كتاب
Type VII Secretion Systems in Gram-Positive Bacteria
| العنوان: | Type VII Secretion Systems in Gram-Positive Bacteria |
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| المؤلفون: | Bottai, Daria, Gröschel, Matthias I., Brosch, Roland |
| المساهمون: | Bagnoli, Fabio, Rappuoli, Rino |
| المصدر: | Bottai , D , Gröschel , M I & Brosch , R 2017 , Type VII Secretion Systems in Gram-Positive Bacteria . in F Bagnoli & R Rappuoli (eds) , Protein and Sugar Export and Assembly in Gram-positive Bacteria . vol. 404 , Current Topics in Microbiology and Immunology , vol. 404 , Springer , pp. 235-265 . https://doi.org/10.1007/82_2015_5015Test |
| بيانات النشر: | Springer |
| سنة النشر: | 2017 |
| المجموعة: | University of Groningen research database |
| مصطلحات موضوعية: | PE-PGRS PROTEINS, MYCOBACTERIUM-TUBERCULOSIS VIRULENCE, INTRACELLULAR STAPHYLOCOCCUS-AUREUS, RESPONSE REGULATOR DEGU, BACILLUS-SUBTILIS, ESAT-6 SECRETION, ESX-1 SECRETION, PATHOGENIC MYCOBACTERIA, CALMETTE-GUERIN, OUTER-MEMBRANE |
| الوصف: | Bacterial secretion systems are sophisticated molecular machines that fulfil a wide range of important functions, which reach from export/secretion of essential proteins or virulence factors to the implication in conjugation processes. In contrast to the widely distributed Sec and Twin Arginine Translocation (TAT) systems, the recently identified ESX/type VII systems show a more restricted distribution and are typical for mycobacteria and other high-GC Actinobacteria. Similarly, type VII-like secretion systems have been described in low-GC Gram-positive bacteria belonging to the phylum Firmicutes. While the most complex organization of type VII secretion systems currently known is found in slow-growing mycobacteria, which harbour up to 5 chromosomal-encoded systems (ESX-1 to ESX-5), much simpler organization is reported for type VII-like systems in Firmicutes. In this chapter, we describe common and divergent features of type VII- and type VII-like secretion pathways and also comment on their biological key roles, many of which are related to species-/genus-specific host-pathogen interactions and/or virulence mechanisms. |
| نوع الوثيقة: | book part |
| اللغة: | English |
| ردمك: | 978-3-319-56012-0 3-319-56012-3 |
| العلاقة: | https://research.rug.nl/en/publications/fdfc672b-24e4-4dc7-9ded-ffe7ae85840aTest; urn:ISBN:978-3-319-56012-0 |
| DOI: | 10.1007/82_2015_5015 |
| الإتاحة: | https://doi.org/10.1007/82_2015_5015Test https://hdl.handle.net/11370/fdfc672b-24e4-4dc7-9ded-ffe7ae85840aTest https://research.rug.nl/en/publications/fdfc672b-24e4-4dc7-9ded-ffe7ae85840aTest |
| حقوق: | info:eu-repo/semantics/closedAccess |
| رقم الانضمام: | edsbas.7C2FE005 |
| قاعدة البيانات: | BASE |
| ردمك: | 9783319560120 3319560123 |
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| DOI: | 10.1007/82_2015_5015 |