كتاب
Application of Base Editor-Mediated Genome Editing in Mouse Retina
| العنوان: | Application of Base Editor-Mediated Genome Editing in Mouse Retina |
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| المؤلفون: | Wu, Jun, Cho, Chang Sik, Jo, Dong Hyun, Kim, Jeong Hun |
| المساهمون: | Jo, Dong Hyun, Kim, Jeong Hun |
| بيانات النشر: | Humana Press, Inc. |
| سنة النشر: | 2023 |
| المجموعة: | Seoul National University: S-Space |
| مصطلحات موضوعية: | Base editor, Intravitreal injection, Subretinal injection |
| الوصف: | Base editor is a newly developed genome editing technology that enables conversion of single nucleotides without DNA double-strand breaks (DSB) and maintains a low rate of insertion-deletion (INDEL) errors. With these flexibility and safety, base editor has been widely used in many fields, including inherited retinal disease. The majority of retinal genome editing requires intravitreal and subretinal injection delivery of the therapeutic vector in order to transduce the target cells. Here, we provide an application guide of base editor as performed in the mouse retina. ; N ; 1 |
| نوع الوثيقة: | book part article in journal/newspaper |
| اللغة: | unknown |
| تدمد: | 1064-3745 |
| العلاقة: | Methods in molecular biology (Clifton, N.J.), Vol.2606, pp.179-188; https://hdl.handle.net/10371/191453Test; 2-s2.0-85145492563; 181422 |
| DOI: | 10.1007/978-1-0716-2879-9_14 |
| الإتاحة: | https://doi.org/10.1007/978-1-0716-2879-9_14Test https://hdl.handle.net/10371/191453Test |
| رقم الانضمام: | edsbas.1F5280C2 |
| قاعدة البيانات: | BASE |
| تدمد: | 10643745 |
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| DOI: | 10.1007/978-1-0716-2879-9_14 |