المؤلفون: Rasco, Drew W, Medina, Theresa, Corrie, Pippa, Pavlick, Anna C, Middleton, Mark R, Lorigan, Paul, Hebert, Chris, Plummer, Ruth, Larkin, James, Agarwala, Sanjiv S, Daud, Adil I, Qiu, Jiaheng, Bozon, Viviana, Kneissl, Michelle, Barry, Elly, Olszanski, Anthony J

المصدر: Cancer chemotherapy and pharmacology. 92(1)

مصطلحات موضوعية: Humans, Neoplasms, Melanoma, Skin Neoplasms, Neoplasms, Second Primary, Proto-Oncogene Proteins B-raf, Mitogen-Activated Protein Kinase Kinases, Protein Kinase Inhibitors, Maximum Tolerated Dose, Adult, BRAF, Pan-RAF inhibitor, Phase 1, Tovorafenib, Clinical Trials and Supportive Activities, Clinical Research, Cancer, 6.1 Pharmaceuticals, Evaluation of treatments and therapeutic interventions, Pharmacology and Pharmaceutical Sciences, Oncology & Carcinogenesis

وصف الملف: application/pdf

الوصول الحر: https://escholarship.org/uc/item/6jq463hgTest

المؤلفون: Watson, Robert A, Ye, Weiyu, Taylor, Chelsea A, Jungkurth, Elsita, Cooper, Rosalin, Tong, Orion, James, Tim, Shine, Brian, Hofer, Monika, Jenkins, Damian, Pell, Robert, Ieremia, Eleni, Jones, Stephanie, Maldonado-Perez, David, Roberts, Ian S D, Coupe, Nicholas, Middleton, Mark R, Payne, Miranda J, Fairfax, Benjamin P

المساهمون: Oxford Biomedical Research, Oxford CRUK Cancer Centre, Wellcome Trust, National Institute for Health Research, Balliol Jowett Society, Cancer Research UK, Engineering and Physical Sciences Research Council

المصدر: Journal for ImmunoTherapy of Cancer ; volume 12, issue 4, page e008151 ; ISSN 2051-1426

الإتاحة: https://doi.org/10.1136/jitc-2023-008151Test

المؤلفون: Larkin, James, Marais, Richard, Porta, Nuria, Gonzalez de Castro, David, Parsons, Lisa, Messiou, Christina, Stamp, Gordon, Thompson, Lisa, Edmonds, Kim, Sarker, Sarah, Banerji, Jane, Lorigan, Paul, Evans, Thomas R. Jeffry, Corrie, Pippa, Marshall, Ernest, Middleton, Mark R., Nathan, Paul, Nicholson, Steve, Ottensmeier, Christian, Plummer, Ruth, Bliss, Judith, Valpione, Sara, Turajlic, Samra

المساهمون: Novartis AG, Cancer Research UK

المصدر: Cell Reports Medicine ; volume 5, issue 3, page 101435 ; ISSN 2666-3791

مصطلحات موضوعية: General Biochemistry, Genetics and Molecular Biology

الإتاحة: https://doi.org/10.1016/j.xcrm.2024.101435Test
https://api.elsevier.com/content/article/PII:S2666379124000582?httpAccept=text/xmlTest
https://api.elsevier.com/content/article/PII:S2666379124000582?httpAccept=text/plainTest

المؤلفون: Nicholson, Brian D, Oke, Jason, Virdee, Pradeep S, Harris, Dean A, O'Doherty, Catherine, Park, John Es, Hamady, Zaed, Sehgal, Vinay, Millar, Andrew, Medley, Louise, Tonner, Sharon, Vargova, Monika, Engonidou, Lazarina, Riahi, Kaveh, Luan, Ying, Hiom, Sara, Kumar, Harpal, Nandani, Harit, Kurtzman, Kathryn N, Yu, Ly-Mee, Freestone, Clare, Pearson, Sarah, Hobbs, Fd Richard, Perera, Rafael, Middleton, Mark R

وصف الملف: text

العلاقة: https://eprints.soton.ac.uk/485379/1/PIIS1470204523002772.pdfTest; Nicholson, Brian D, Oke, Jason, Virdee, Pradeep S, Harris, Dean A, O'Doherty, Catherine, Park, John Es, Hamady, Zaed, Sehgal, Vinay, Millar, Andrew, Medley, Louise, Tonner, Sharon, Vargova, Monika, Engonidou, Lazarina, Riahi, Kaveh, Luan, Ying, Hiom, Sara, Kumar, Harpal, Nandani, Harit, Kurtzman, Kathryn N, Yu, Ly-Mee, Freestone, Clare, Pearson, Sarah, Hobbs, Fd Richard, Perera, Rafael and Middleton, Mark R (2023) Multi-cancer early detection test in symptomatic patients referred for cancer investigation in England and Wales (SYMPLIFY): a large-scale, observational cohort study. Lancet Oncology, 24 (7), 733-743. (doi:10.1016/S1470-2045(23)00277-2 ).

الإتاحة: https://doi.org/10.1016/S1470-2045Test(23)00277-2
https://eprints.soton.ac.uk/485379Test/
https://eprints.soton.ac.uk/485379/1/PIIS1470204523002772.pdfTest

المؤلفون: Carroll, Thomas M., Chadwick, Joseph A., Owen, Richard P., White, Michael J., Kaplinsky, Joseph, Peneva, Iliana, Frangou, Anna, Xie, Phil F., Chang, Jaeho, Roth, Andrew, Amess, Bob, James, Sabrina A., Rei, Margarida, Fuchs, Hannah S., McCann, Katy J., Omiyale, Ayo O., Jacobs, Brittany-Amber, Lord, Simon R., Norris-Bulpitt, Stewart, Dobbie, Sam T., Griffiths, Lucinda, Ramirez, Kristen Aufiero, Ricciardi, Toni, Macri, Mary J., Ryan, Aileen, Venhaus, Ralph R., Van den Eynde, Benoit, Karydis, Ioannis, Schuster-Böckler, Benjamin, Middleton, Mark R., Lu, Xin

المساهمون: UCL - SSS/DDUV/GECE - Génétique cellulaire

المصدر: Cancer Cell, Vol. 41, no.7, p. 1222-1241.e7 (2023)

مصطلحات موضوعية: Cancer Research, Oncology

العلاقة: boreal:278087; http://hdl.handle.net/2078.1/278087Test; urn:ISSN:1535-6108

الإتاحة: https://doi.org/10.1016/j.ccell.2023.06.006Test
http://hdl.handle.net/2078.1/278087Test

المؤلفون: Hamid, Omid, Hassel, Jessica C., Shoushtari, Alexander N., Meier, Friedegund, Bauer, Todd M., Salama, April K.S., Kirkwood, John M., Ascierto, Paolo A., Lorigan, Paul C., Mauch, Cornelia, Orloff, Marlana, Evans, Thomas R.Jeffry, Holland, Chris, Edukulla, Ramakrishna, Abedin, Shaad E., Middleton, Mark R.

المصدر: Hamid , O , Hassel , J C , Shoushtari , A N , Meier , F , Bauer , T M , Salama , A K S , Kirkwood , J M , Ascierto , P A , Lorigan , P C , Mauch , C , Orloff , M , Evans , T R J , Holland , C , Edukulla , R , Abedin , S E & Middleton , M R 2023 , ' Tebentafusp in combination with durvalumab and/or tremelimumab in patients with metastatic cutaneous melanoma : A phase 1 study ' , Journal ....

مصطلحات موضوعية: Immune Checkpoint Inhibitors, Immunotherapy, Melanoma, T-Lymphocytes

الإتاحة: https://doi.org/10.1136/jitc-2023-006747Test
https://research.manchester.ac.uk/en/publications/a22c4b91-7500-4140-b016-d3a434e88583Test
http://www.scopus.com/inward/record.url?scp=85161095486&partnerID=8YFLogxKTest

المؤلفون: Hamid, Omid, Hassel, Jessica C., Shoushtari, Alexander N., Meier, Friedegund, Bauer, Todd M., Salama, April K.S., Kirkwood, John M., Ascierto, Paolo A., Lorigan, Paul C., Mauch, Cornelia, Orloff, Marlana, Evans, Thomas R. Jeffry, Holland, Chris, Edukulla, Ramakrishna, Abedin, Shaad E., Middleton, Mark R.

وصف الملف: text

العلاقة: https://eprints.gla.ac.uk/300986/1/300986.pdfTest; Hamid, O. et al. (2023) Tebentafusp in combination with durvalumab and/or tremelimumab in patients with metastatic cutaneous melanoma: a phase 1 study. Journal for ImmunoTherapy of Cancer , 11(6), e006747. (doi:10.1136/jitc-2023-006747 ) (PMID:37286303) (PMCID:PMC10254987)

الإتاحة: https://doi.org/10.1136/jitc-2023-006747Test
https://eprints.gla.ac.uk/300986Test/
https://eprints.gla.ac.uk/300986/1/300986.pdfTest

المؤلفون: Woodcock, Victoria K., Chen, Ji‐Li, Purshouse, Karin, Butcher, Chrissie, Collins, Linda, Haddon, Caroline, Verrall, Gillian, Elhussein, Leena, Roberts, Corran, Tarlton, Andrea, Rei, Margarida, Napolitani, Giorgio, Salio, Mariolina, Middleton, Mark R., Cerundolo, Vincenzo, Crew, Jeremy, Protheroe, Andrew S.

المساهمون: University of Oxford, NIHR Oxford Biomedical Research Centre, Merck Sharp and Dohme, Cancer Research UK

المصدر: BJUI Compass ; volume 4, issue 3, page 322-330 ; ISSN 2688-4526 2688-4526

الإتاحة: https://doi.org/10.1002/bco2.220Test

المؤلفون: Zhu, Winston M, Middleton, Mark R

المساهمون: Roche, AstraZeneca, Novartis, Millenium, Immunocore, Eisai, Merck, Rigontec, BiolineRx, Array Biopharma, Pfizer, Kineta, Replimune

المصدر: Immunotherapy Advances ; volume 3, issue 1 ; ISSN 2732-4303

الإتاحة: https://doi.org/10.1093/immadv/ltad013Test
https://academic.oup.com/immunotherapyadv/article-pdf/3/1/ltad013/51174253/ltad013.pdfTest

المؤلفون: Juric, Dejan, Rodon, Jordi, Tabernero, Josep, Janku, Filip, Burris, Howard A, Schellens, Jan HM, Middleton, Mark R, Berlin, Jordan, Schuler, Martin, Gil-Martin, Marta, Rugo, Hope S, Seggewiss-Bernhardt, Ruth, Huang, Alan, Bootle, Douglas, Demanse, David, Blumenstein, Lars, Coughlin, Christina, Quadt, Cornelia, Baselga, José

المصدر: Journal of Clinical Oncology. 36(13)

مصطلحات موضوعية: Biomedical and Clinical Sciences, Clinical Sciences, Oncology and Carcinogenesis, Cancer, Breast Cancer, Patient Safety, 6.1 Pharmaceuticals, 6.2 Cellular and gene therapies, Evaluation of treatments and therapeutic interventions, Administration, Oral, Adult, Aged, Aged, 80 and over, Breast Neoplasms, Class I Phosphatidylinositol 3-Kinases, Dose-Response Relationship, Drug, Drug Administration Schedule, Female, Humans, Middle Aged, Thiazoles, Treatment Outcome, Oncology & Carcinogenesis, Oncology and carcinogenesis

وصف الملف: application/pdf

الوصول الحر: https://escholarship.org/uc/item/5km780mwTest