeka |
| المصدر: | Journal of clinical medicine; vol 12, iss 4, 1668; 2077-0383 |
| بيانات النشر: | eScholarship, University of California 2023-02-01 |
| تفاصيل مُضافة: | Akbarpour, Meleeka Devineni, Divya Gong, Yufan Wong, Nathan D |
| نوع الوثيقة: | Electronic Resource |
| مستخلص: | Real-world data on lipid levels and treatment among adults with diabetes mellitus (DM) are relatively limited. We studied lipid levels and treatment status in patients with DM across cardiovascular disease (CVD) risk groups and sociodemographic factors. In the All of Us Research Program, we categorized DM as (1) moderate risk (≤1 CVD risk factor), (2) high risk (≥2 CVD risk factors), and (3) DM with atherosclerotic CVD (ASCVD). We examined the use of statin and non-statin therapy as well as LDL-C and triglyceride levels. We studied 81,332 participants with DM, which included 22.3% non-Hispanic Black and 17.2% Hispanic. A total of 31.1% had ≤1 DM risk factor, 30.3% had ≥2 DM risk factors, and 38.6% of participants had DM with ASCVD. Only 18.2% of those with DM and ASCVD were on high-intensity statins. Overall, 5.1% were using ezetimibe and 0.6% PCSK9 inhibitors. Among those with DM and ASCVD, only 21.1% had LDL-C < 70 mg/dL. Overall, 1.9% of participants with triglycerides ≥ 150 mg/dL were on icosapent ethyl. Those with DM and ASCVD were more likely to be on high-intensity statins, ezetimibe, and icosapent ethyl. Guideline-recommended use of high-intensity statins and non-statin therapy among our higher risk DM patients is lacking, with LDL-C inadequately controlled. |
| مصطلحات الفهرس: | LDL-cholesterol, diabetes mellitus, dyslipidemia, statins, treatment, triglycerides, Prevention, Diabetes, Atherosclerosis, Cardiovascular, Heart Disease, Patient Safety, Clinical Research, Good Health and Well Being, Clinical Sciences, article |
| URL: | |
| الإتاحة: | Open access content. Open access content public |
| ملاحظة: | application/pdf Journal of clinical medicine vol 12, iss 4, 1668 2077-0383 |
| أرقام أخرى: | CDLER oai:escholarship.org:ark:/13030/qt8j58f2k3 qt8j58f2k3 https://escholarship.org/uc/item/8j58f2k3Test https://escholarship.orgTest/ 1391581700 |
| المصدر المساهم: | UC MASS DIGITIZATION From OAIster®, provided by the OCLC Cooperative. |
| رقم الانضمام: | edsoai.on1391581700 |
| قاعدة البيانات: | OAIster |
| الوصف غير متاح. |