التفاصيل البيبلوغرافية
العنوان: |
Inflammatory Type 2 cDCs Acquire Features of cDC1s and Macrophages to Orchestrate Immunity to Respiratory Virus Infection |
المؤلفون: |
Bosteels, Cedric, Neyt, Katrijn, Vanheerswynghels, Manon, van Helden, Mary J., Sichien, Dorine, Debeuf, Nincy, De Prijck, Sofie, Bosteels, Victor, Vandamme, Niels, Martens, Liesbet, Saeys, Yvan, Louagie, Els, Lesage, Manon, Williams, David L., Tang, Shiau Choot, Mayer, Johannes U., Ronchese, Franca, Scott, Charlotte L., Hammad, Hamida, Guilliams, Martin, Lambrecht, Bart N. |
المصدر: |
ETSU Faculty Works. |
بيانات النشر: |
Digital Commons @ East Tennessee State University. |
المجموعة: |
East Tennessee State University |
مصطلحات موضوعية: |
CD64, convalescent serum, dendritic cell, Fc receptor, inf-cDC2, inflammation, IRF8, monocyte, transcription factor, type 1 interferon, virus, Surgery |
الوصف: |
The dichotomy between type 1 and 2 conventional DCs under steady-state conditions is well defined. Bosteels et al. demonstrate that, upon inflammation, cDC2s acquire a hybrid inf-cDC2 phenotype, sharing phenotype, gene expression, and function with cDC1s and monocyte-derived cells, to optimally boost CD4 and CD8 immunity via Fc receptors. |
Original Identifier: |
oai:dc.etsu.edu:etsu-works-10418 |
نوع الوثيقة: |
text |
DOI: |
10.1016/j.immuni.2020.04.005 |
الإتاحة: |
https://dc.etsu.edu/etsu-works/9152Test |
رقم الانضمام: |
edsndl.ETSU.oai.dc.etsu.edu.etsu.works.10418 |
قاعدة البيانات: |
Networked Digital Library of Theses & Dissertations |