دورية أكاديمية
Interstitial Lung Disease Worsens Short- and Long-Term Outcomes of Systemic Rheumatic Disease Patients Admitted to the ICU: A Multicenter Study
| العنوان: | Interstitial Lung Disease Worsens Short- and Long-Term Outcomes of Systemic Rheumatic Disease Patients Admitted to the ICU: A Multicenter Study |
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| المؤلفون: | Banuls, Lorrain, Vanoverschelde, Juliette, Garnier, Fanny, Amalric, Matthieu, Jaber, Samir, Charbit, Jonathan, Chalard, Kevin, Mourad, Marc, Benchabane, Nacim, Benomar, Racim, Besnard, Noemie, Daubin, Delphine, Brunot, Vincent, Klouche, Kada, Larcher, R. |
| المساهمون: | Centre Hospitalier Régional Universitaire Montpellier (CHRU Montpellier), Hôpital Lapeyronie Montpellier (CHU), Hôpital Arnaud de Villeneuve CHRU Montpellier, Physiologie & médecine expérimentale du Cœur et des Muscles U 1046 (PhyMedExp), Institut National de la Santé et de la Recherche Médicale (INSERM)-Université de Montpellier (UM)-Centre National de la Recherche Scientifique (CNRS), Hôpital Gui de Chauliac CHU Montpellier, Université de Montpellier (UM) |
| المصدر: | ISSN: 2077-0383 ; Journal of Clinical Medicine ; https://hal.science/hal-03163541Test ; Journal of Clinical Medicine, 2021, 10 (5), pp.1037. ⟨10.3390/jcm10051037⟩. |
| بيانات النشر: | HAL CCSD MDPI |
| سنة النشر: | 2021 |
| المجموعة: | Université de Montpellier: HAL |
| مصطلحات موضوعية: | Intensive care unit, Interstitial lung disease, Systemic rheumatic disease, Mortality, Outcome, [SDV.MHEP.RSOA]Life Sciences [q-bio]/Human health and pathology/Rhumatology and musculoskeletal system, [SDV.MHEP.PSR]Life Sciences [q-bio]/Human health and pathology/Pulmonology and respiratory tract, [SDV.SPEE]Life Sciences [q-bio]/Santé publique et épidémiologie |
| الوصف: | International audience ; Critically ill patients with systemic rheumatic diseases (SRDs) have a fair prognosis, while those with interstitial lung disease (ILD) have a poorer outcome. However, the prognosis of SRD patients with ILD admitted to the intensive care unit (ICU) remains unclear. We conducted a case–control study to investigate the outcomes of critically ill SRD-ILD patients. Consecutive SRD-ILD patients admitted to five ICUs from January 2007 to December 2017 were compared to SRD patients without ILD. Mortality rates were compared between groups, and prognostic factors were then identified. One hundred and forty critically ill SRD patients were included in the study. Among the 70 patients with SRD–ILD, the SRDs were connective tissue diseases (56%), vasculitis (29%), sarcoidosis (13%), and spondylarthritis (3%). Patients were mainly admitted for acute exacerbation of SRD-ILD (36%) or infection (34%). ICU, in-hospital, and one-year mortality rates in SRD-ILD patients were higher than in SRD patients without ILD (n = 70): 40% vs. 16% (p < 0.01), 49% vs. 19% (p < 0.01), and 66% vs. 40% (p < 0.01), respectively. Hypoxemia, high sequential organ failure assessment (SOFA) score, and admission for ILD acute exacerbation were associated with ICU mortality. In conclusion, ILD worsened the outcomes of SRD patients admitted to the ICU. Admissions related to SRD-ILD acute exacerbation and the severity of the acute respiratory failure were associated with ICU mortality |
| نوع الوثيقة: | article in journal/newspaper |
| اللغة: | English |
| ردمك: | 978-0-00-628310-2 0-00-628310-1 |
| العلاقة: | info:eu-repo/semantics/altIdentifier/pmid/33802364; hal-03163541; https://hal.science/hal-03163541Test; https://hal.science/hal-03163541v2/documentTest; https://hal.science/hal-03163541v2/file/jcm-10-01037.pdfTest; PUBMED: 33802364; PUBMEDCENTRAL: PMC7959321; WOS: 000628310100001 |
| DOI: | 10.3390/jcm10051037 |
| الإتاحة: | https://doi.org/10.3390/jcm10051037Test https://hal.science/hal-03163541Test https://hal.science/hal-03163541v2/documentTest https://hal.science/hal-03163541v2/file/jcm-10-01037.pdfTest |
| حقوق: | http://creativecommons.org/licenses/byTest/ ; info:eu-repo/semantics/OpenAccess |
| رقم الانضمام: | edsbas.2A0004D2 |
| قاعدة البيانات: | BASE |
| ردمك: | 9780006283102 0006283101 |
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| DOI: | 10.3390/jcm10051037 |