رسالة جامعية
Reproduction, Hysterectomy and Risk of Cardiovascular Disease
| العنوان: | Reproduction, Hysterectomy and Risk of Cardiovascular Disease |
|---|---|
| المؤلفون: | Kharazmi, Elham |
| المساهمون: | Terveystieteen laitos - Tampere School of Public Health, Lääketieteellinen tiedekunta - Faculty of Medicine, University of Tampere |
| بيانات النشر: | Tampere University Press |
| سنة النشر: | 2008 |
| مصطلحات موضوعية: | Cardiovascular diseases, pregnancy, hysterectomy, reproductive history, Epidemiologia - Epidemiology |
| الوصف: | Background: Cardiovascular disease (CVD), the most common cause of death in most developed countries, have gender-specific characteristics. Protective effect of endogenous estrogen for CVD is established. In older ages, women have similar rates of CVD, and even a higher prevalence of hypertension than that of men. Although CVD is considered as a man s disease , CVD kills more women. Most of our knowledge about management guidelines for CVD in women arise from studies conducted mostly in men. The increasing number of women with CVD shows the substantial need for identification of those specific variables relevant to cardiovascular health in women. Whether pregnancy-related factors and hysterectomy would reveal some of these variables and risk for CVD, is still uncertain. Objective: To further elucidate the associations between reproduction, hysterectomy, and risk of CVD in women. Materials and methods: Data were obtained from Health 2000 study, a cross-sectional comprehensive survey carried out in 2000-1 in Finland, except for Study II. Study I comprised 746 Finnish women aged 45-74, in which associations of reproductive history (assessed by questionnaire) and measures of subclinical atherosclerosis (by ultrasonographic detection) were studied. In Study III, associations between pregnancy-related factors and isolated systolic hypertension (ISH) were assessed in 3,937 Finnish women aged 30-99. In Study IV, data of 2,514 Finnish women aged 30-99 were used to investigate associations between hysterectomy and CVD. A total of 4,090 Finnish women who delivered in the period 1954-1963 were followed up for an average of 44 years in Study II. Mortality data were obtained from the Finnish cause-of-death registry. Logistic, linear regression and Cox-proportional hazard models were used for analysis. Results: Women with a history of stillbirth tended to have higher IMT than other women. A history of stillbirth was associated with an increased age-adjusted risk of plaque [Odd ratio (OR): 3.43, 95% CI: 1.07-11.05] but in the ... |
| نوع الوثيقة: | doctoral or postdoctoral thesis |
| وصف الملف: | fulltext |
| اللغة: | English |
| ردمك: | 978-951-44-7331-9 951-44-7331-0 |
| تدمد: | 1456-954X |
| العلاقة: | Acta Electronica Universitatis Tamperensis; 729; https://trepo.tuni.fi/handle/10024/67856Test; urn:isbn:978-951-44-7331-9 |
| الإتاحة: | https://trepo.tuni.fi/handle/10024/67856Test |
| حقوق: | This publication is copyrighted. You may download, display and print it for Your own personal use. Commercial use is prohibited. ; openAccess |
| رقم الانضمام: | edsbas.A78C6FCB |
| قاعدة البيانات: | BASE |
| ردمك: | 9789514473319 9514473310 |
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| تدمد: | 1456954X |