المؤلفون: Hjorth, Kansadarat, Carbin Menyes, Erika

مصطلحات موضوعية: Type 1 diabetes mellitus, transfers, adolescence, adult, experiences, Typ 1 diabetes mellitus, övergÃ¥ng, barn, vuxen, erfarenheter, Nursing, OmvÃ¥rdnad

الوصف: Bakgrund: Incidensen för typ 1-diabetes ökar under barndomen vilket betyder att allt flera ungdomar kommer att genomgaÌŠ överföringen fraÌŠn barndiabetesmottagningen till vuxendiabetesmottagning. Syfte: Syftet med uppsatsen var att belysa upplevelsen av överföringen fraÌŠn barndiabetesmottagning till vuxendiabetesmottagning ur olika perspektiv. Metod: En kvalitativ metasyntes. Sökningar gjordes paÌŠ databaserna CINAHL och PubMed. Nio artiklar som svarar paÌŠ författarnas syfte hittades, aÌŠtta kvalitativa och en mixed-method. Resultat: Fyra huvudteman identifierades: utmaningar att navigera, stödets funktion, inför överföringen till VDM och förväntningar. Vidare identifierades undertema för tre av huvudteman. Underteman till utmaningar att navigera var: ungdomarnas maÌŠnga utmaningar att navigera livet med T1D och vaÌŠrdnadshavarnas utmaningar att navigera en ny roll. Underteman till inför överföringen var: tidigare förbereda överföringen och utbildning och upprepning av grunderna. Underteman till förväntningar var: innan överföringen och efter överföringen. Slutsats: Ungdomar genomgaÌŠr en stor förändring i livet och den sena tonaÌŠrstiden är präglad med stora förändringar och beslut. Överföringen fraÌŠn barndiabetesmottagning till vuxendiabetesmottagning utgör en extra saÌŠrbar tid för ungdomarna. Resultatet visar paÌŠ att baÌŠde ungdomarna och vaÌŠrdnadshavarna uttrycker stor oro och aÌŠngest inför överföringen. Det är viktigt att diabetessjuksköterskan tidigt börjar förbereda ungdomarna och vaÌŠrdnadshavarna inför överföringen för bästa möjliga resultat för alla inblandade. Ungdomarna uttrycker stor önskan om att faÌŠ repetition och utbildning i grunderna inom diabetes. ; Background: The incidence of type 1 diabetes increases during childhood, which means that more and more adolescence will undergo the transfer from the pediatric diabetes clinic to the adult diabetes clinic. Aim: The purpose was to ...

وصف الملف: application/pdf

العلاقة: http://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-530763Test

الإتاحة: http://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-530763Test

المؤلفون: Alyassin, Issam, Wahlström, Viktor

مصطلحات موضوعية: Adult, diabetes type 1, experience, patients, self-care, Egenvård, diabetes typ 1, patient, upplevelse, vuxen, Nursing, Omvårdnad

الوصف: Bakgrund: Diabetes typ 1 är en kronisk sjukdom som drabbar många människor i världen. Sjukdomen kan leda till många olika komplikationer om egenvård inte främjas. För att förebygga diabeteskomplikationer krävs det livsstilsförändring i form av hälsosam kost och fysiska aktiviteter. För att patienten ska vara delaktig i sin egenvård krävs det att sjuksköterskan framhäver patientens styrkor och motiverar dem till delaktighet i egenvård. Syfte: Att beskriva patienters upplevelser av egenvård vid diabetes typ 1. Metod: Metoden som användes i studien var en litteraturstudie baserad på kvalitativ forskning. 13 kvalitativa vetenskapliga artiklar med kvalitativ ansats granskades och analyserades genom Fribergs fem steg för en integrerande sammanfattning. Resultat: Patienter upplever att kunskap, stabila blodsockervärden, stöd från sjukvården, omgivningen och hjälpmedel ger känslan av trygghet. För att uppnå detta och kunna ta det egna ansvaret krävs att patienterna accepterar sin sjukdom och situationen som de befinner sig i. Rädsla och stress är ständigt närvarande hos patienterna och något som de behöver handskas med dagligen. Konklusion: Faktorer som påverkar blodsockernivåerna är något som ständigt är närvarande hos patienter med diabetes typ 1. Sjuksköterskans ansvarsområde är att utbilda patienterna utifrån deras individuella behov med syfte att öka kunskap, vilket bidrar till bättre egenvård och ökad trygghet i vardagen.
Background: Diabetes type 1 is a chronic disease that affects many people in the world. If there is no suitable self-care, this disease can lead to many different complications. To prevent diabetes complications, lifestyle changes in the form of a healthy diet and physical activities are required. For the patient to be involved in their care, the nurse must highlight the patient's strengths and motivate them to participate in self-care. Aim: To describe patients' experiences of self-care in diabetes type 1. Method: The method used in the study was a literature study based on qualitative research. 13 qualitative scientific articles with a qualitative approach were reviewed and analyzed through Friberg’s five steps for an integrative summary. Findings: Patients feel that knowledge, stable blood sugar values, support from the healthcare system, the environment and utils provide a sense of security. To achieve this and be able to take their own responsibility, patients must accept their illness and the situation they are in. Fear and stress are constantly present and something these patients need to deal with on a daily basis. Conclusion: Factors that affect blood sugar levels are constantly present in patients with type 1 diabetes. The nurse's area of responsibility is to educate patients based on their individual needs with the aim of increasing knowledge, which contributes to better self-care and increased security in everyday life.

وصف الملف: application/pdf

الإتاحة: http://urn.kb.se/resolve?urn=urn:nbn:se:his:diva-23434Test

المؤلفون: Alyassin, Issam, Wahlström, Viktor

مصطلحات موضوعية: Adult, diabetes type 1, experience, patients, self-care, Egenvård, diabetes typ 1, patient, upplevelse, vuxen, Nursing, Omvårdnad

الوصف: Bakgrund: Diabetes typ 1 är en kronisk sjukdom som drabbar många människor i världen. Sjukdomen kan leda till många olika komplikationer om egenvård inte främjas. För att förebygga diabeteskomplikationer krävs det livsstilsförändring i form av hälsosam kost och fysiska aktiviteter. För att patienten ska vara delaktig i sin egenvård krävs det att sjuksköterskan framhäver patientens styrkor och motiverar dem till delaktighet i egenvård. Syfte: Att beskriva patienters upplevelser av egenvård vid diabetes typ 1. Metod: Metoden som användes i studien var en litteraturstudie baserad på kvalitativ forskning. 13 kvalitativa vetenskapliga artiklar med kvalitativ ansats granskades och analyserades genom Fribergs fem steg för en integrerande sammanfattning. Resultat: Patienter upplever att kunskap, stabila blodsockervärden, stöd från sjukvården, omgivningen och hjälpmedel ger känslan av trygghet. För att uppnå detta och kunna ta det egna ansvaret krävs att patienterna accepterar sin sjukdom och situationen som de befinner sig i. Rädsla och stress är ständigt närvarande hos patienterna och något som de behöver handskas med dagligen. Konklusion: Faktorer som påverkar blodsockernivåerna är något som ständigt är närvarande hos patienter med diabetes typ 1. Sjuksköterskans ansvarsområde är att utbilda patienterna utifrån deras individuella behov med syfte att öka kunskap, vilket bidrar till bättre egenvård och ökad trygghet i vardagen. ; Background: Diabetes type 1 is a chronic disease that affects many people in the world. If there is no suitable self-care, this disease can lead to many different complications. To prevent diabetes complications, lifestyle changes in the form of a healthy diet and physical activities are required. For the patient to be involved in their care, the nurse must highlight the patient's strengths and motivate them to participate in self-care. Aim: To describe patients' experiences of self-care in diabetes type 1. Method: The method used in the study was a literature study based on qualitative ...

وصف الملف: application/pdf

العلاقة: http://urn.kb.se/resolve?urn=urn:nbn:se:his:diva-23434Test

الإتاحة: http://urn.kb.se/resolve?urn=urn:nbn:se:his:diva-23434Test

المؤلفون: Lind, Ann-Marie, Sundlöf, Sofia

مصطلحات موضوعية: Diabetes mellitus type 1, adult, quality of life, dietary carbohydrates, carbohydrates., Diabetes mellitus typ 1, vuxna, livskvalitet, kolhydrater i kosten, kolhydrater.

الوصف: Background: Type 1 Diabetes is a disease that is present in all ages. A treatment with carbohydrate counting and flexible insulin dosing provides a freer diet and is used today in much of the world. Carbohydrate counting with flexible insulin dosing can improve the quality of life in people with diabetes. With support and training the nurse has an important role to support people in their self-care. Aim: To describe how adults with type 1 diabetes mellitus rated and felt their quality of life when using carbohydrate calculated insulin dose and to describe included studies' data collection methods. Method: Descriptive literature review of 13 articles. Literature searches were made in the databases PubMed and CINAHL. Main results: After participating in a structured training regarding carbohydrate counting with flexible insulin dosing rated and experienced the adults with type 1 diabetes, an increased quality of life with greater freedom to customize their diet according to their life situation. Their knowledge of diabetes increased, which gave them a better self-control and self-esteem leading to better self-care. The number of severe hypoglycemia and the fear of them decreased with a carbohydrate calculated insulin dose. Articles used validated questionnaires as data collection methods. Conclusion: Adults with type 1 diabetes, who participated in a structured education in carbohydrate counting with flexible insulin dosing increased their quality of life in both the short and long term and got a better understanding of the disease that gave better self-control and self-esteem leading to better self-care.
Bakgrund: Diabetes mellitus typ 1 är en sjukdom som finns i alla åldrar. En behandlingsmetod med kolhydraträkning och flexibel insulindosering ger en friare kosthållning och används idag i en stor del av världen. Kolhydraträkning med flexibel insulindosering kan förbättra livskvaliteten hos personer med diabetes. Med stöd och utbildning inom området har sjuksköterskan en viktig uppgift att stötta personerna i deras egenvård. Syfte: Att beskriva hur vuxna med diabetes mellitus typ 1 skattade och upplevde sin livskvalitet vid kolhydratberäknad insulindosering samt att beskriva inkluderade studiers datainsamlingsmetoder. Metod: Deskriptiv litteraturstudie av 13 artiklar. Litteratursökningar gjordes i databaserna PubMed och Cinahl. Huvudresultat: Efter deltagande i en strukturerad utbildning i kolhydraträkning med flexibel insulindosering skattade och upplevde vuxna med diabetes mellitus typ 1 en ökad livskvalitet med en ökad frihet att anpassa sin kost efter sin livssituation. Deras kunskaper om diabetessjukdomen ökade vilket gav dem en bättre självkontroll och självkänsla vilket ledde till bättre egenvård. Antalet svåra hypoglykemier och rädslan för dessa minskade med en kolhydratberäknad insulindosering. Artiklarna använde validerade frågeformulär som datainsamlingsmetod. Slutsats: Vuxna med diabetes mellitus typ 1 som deltagit i en strukturerad utbildning i kolhydraträkning med flexibel insulindosering ökade sin livskvalitet både på kort och lång sikt samt fick bättre kunskap om sjukdomen som gav bättre självkontroll och självkänsla vilket ledde till bättre egenvård.

وصف الملف: application/pdf

الإتاحة: http://urn.kb.se/resolve?urn=urn:nbn:se:hig:diva-21852Test

المؤلفون: Eduardo de Paula Miranda

مرشدي الرسالة: Ricardo Jordão Duarte, Katia Ramos Moreira Leite, Marcelo Lopes de Lima, Roberto Iglesias Lopes

المصدر: Biblioteca Digital de Teses e Dissertações da USPUniversidade de São PauloUSP.

مصطلحات موضوعية: Adulto, Antígeno CA-19- 9, Curva ROC, Diagnóstico, Hidronefrose, Lipocalinas, Marcadores biológicos, Microglobulina-2 beta, Molécula de lesão renal tipo 1, Obstrução ureteral, Adult, Beta 2-microglobulin, Biological markers, CA-19-9 antigen, Diagnosis, Hydronephrosis, Kidney injury molecule-1, Lipocalins, ROC curve, Ureteral obstruction

الوصف: INTRODUÇÃO E OBJETIVO: A estenose de junção ureteropélvica (EJUP) é importante causa de obstrução do trato urinário e pode levar a deterioração progressiva da função renal. Há espaço para o aprimoramento de novos métodos diagnósticos capazes de discriminar hidronefrose e uropatia obstrutiva. Acredita-se que os biomarcadores urinários podem fornecer indícios de lesão renal precoce na obstrução urinária. Neste contexto, KIM-1 pode elevar-se na urina por lesão tubular proximal, NGAL por lesão no túbulo proximal, distal ou alça de Henle, CA19-9 por produção excessiva no túbulo obstruído e ?2-microglobulina (beta2M) por injúria ao glomérulo ou ao túbulo proximal. O objetivo do presente estudo foi avaliar as propriedades diagnósticas dos biomarcadores urinários citados em adultos com EJUP, sendo o primeiro estudo na literatura a avaliar tais moléculas nesta população. MÉTODOS: Foram estudados de modo prospectivo pacientes consecutivos acima de 18 anos com diagnóstico de EJUP submetidos a pieloplastia videolaparoscópica de dezembro de 2013 a fevereiro de 2015. Foram excluídos do estudo pacientes com EJUP bilateral, rim contralateral patológico, EJUP em rim único, antecedentes de tratamento cirúrgico para estenose de JUP ou taxa de filtração glomerular inferior a 60 ml/min/1,73m2. Cada paciente forneceu quatro amostras de urina para medição de biomarcadores, uma no pré-operatório e outras com 1, 3 e 6 meses de seguimento pós-operatório. O grupo controle foi constituído por voluntários saudáveis sem hidronefrose à ultrassonografia. RESULTADOS: Foram incluídos 47 pacientes com idade média de 38,6 ± 12,7 anos (intervalo 19 a 64 anos), sendo 17 (36,2%) do sexo masculino e 30 (62,8%) do sexo feminino. O grupo controle foi composto por 40 indivíduos semelhantes ao grupo com EJUP no que concerne idade (p = 0,95) e sexo (p = 0,82). KIM-1 foi o marcador com melhores propriedades diagnósticas, apresentando área sob a curva (AUC) de 0,79 (95% CI 0,70 a 0,89). O NGAL, por sua vez, teve AUC de 0,71 (95% CI 0,61 a 0,83), CA19- 9 teve AUC de 0,70 (95% CI 0,60 a 0,81) e (beta2M) apresentou AUC de 0,61 (95% CI 0,50 a 0,73), sendo o único biomarcador com propriedades inadequadas neste cenário. O KIM-1 foi o marcador mais sensível com o ponto de corte 170,4 pg/mg de creatinina (sensibilidade 91,4%, especificidade 59,1%) e o CA 19-9 o mais específico para o ponto de corte de 51,3 U/mg de creatinina (sensibilidade 48,9%, especificidade 88,0%), enquanto o NGAL foi o que apresentou maior queda após desobstrução, com 90,0% dos pacientes apresentando clareamento superior a 50%. CONCLUSÕES: A avaliação dos biomarcadores urinários é útil no diagnóstico de obstrução em adultos com EJUP submetidos a pieloplastia videolaparoscópica. O KIM-1 foi o marcador mais sensível e o CA 19-9 o mais específico, enquanto o NGAL foi o que apresentou maior que com a desobstrução. Houve queda das concentrações dos marcadores após pieloplastia no período estudado. O papel exato dos biomarcadores urinários no cenário de obstrução em adultos deve ser mais amplamente investigado
INTRODUCTION AND OBJECTIVE: Ureteropelvic junction obstruction (UPJO) is an important cause of urinary tract obstruction and can lead to progressive deterioration of renal function. Thus the development of novel non-invasive methods capable of discriminating obstruction and hydronephrosis may be useful. Elevation of urinary biomarkers may provide early evidence of kidney damage in urinary obstruction. In this scenario, urinary concentrations of KIM-1 may be elevated following proximal tubular injury, while NGAL may increase as result of injury to proximal or distal tubule as well as to loop of Henle, CA19-9 after overproduction in the obstructed tubule and ?2 microglobulin (beta2M) after injury to the glomerulus or the proximal tubule. The aim of this study was to evaluate the diagnostic properties of these urinary biomarkers in adults with UPJO. METHODS: We prospectively studied consecutive patients older than 18 years diagnosed with UPJO undergoing laparoscopic pyeloplasty from December 2013 to February 2015 in our institution. Exclusion criteria included patients with bilateral UPJO, unilateral UPJO with contralateral pathologic kidney, solitary kidney, history of previous surgical treatment for UPJO or glomerular filtration rate below 60 ml/min/1,73m2. Each patient provided four voided urine samples for biomarker measurement, one at preoperative consultation and the others at 1, 3 and 6 months of postoperative follow-up. Healthy individuals with no hydronephrosis on ultrasound evaluation constituted our control group. RESULTS: We included 47 patients with a mean age of 38.6 ± 12.7 years (range 19-64 years), from which 17 (36.2%) were males and 30 (62.8%) were females. The control group consisted of 40 subjects with no statistical difference to the study group regarding age (p = 0.95) and gender (p = 0.82). KIM-1 had an area under the curve (AUC) of 0.79 (95% CI 0.70 to 0.89) and was the biomarker with the best diagnostic properties. CA19-9 had an AUC of 0.70 (95% CI 0.60 to 0.81), NGAL had an AUC of 0.71 (95% CI 0.61 to 0.83) and beta2M had an AUC of 0.61 (95% CI 0.50 to 0.73). KIM-1 was the most sensitive marker with a cutoff of 170.4 pg/mg creatinine (sensitivity 91.4%, specificity 59.1%) whereas CA 19-9 as the most specific one, displaying a cutoff of 51.3 U/mg creatinine (sensitivity 48.9%, specificity 88.0%). NGAL showed the greatest decrease in urinary concentrations after pyeloplasty, in which 90.0% of patients had a clearance greater than 50% in comparison to preoperative values. CONCLUSIONS: The evaluation of urinary biomarkers is useful in the assessment of UPJO in adults undergoing laparoscopic pyeloplasty. Urinary concentrations of CA 19-9, NGAL and KIM-1 were elevated in patients with UPJO and significantly decreased after pyeloplasty. The exact role of those biomarkers in the setting of obstruction in adults should be further evaluated

الإتاحة: http://www.teses.usp.br/teses/disponiveis/5/5153/tde-20052016-160232Test/

المؤلفون: Suárez Robles, Moisés Alberto

المساهمون: Universidad Nacional de Colombia, Ruiz Ariza, Edgar Alberto

مصطلحات موضوعية: 03 Obras enciclopédicas generales / Encyclopedias and books of facts, 1 Filosofía y psicología / Philosophy and psychology, 5 Ciencias naturales y matemáticas / Science, 57 Ciencias de la vida, Biología / Life sciences, biology, 6 Tecnología (ciencias aplicadas) / Technology, 61 Ciencias médicas, Medicina / Medicine and health, Limitantes, Ortodoncia, Adulto, Rehabilitación, Oral, Limiting, Orthodontic, Adult, Rehabilitation

الوصف: La siguiente revisión narrativa de la literatura identifica y organiza en una secuencia lógica los criterios utilizados para considerar exitoso el tratamiento ortodóntico en el adulto y los principales factores que limitan la consecución de los objetivos planteados al inicio del tratamiento ortodóntico en el adulto y cómo estas limitaciones afectan la restauración de la función oclusal deteriorada. METODOLOGIA: Se realizó una revisión bibliográfica intencionada en las bases de datos Wiley, Pubmed, Scielo, Science Direct, Cochrane Library con palabras claves (limiting, orthodontic, adult), relacionándolas con cada uno de los capítulos principales elegidos para la discusión (limitantes Sistémicos, funcionales, del diente y su periodonto, económico-social) obteniendo información científica actualizada acerca de cada tópico. RESULTADOS: En total fueron seleccionados 100 artículos que se incluyeron como sustento bibliográfico para enriquecer la discusión y la presentación de resultados. CONCLUSIONES: existen limitaciones en el tratamiento ortodóntico del adulto que afectan la restauración de la oclusión perdida, las cuales pueden resultar muy fuertes en comparación con las encontradas en pacientes que no han alcanzado su pico de crecimiento final. ; Abstract. The following narrative review of the literature identified and organized in a logical sequence the criteria used to consider successful orthodontic treatment in adults and major factors limiting the achievement of the objectives set at the beginning of orthodontic treatment in adults and how these limitations affect the restoration of impaired occlusal function. METHODOLOGY: intentional literature review in the databases Wiley, Pubmed, Scielo, Science Direct, Cochrane Library with keywords (limiting, orthodontic, adult) relating them to each of the main chapters chosen for discussion (Systemic limiting was performed, functional tooth and periodontium, economic and social) to obtain updated information on each topic scientific information. RESULTS: In total ...

وصف الملف: application/pdf

العلاقة: Universidad Nacional de Colombia Sede Bogotá Facultad de Odontología Departamento de Salud Oral; Departamento de Salud Oral; Suárez Robles, Moisés Alberto (2016) Limitantes ortodónticas en el tratamiento restaurativo del paciente adulto, revisión narrativa de la literatura. Otra thesis, Universidad Nacional de Colombia-Sede Bogotá.; https://repositorio.unal.edu.co/handle/unal/58902Test; http://bdigital.unal.edu.co/55945Test/

الإتاحة: https://repositorio.unal.edu.co/handle/unal/58902Test
http://bdigital.unal.edu.co/55945Test/

المؤلفون: GONÇALVES, Alessandra Rocha

مرشدي الرسالة: HADLER, Maria Claret Costa Monteiro

المصدر: Biblioteca Digital de Teses e Dissertações da UFGUniversidade Federal de GoiásUFG.

مصطلحات موضوعية: adulto, diabetes mellitus, diabetes mellitus tipo 1, doenças cardiovasculares, fatores de risco, hemoglobina A glicada, adult, type 1 diabetes mellitus, cardiovascular diseases, risk factors, glycosylated hemoglobin A, CNPQ::CIENCIAS DA SAUDE::NUTRICAO

الوصف: Made available in DSpace on 2014-07-29T15:23:45Z (GMT). No. of bitstreams: 1 dissertacao setembro alessandra.pdf: 495425 bytes, checksum: 575e13fa35e5d2b8ee0bc6d97a6bdeae (MD5) Previous issue date: 2012-06-29
Objective: To evaluate the nutritional status, the glycemic control and the prevalence of cardiovascular risk factors in patients with type 1 diabetes mellitus (T1DM), attended at the nutrition and endocrinology outpatient clinic of the Goiânia Geral Hospital (GGH). Methodology: a cross-sectional study conducted from March to August/2011, with the following inclusion criteria: consolidated diagnosis of the disease for at least six months, age ranging from 19 to 60 years. Fifty-two patients were selected and interviewed, and 44 came to the clinic for collection of biological material. Personal, socioeconomic and biochemical data were collected. Fasting glucose (FG), glycated hemoglobin (HbA1c), lipid profile and microalbuminuria (MA) were determined. MA and HbA1c were determined by immunoturbidimetry and FG and lipid profile by the enzymatic colorimetric method using a Labmax Plenno apparatus. After collecting the material, physical assessment was performed by three trained interviewers who collected measurements of weight, height, waist circumference and blood pressure measurement, following recommendations from the literature. The following risk factors were evaluated: hypertension, dyslipidemia, general obesity (BMI- body mass index), abdominal obesity (WC- waist circumference), glycated hemoglobin, microalbuminuria, family history of type 2 diabetes, and smoking. The cutoffs recommended by the American Diabetes Association (ADA) were adopted. Statistical analysis was performed using the Statistical Package for the Social Sciences SPSS 18.0. Results: The average age of patients was 30.6 ± 7.4 years, the time of diagnosis was 9.9 ± 7.1 years and median education was 12 years. The HbA1c was inadequate in 90.9% of the patients and 38.6% of the patients were found to be overweight (n=17). Most cases of inadequacy of BMI, WC and total cholesterol (TC) involved females. The prevalence of hypertension was 38.6% (n=17) and the prevalence of dyslipidemia was 63.6% (n=28). The prevalence of inappropriate LDL, HDL, cholesterol and triglyceride levels was 39.5%, 25%, 22.7%, and 22.7%, respectively. The prevalence of MA was 72%. Conclusion: most patients presented unsatisfactory glucose control. The prevalence of overweight and hypertension, of altered lipid profile, and microalbuminuria was high.
Objetivo: Avaliar o estado nutricional, o controle glicêmico e a prevalência dos fatores de risco cardiovasculares em pacientes adultos com diabetes mellitus tipo 1 (DM1), atendidos no ambulatório de nutrição e endocrinologia do Hospital Geral de Goiânia (HGG). Metodologia: Estudo transversal, realizado entre março e agosto/2011, cujos critérios de inclusão foram: diagnóstico consolidado da doença há pelo menos seis meses, idade maior ou igual a dezenove anos e menor que sessenta anos. Foram selecionados e entrevistados 52 pacientes, dos quais 44 compareceram para coleta de material biológico. Coletou-se dados clínicos, socioeconômicos e bioquímicos. Foram realizados exames de glicemia de jejum (GJ), hemoglobina glicada (HbA1c), perfil lipídico e microalbuminúria (MA). O método utilizado para dosar HbA1c E MA foi a Imunoturbidimetria, realizada no aparelho Labmax Plenno. Os exames de glicemia de jejum e lipidograma também foram realizados no mesmo equipamento, pelo método enzimático-colorimétrico (oxidase/ peroxidase). Após a coleta de material, foi realizada avaliação física por três entrevistadores treinados que coletaram medidas de peso, altura, circunferência da cintura e aferição da pressão arterial, seguindo recomendações da literatura. Foram avaliados os seguintes fatores de risco cardiovasculares: hipertensão arterial, dislipidemia, obesidade geral (IMC- Índice de massa corporal), obesidade abdominal (CC- circunferência da cintura), hemoglobina glicada, microalbuminúria, história familiar de diabetes tipo 2 e tabagismo. Foram adotados os pontos de corte recomendados pela American Diabetes Association (ADA). A análise estatística foi realizada no programa Statistical Package for the Social Sciences- SPSS 18.0. Resultados: A idade média dos pacientes foi de 30,6±7,4 anos, o tempo de diagnóstico foi de 9,9 ±7,1 anos e a mediana da escolaridade foi de 12 anos. A HbA1c estava inadequada em 90,9% dos pacientes. O excesso de peso foi observado em 38,6% dos pacientes (n=17). A maior prevalência de inadequação do IMC, CC e colesterol total (CT) foi associada ao sexo feminino. A prevalência de hipertensão arterial foi de 38,6% (n=17) e de dislipidemia foi de 63,6% (n=28) dos pacientes. As prevalências de inadequação do LDL, HDL, colesterol e triglicerídeos foram de 38,6%, 25%, 22,7%, 22,7%, respectivamente. A prevalência de MA foi de 72%. Conclusão: A maioria dos pacientes apresentou controle glicêmico insatisfatório. Foi alta a prevalência de excesso de peso e de inadequação da pressão arterial, do perfil lipídico, e microalbuminúria.

وصف الملف: application/pdf

الإتاحة: http://repositorio.bc.ufg.br/tede/handle/tde/1481Test

المؤلفون: Foss, Johanna, Löfgren, Erika

مصطلحات موضوعية: Health, Well-Being, Type 1 Diabetes, Adult, Hälsa, Välbefinnande, Typ 1 Diabetes Mellitus, Vuxna

الوصف: Studiens syfte var att beskriva upplevelse av hälsa och välbefinnande hos vuxna personer med Typ 1 Diabetes Mellitus (T1DM). Jämförelser gjordes även mellan kön och åldrar. Urvalet gjordes från medlemmar i Gävleborgs Diabetesförbund och bestod utav 56 personer (kvinnor n 30, män n 26) med ett åldersspann mellan 19-76. Använd datainsamlingsmetod var en förkortad och översatt version av mätinstrumentet Ryff’s Psychological Well being Scale. Enkäten bestod utav 18 frågor inom de 6 dimensioner som instrumentet består utav: Självacceptans, positiva relationer med andra, autonomi, levnadskontroll, meningen med livet samt personlig utveckling. Resultatet visade att gruppen T1DM skattade sig generellt högt inom hälsa och välbefinnande men lägst inom dimensionen autonomi och högst inom positiva relationer med andra. Statistisk signifikans framkom vid jämförelse av åldersgrupperna 19-39 och 40-60 inom dimensionerna meningen med livet samt personlig utveckling där gruppen 19-39 skattade sig högst inom båda dimensionerna. Statistisk signifikans kunde även påvisas vid jämförelse av samtliga 3 åldersgrupper inom dimensionen meningen med livet där gruppen 19-39 skattade sig högst och 61+ lägst. Slutligen kunde statistisk signifikans påvisas mellan könen inom dimensionen positiva relationer med andra där kvinnorna skattade sig högre än männen. Vidare forskning behövs inom området som rör personer med T1DM för att förbättra allmän hälsa och välbefinnande.
The aim of this study was to describe the experience health and well-being among adults with type 1 diabetes mellitus (T1DM). Comparison was made regarding sex and age. The sample was taken from Gävleborgs Diabetesförbund and consisted of 56 persons (women n 30, men n 26) aged between 19 and 76. Health and well-being was measured with a shortened translated 18 item version of the instrument Ryff’s Psychological Well being Scale. The 18 items describe the 6 dimensions of the instrument which it is built on: self-acceptance, positive relationships with others, autonomy, environmental mastery, purpose in life and personal growth. The result shows that the group T1DM estimated themselves generally high in health and well-being but lowest in the dimension autonomy and highest in positive relations with others. Statistical significance was shown in comparison between age groups 19-39 and 40-60 in the dimensions purpose in life and personal growth, where the group 19-39 estimated themselves highest in both dimensions. Statistical significance was also demonstrated in comparison between all age groups in the dimension purpose in life, where the group 19-39 estimated themselves highest and 61+ lowest. Finally, statistical significance was shown between the sexes in the dimension positive relations with others, where the women estimated themselves higher than the men. Further research is needed in the area that involves persons with T1DM to improve their general health and well-being.

وصف الملف: application/pdf

الإتاحة: http://urn.kb.se/resolve?urn=urn:nbn:se:hig:diva-7910Test

المؤلفون: GONÇALVES, Alessandra Rocha

المساهمون: HADLER, Maria Claret Costa Monteiro, CPF:26078317172, http://lattes.cnpq.br/6754793957094104Test

مصطلحات موضوعية: adulto, diabetes mellitus, diabetes mellitus tipo 1, doenças cardiovasculares, fatores de risco, hemoglobina A glicada, adult, type 1 diabetes mellitus, cardiovascular diseases, risk factors, glycosylated hemoglobin A, CNPQ::CIENCIAS DA SAUDE::NUTRICAO

الوصف: Objective: To evaluate the nutritional status, the glycemic control and the prevalence of cardiovascular risk factors in patients with type 1 diabetes mellitus (T1DM), attended at the nutrition and endocrinology outpatient clinic of the Goiânia Geral Hospital (GGH). Methodology: a cross-sectional study conducted from March to August/2011, with the following inclusion criteria: consolidated diagnosis of the disease for at least six months, age ranging from 19 to 60 years. Fifty-two patients were selected and interviewed, and 44 came to the clinic for collection of biological material. Personal, socioeconomic and biochemical data were collected. Fasting glucose (FG), glycated hemoglobin (HbA1c), lipid profile and microalbuminuria (MA) were determined. MA and HbA1c were determined by immunoturbidimetry and FG and lipid profile by the enzymatic colorimetric method using a Labmax Plenno apparatus. After collecting the material, physical assessment was performed by three trained interviewers who collected measurements of weight, height, waist circumference and blood pressure measurement, following recommendations from the literature. The following risk factors were evaluated: hypertension, dyslipidemia, general obesity (BMI- body mass index), abdominal obesity (WC- waist circumference), glycated hemoglobin, microalbuminuria, family history of type 2 diabetes, and smoking. The cutoffs recommended by the American Diabetes Association (ADA) were adopted. Statistical analysis was performed using the Statistical Package for the Social Sciences SPSS 18.0. Results: The average age of patients was 30.6 ± 7.4 years, the time of diagnosis was 9.9 ± 7.1 years and median education was 12 years. The HbA1c was inadequate in 90.9% of the patients and 38.6% of the patients were found to be overweight (n=17). Most cases of inadequacy of BMI, WC and total cholesterol (TC) involved females. The prevalence of hypertension was 38.6% (n=17) and the prevalence of dyslipidemia was 63.6% (n=28). The prevalence of inappropriate LDL, HDL, ...

وصف الملف: application/pdf

العلاقة: GONÇALVES, Alessandra Rocha. Type 1 Diabetes Mellitus: glycemic control and cardiovascular risk factors in adults. 2012. 95 f. Dissertação (Mestrado em Ciencias da Saude) - Universidade Federal de Goiás, Goiânia, 2012.; http://repositorio.bc.ufg.br/tede/handle/tde/1481Test; http://repositorio.bc.ufg.br/handle/ri/8202Test

الإتاحة: http://repositorio.bc.ufg.br/tede/handle/tde/1481Test
http://repositorio.bc.ufg.br/handle/ri/8202Test

المؤلفون: Azage, Meron Y., B.S.

مصطلحات موضوعية: Genetics, Neurofibromatosis Type 1 (NF1), Adult, Fractures, Bone, Bone Mineral Density (BMD), Calcium

الوصف: About 30-50% of patients with Neurofibromatosis Type 1 (NF1) have disease involving the skeletal system. Osteoporosis and low bone density are common findings; however increased rate of fractures in patients with NF1 has not yet been established in a well-designed clinical study. The purpose of this study is to compare the prevalence of fractures between adults with NF1 and unaffected controls including unaffected siblings/spouses of these patients. We hypothesized that the NF1 cohort will have fracture rates that are higher than unaffected controls. A retrospective questionnaire was administered to 38 adults with NF1 and 36 unaffected adults. Participants were asked to report fractures that occurred during their lifetime as well as in the past 10 years. The number of fractures, the bone location, age of participant when the fracture occurred, cause of fracture (such as trauma), time for healing, treatment and complications were assessed. We stratified fracture rates in cases and controls for age and sex, and statistically adjusted for other risk factors such as ethnicity, body mass index (BMI), tobacco use, menopause status, level of physical activity and dietary calcium intake. While adults with NF1 had higher 10 year fracture rate than controls, the difference did not reach statistical significant. Given the relatively small sample size in this study, collection of additional data is warranted. Improving our understanding of skeletal phenotype of NF1 may change clinical management, improve standard of care of patients and inform future drug trials for bone disease.

الإتاحة: http://rave.ohiolink.edu/etdc/view?acc_num=ucin1337352142Test