Presentation_1_Physical Activity and Sleep/Wake Behavior, Anthropometric, and Metabolic Profile in Pediatric Narcolepsy Type 1.PDF

التفاصيل البيبلوغرافية
العنوان: Presentation_1_Physical Activity and Sleep/Wake Behavior, Anthropometric, and Metabolic Profile in Pediatric Narcolepsy Type 1.PDF
المؤلفون: Marco Filardi, Fabio Pizza, Elena Antelmi, Paolo Pillastrini, Vincenzo Natale, Giuseppe Plazzi
سنة النشر: 2018
المجموعة: Frontiers: Figshare
مصطلحات موضوعية: Neurology and Neuromuscular Diseases, Neurogenetics, narcolepsy type 1, children, physical activity, actigraphy, weight control
الوصف: Objectives: Regular physical activity is routinely recommended in children and adolescents suffering from narcolepsy type 1 (NT1), but controlled studies analyzing its influence on sleep/wake behavior, metabolic, and anthropometric profile in pediatric NT1 are lacking. Methods: Fifty consecutive drug-naïve NT1 children and adolescents were assessed through actigraphic, clinical, and metabolic evaluations. Patients were compared with respect to their engagement in leisure-time physical activities (LTPA): patients engaged in LTPA (n = 30) and patients not engaged (No-LTPA, n = 20), respectively. Results: LTPA patients presented lower BMI, with different BMI categories distribution and higher HDL cholesterol, when compared with No-LTPA subjects. Increased night-sleep duration, higher sleep quality, and reduction of nap frequency were documented through actigraphy in LTPA subjects. Subjective sleepiness, as measured by ESS-CHAD, was also lower in LTPA subjects while cataplexy frequency proved similar between the two groups. Discussion: In pediatric NT1 patients, regular engagement in LTPA is associated with significant differences on sleepiness, anthropometric and metabolic profile and objectively assessed sleep/wake behavior. Engagement in LTPA is beneficial and should be strongly encouraged in pediatric NT1 patients.
نوع الوثيقة: conference object
اللغة: unknown
العلاقة: https://figshare.com/articles/presentation/Presentation_1_Physical_Activity_and_Sleep_Wake_Behavior_Anthropometric_and_Metabolic_Profile_in_Pediatric_Narcolepsy_Type_1_PDF/7006925Test
DOI: 10.3389/fneur.2018.00707.s001
الإتاحة: https://doi.org/10.3389/fneur.2018.00707.s001Test
https://figshare.com/articles/presentation/Presentation_1_Physical_Activity_and_Sleep_Wake_Behavior_Anthropometric_and_Metabolic_Profile_in_Pediatric_Narcolepsy_Type_1_PDF/7006925Test
حقوق: CC BY 4.0
رقم الانضمام: edsbas.76778A7
قاعدة البيانات: BASE