كتاب إلكتروني
Human Challenge Studies in Endemic Settings
| العنوان: | Human Challenge Studies in Endemic Settings |
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| المؤلفون: | Jamrozik, Euzebiusz, Selgelid, Michael J. |
| بيانات النشر: | Springer Nature; Springer, 2021. |
| سنة النشر: | 2021 |
| المجموعة: | Books Imported or submitted locally |
| Original Material: | 6c6992af-b843-4f46-859c-f6e9998e40d5 |
| مصطلحات موضوعية: | Bioethics, Infectious Diseases, Vaccine, Development and Health, Moral Philosophy and Applied Ethics, Internal Medicine, Pharmacology, Development Studies, human challenge studies, Open Access, capacity building in low-income countries, capacity building in middle-income countries, malariotherapy, intentional infection, ethics of challenge studies, challenge studies in endemic settings, challenge studies and vulnerable populations, Falciparum malaria challenge studies in Africa, Infectious & contagious diseases, Immunology, Development studies, bic Book Industry Communication::P Mathematics & science::PS Biology, life sciences::PSA Life sciences: general issues::PSAD Bio-ethics, bic Book Industry Communication::M Medicine::MJ Clinical & internal medicine::MJC Diseases & disorders::MJCJ Infectious & contagious diseases, bic Book Industry Communication::M Medicine::MJ Clinical & internal medicine::MJC Diseases & disorders::MJCM Immunology, bic Book Industry Communication::G Reference, information & interdisciplinary subjects::GT Interdisciplinary studies::GTF Development studies |
| الوصف: | This open access book provides an extensive review of ethical and regulatory issues related to human infection challenge studies, with a particular focus on the expansion of this type of research into endemic settings and/or low- and middle-income countries (LMICs). Human challenge studies (HCS) involve the intentional infection of research participants, and this type of research is rapidly increasing in frequency worldwide. HCS are widely considered to be an especially promising approach to vaccine development, including for pathogens endemic to LMICs. However, challenge studies are sometimes controversial and raise complex ethical issues, some of which are especially salient in endemic and/or LMIC settings. Informed by qualitative interviews with experts in infectious diseases and bioethics, this book highlights areas of ethical consensus and controversy concerning this kind of research. As the first volume to focus on ethical issues associated with human challenge studies, it sets the agenda for further work in this important area of global health research; contributes to current debates in research ethics; and aims to inform regulatory policy and research practice. Insofar as it focuses on HCS in (endemic) settings where diseases are present and/or widespread, much of the analysis provided here is directly relevant to HCS involving pandemic diseases including COVID19. |
| نوع الوثيقة: | book |
| وصف الملف: | application/pdf |
| اللغة: | English |
| ردمك: | 978-3-030-41480-1 3-030-41480-9 |
| العلاقة: | SpringerBriefs in Ethics |
| DOI: | 10.1007/978-3-030-41480-1 |
| الوصول الحر: | https://library.oapen.org/handle/20.500.12657/41732Test |
| حقوق: | URL: http://creativecommons.org/licenses/by/4.0Test/ |
| ملاحظات: | ONIX_20200921_9783030414801_89 https://www.springer.com/9783030414801Test |
| رقم الانضمام: | edsoap.20.500.12657.41732 |
| قاعدة البيانات: | OAPEN Library |
| ردمك: | 9783030414801 3030414809 |
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| DOI: | 10.1007/978-3-030-41480-1 |