المؤلفون: Madeline Alizadeh, Alyssa Schledwitz, Kunrong Cheng, Jean-Pierre Raufman

مصطلحات موضوعية: Physiology, Exercise Physiology, Nutritional Physiology, Reproduction, Cell Physiology, Systems Physiology, Animal Physiology - Biophysics, Animal Physiology - Cell, Animal Physiology - Systems, Comparative Physiology, Physiology not elsewhere classified, colon (C26) carcinoma, muscarinic receptor (subtypes), acetylcholine, G protein-coupled receptors, Wnt/β-catenin signaling pathway

العلاقة: https://figshare.com/articles/presentation/Presentation_1_Mechanistic_Clues_Provided_by_Concurrent_Changes_in_the_Expression_of_Genes_Encoding_the_M1_Muscarinic_Receptor_-Catenin_Signaling_Proteins_and_Downstream_Targets_in_Adenocarcinomas_of_the_Colon_PPTX/19366022Test

الإتاحة: https://doi.org/10.3389/fphys.2022.857563.s001Test
https://figshare.com/articles/presentation/Presentation_1_Mechanistic_Clues_Provided_by_Concurrent_Changes_in_the_Expression_of_Genes_Encoding_the_M1_Muscarinic_Receptor_-Catenin_Signaling_Proteins_and_Downstream_Targets_in_Adenocarcinomas_of_the_Colon_PPTX/19366022Test

المؤلفون: ombretta paladino, Arianna Moranda, Carla Falugi

المساهمون: Paladino, Ombretta, Moranda, Arianna, Falugi, Carla

مصطلحات موضوعية: muscarinic signalling, AChE, neurotoxic pesticides, chick embryo

وصف الملف: ELETTRONICO

العلاقة: ispartofbook:Buznikov Memorial Readings; Buznikov Memorial Readings - Russian Academy of Sciences; firstpage:1; lastpage:3; numberofpages:3; http://hdl.handle.net/11567/1046313Test

الإتاحة: http://hdl.handle.net/11567/1046313Test

المؤلفون: Cáceres Cardoso, Juan Pablo, González Amaya, Jhon Alex, Vargas Oviedo, Diana Marcela

المساهمون: González Amaya, Jhon Alex 0001441638, Vargas Oviedo, Diana Marcela 0001561144, González Amaya, Jhon Alex Nn1JSDMAAAAJ, Cáceres Cardoso, Juan Pablo 0000-0002-6659-0555, González Amaya, Jhon Alex 0000-0002-0605-9877, Vargas Oviedo, Diana Marcela 0000-0002-5904-6287, Cáceres Cardoso, Juan Pablo Juan_Caceres_Cardoso, Vargas Oviedo, Diana Marcela Diana-Vargas-45, Semilleros de Investigación UNAB

المصدر: Cáceres, J. P., González, J. A. & Vargas, D. M. (2021). Diseño y optimización In silico de un nuevo análogo del bromuro de glucopirrolato con potencial actividad farmacológica para el tratamiento de la EPOC. Recuperado de: http://hdl.handle.net/20.500.12749/20559Test

مصطلحات موضوعية: Congresses, Conferences, Seminars, Pharmaceutical chemistry, Glycopyrrolate bromide, Muscarinic receptors, COPD, Investigation, Molecular docking, ADME predictio, Physicochemical characteristics, Química farmacéutica, Bromuro de glucopirrolato, Receptores muscarínicos, EPOC, Investigación, Congresos, Conferencias, Seminarios, Docking molecular, Predicción ADME, Características fisicoquímicas

جغرافية الموضوع: Bucaramanga (Santander, Colombia), UNAB Campus Bucaramanga

الوقت: 2021

وصف الملف: application/pdf

العلاقة: http://hdl.handle.net/20.500.12749/20557Test; Abad Santos, F., Novalbos, J., Gallego Sandin, S., & Galvez Mugica, M. A. (2005). Regulación del tono bronquial en la enfermedad pulmonar obstructiva crónica (EPOC): Papel de los receptores muscarínicos. Anales De Medicina Interna, 20(4), 45-49.; Abd-Ella, A., Stankiewicz, M., Mikulska, K., Nowak, W., Pennetier, C., Goulu, M., . . . List, O. (2015). The repellent DEET potentiates carbamate effects via insect muscarinic receptor interactions: An alternative strategy to control insect vector-borne diseases. PloS One, 10(5), e0126406.; American Thoracic Society. (2005). Enfermedad pulmonar obstructiva crónica (EPOC). Retrieved from https://www.thoracic.org/patients/patient-resources/resources/spanish/chronic-obstructivepulmonary-disease-copd.pdfTest; Allmendinger, T., Bixel, D., Clarke, A., Di Geronimo, L., Fredy, J., Manz, M., . . . Valentekovic, D. (2012). Carry over of impurities: A detailed exemplification for glycopyrrolate (NVA237). Organic Process Research & Development, 16(11), 1754-1769. doi:10.1021/op3001788; Bandaru, S., Hema Prasad, M., Jyothy, A., Nayarisseri, A., & Yadav, M. (2013). Binding modes and pharmacophoric features of muscarinic antagonism and β2 agonism (MABA) conjugates. Current Topics in Medicinal Chemistry, 13(14), 1650-1655.; Carrasco, E. (2013). Avances en la terapia inhalatoria de las vías aéreas en asma y EPOC. Revista Chilena De Enfermedades Respiratorias, 29(4), 204-215.; Corzo, R. G., Montoya, L. G., Cifuentes, R. H., Encorrada, M. L., & Cruz, R. P. (2005). Enfermedad pulmonar obstructiva crónica. Medicina Crítica, 16(6), 201-210.; K American Academy of Family Physicians. (2012). Enfermedad pulmonar obstructiva crónica. Retrieved from https://es.familydoctor.org/condicion/enfermedad-pulmonar-obstructiva-cronicaTest/; Liu, H., Hofmann, J., Fish, I., Schaake, B., Eitel, K., Bartuschat, A., . . . Hübner, H. (2018). Structureguided development of selective M3 muscarinic acetylcholine receptor antagonists. Proceedings of the National Academy of Sciences, 115(47), 12046-12050.; Martínez-Aguilar, N. E., Vargas-Camaño, M. E., Hernández-Pliego, R. R., Chaia-Semerena, G. M., & del Rosario Pérez-Chavira, M. (2017). Immunopathology of chronic obstructive pulmonary disease inmunopatología de la enfermedad pulmonar obstructiva crónica. Rev Alerg Mex, 64(3), 327-346.; Méndez-Domínguez, N., Vidal-Rosado, E., Vázquez-Madariaga, C., Falcón-Solís, E., & BriceñoSouza, E. (2020). Epidemiological analysis of chronic obstructive pulmonary disease mortality in the state of yucatan in 2017. NCT Neumología Y Cirugía De Tórax, 79(1), 31-36.; Min Salud. (2014). Guía de práctica clínica para el diagnóstico, tratamiento e inicio de la rehabilitación psicosocial de los adultos con esquizofrenia (29th ed.). Bogotá: Min Salud. Retrieved from file:///home/and/Documentos/Semestre%207%20QF/Farmacología%202/GPC-EsquizofreniaCompleta.pdf; Montes de Oca, M. (2011). Recomendaciones para el diagnóstico y tratamiento de la enfermedad pulmonar obstructiva crónica (EPOC). Retrieved from www.alatorax.org; Rahaghi, F. F., & Miravitlles, M. (2017). Long-term clinical outcomes following treatment with alpha 1-proteinase inhibitor for COPD associated with alpha-1 antitrypsin deficiency: A look at the evidence. Respiratory Research, 18(1), 1-9.; Regalado, J., Pérez-Padilla, R., Sansores, R., Páramo Ramírez, J. I., Brauer, M., Paré, P., & Vedal, S. (2006). The effect of biomass burning on respiratory symptoms and lung function in rural mexican women. American Journal of Respiratory and Critical Care Medicine, 174(8), 901-905.; Roca, C. (2018). Técnicas computacionales aplicadas al descubrimiento de neurofármacos.; Rovina, N., Koutsoukou, A., & Koulouris, N. G. (2013). Inflammation and immune response in COPD: Where do we stand? Mediators of Inflammation, 2013; Salvi, S., & Barnes, P. J. (2010). Is exposure to biomass smoke the biggest risk factor for COPD globally? Chest, 138(1), 3-6.; Segovia, M., Alés, E., Montes, M. A., Bonifas, I., Jemal, I., Lindau, M., . . . de Toledo, G. A. (2010). Push-and-pull regulation of the fusion pore by synaptotagmin-7. Proceedings of the National Academy of Sciences, 107(44), 19032-19037.; Silinsky, E. M. (2008). Selective disruption of the mammalian secretory apparatus enhances or eliminates calcium current modulation in nerve endings. Proceedings of the National Academy of Sciences, 105(17), 6427-6432.; Soto, M. F., & Torres, J. S. (2005). Structure and function of the acetylcholine of muscarinical and nicotinical type. Revista Mexicana De Neurociencia, 6(4), 315-326; Torres, M. A. G., Pérez, A. M., García, M. F. O., Isunza, P. S., García, M. A. S., & Loza-Mejía, M. A. (2017). Diseño de ligandos a los receptores muscarínicos M2 y M3 como potenciales fármacos para el tratamiento de la enfermedad pulmonar obstructiva crónica (EPOC). Sociedad Química De México, , 1-6.; Velásquez, B. L., Fernández, P. L., González, A. M., Hernández, I. L., Cerro, J. C. L., Sánchez, M. A. M., . . . Pérez, A. P. (2009). Farmacología básica y clínica Médica Panamericana.; Wu, W., Buchwald, P., Mori, N., Ji, F., Wu, J., & Bodor, N. (2005). Pharmacokinetic and pharmacodynamic evaluations of the zwitterionic metabolite of a new series of N-substituted soft anticholinergics. Pharmaceutical Research, 22(12), 2035-2044.; Yamashita, Y., Tanaka, K., Yamakawa, N., Asano, T., Kanda, Y., Takafuji, A., . . . Mizushima, T. (2019). Chemical modification-mediated optimisation of bronchodilatory activity of mepenzolate, a muscarinic receptor antagonist with anti-inflammatory activity. Bioorganic & Medicinal Chemistry, 27(15), 3339-3346.; http://hdl.handle.net/20.500.12749/20559Test; instname:Universidad Autónoma de Bucaramanga - UNAB; reponame:Repositorio Institucional UNAB; repourl:https://repository.unab.edu.coTest

الإتاحة: https://doi.org/20.500.12749/20559Test
https://hdl.handle.net/20.500.12749/20559Test

المؤلفون: Spiteri, Jessica, Grech, Louise, Montefort, Stephen, Azzopardi, Lilian M.

مصطلحات موضوعية: Lungs -- Diseases, Obstructive -- Treatment -- Malta, Obstructive -- Malta -- Case studies, Obstructive -- Patients -- Medical care, Obstructive -- Complications, Muscarinic Antagonists

العلاقة: Spiteri, J., Grech, L., Montefort, S., & Azzopardi, L. M. (2018, October). Chronic obstructive pulmonary disease exacerbations: a hospital-based study. Poster session presented at the 2018 ACCP Global Conference on Clinical Pharmacy, Seattle, Washington, USA.; https://www.um.edu.mt/library/oar/handle/123456789/48766Test

الإتاحة: https://www.um.edu.mt/library/oar/handle/123456789/48766Test

المؤلفون: Hanson Ho, Matt De Both, Ashley Siniard, Sasha Sharma, James H. Notwell, Michelle Wallace, Dino P. Leone, Amy Nguyen, Eric Zhao, Hannah Lee, Daniel Zwilling, Kimberly R. Thompson, Steven P. Braithwaite, Matthew Huentelman, Thomas Portmann

مصطلحات موضوعية: Cell Biology, Neuroscience, Cellular Nervous System, Central Nervous System, Cellular Interactions (incl. Adhesion, Matrix, Cell Wall), Protein Trafficking, single-cell RNA sequencing, fluorescence-activated cell sorting, striatal medium spiny neurons, basal ganglia, dopamine receptors, Cholinergic Receptor Muscarinic 4

العلاقة: https://figshare.com/articles/presentation/Presentation_1_A_Guide_to_Single-Cell_Transcriptomics_in_Adult_Rodent_Brain_The_Medium_Spiny_Neuron_Transcriptome_Revisited_pdf/6540854Test

الإتاحة: https://doi.org/10.3389/fncel.2018.00159.s001Test
https://figshare.com/articles/presentation/Presentation_1_A_Guide_to_Single-Cell_Transcriptomics_in_Adult_Rodent_Brain_The_Medium_Spiny_Neuron_Transcriptome_Revisited_pdf/6540854Test

المؤلفون: Hanna Trebesova, Guendalina Olivero, Mario Marchi, Massimo Grilli

المساهمون: Trebesova, Hanna, Olivero, Guendalina, Marchi, Mario, Grilli, Massimo

مصطلحات موضوعية: KLVFF, Beta-amyloid, synaptosome, Alzheimer’s disease, nicotinic receptor, muscarinic receptor, dopamine release, noradrenaline release

وصف الملف: STAMPA

العلاقة: ispartofbook:NC; FENS; http://hdl.handle.net/11567/1094498Test

الإتاحة: http://hdl.handle.net/11567/1094498Test

المؤلفون: Hanna Trebesova, Guendalina Olivero, Mario Marchi, Massimo Grilli

المساهمون: Trebesova, Hanna, Olivero, Guendalina, Marchi, Mario, Grilli, Massimo

مصطلحات موضوعية: KLVFF, β-amyloid, synaptosomes, Alzheimer’s disease, nicotinic receptors, muscarinic receptors, dopamine release, noradrenaline release

وصف الملف: STAMPA

العلاقة: ispartofbook:NC; 41°CONGRESSO NAZIONALE DELLA SOCIETÀ ITALIANA DI FARMACOLOGIA; https://hdl.handle.net/11567/1107836Test

الإتاحة: https://hdl.handle.net/11567/1107836Test

المؤلفون: Sommerlatte, S, Pitann, S, Rana, M, Marschner, G, Heidecke, H, Humrich, J, Lange, T, Lamprecht, P, Müller, A, Cabral-Marques, O, Riemekasten, G

المصدر: 44. Kongress der Deutschen Gesellschaft für Rheumatologie (DGRh); 30. Jahrestagung der Deutschen Gesellschaft für Orthopädische Rheumatologie (DGORh); 26. Jahrestagung der Gesellschaft für Kinder- und Jugendrheumatologie (GKJR); 20160831-20160903; Frankfurt am Main; DOCER.24 /20160829/

مصطلحات موضوعية: autoantibodies, muscarinic acetylcholine receptor, systemic lupus erythematosus, systemic sclerosis, chronic fatigue syndrom, ddc: 610

العلاقة: http://dx.doi.org/10.3205/16dgrh055Test; http://nbn-resolving.de/urn:nbn:de:0183-16dgrh0551Test; http://www.egms.de/en/meetings/dgrh2016/16dgrh055.shtmlTest

الإتاحة: https://doi.org/10.3205/16dgrh055Test
http://nbn-resolving.de/urn:nbn:de:0183-16dgrh0551Test
http://www.egms.de/en/meetings/dgrh2016/16dgrh055.shtmlTest

المؤلفون: A. De Min, U. Holzgrabe, K. Mohr, C. Matera, C. Dallanoce, M. De Amici

المساهمون: A. De Min, C. Matera, C. Dallanoce, U. Holzgrabe, M. De Amici, K. Mohr

مصطلحات موضوعية: muscarinic, dualsteric, allosteric, orthosteric, protean, acetylcholine, mAChR, dynamic binding, bitopic ligand, cholinergic, Settore BIO/10 - Biochimica, Settore BIO/11 - Biologia Molecolare, Settore BIO/14 - Farmacologia, Settore CHIM/08 - Chimica Farmaceutica

العلاقة: GPCRs: Beyond Structure Towards Therapy; http://hdl.handle.net/2434/329759Test; https://www.biochemistry.org/Events/tabid/379/View/Posters/Page/3/MeetingNo/SA173/Default.aspxTest

الإتاحة: http://hdl.handle.net/2434/329759Test
https://www.biochemistry.org/Events/tabid/379/View/Posters/Page/3/MeetingNo/SA173/Default.aspxTest

المؤلفون: C. Matera, C. Dallanoce, M. Quadri, M. De Amici, U. Holzgrabe, E. Barocelli, K. Mohr

المساهمون: C. Matera, C. Dallanoce, M. Quadri, U. Holzgrabe, E. Barocelli, K. Mohr, M. De Amici

مصطلحات موضوعية: GPCR, allosteric, orthosteric, dualsteric, bitopic, muscarinic receptor, M1, M2, M3, M4, M5, iperoxo, biased signaling, signalling selectivity, allosteric modulator, dualsteric ligand, selective agonists, Settore CHIM/08 - Chimica Farmaceutica, Settore BIO/14 - Farmacologia, Settore BIO/11 - Biologia Molecolare

العلاقة: GPCR Spring Conference; http://hdl.handle.net/2434/239144Test; http://eventia.estaticos.econgres.es/2014_SpingConference/abstracts_gpcr.pdfTest

الإتاحة: http://hdl.handle.net/2434/239144Test
http://eventia.estaticos.econgres.es/2014_SpingConference/abstracts_gpcr.pdfTest