المؤلفون: Gitelman, Stephen E, Bundy, Brian N, Ferrannini, Ele, Lim, Noha, Blanchfield, J Lori, DiMeglio, Linda A, Felner, Eric I, Gaglia, Jason L, Gottlieb, Peter A, Long, S Alice, Mari, Andrea, Mirmira, Raghavendra G, Raskin, Philip, Sanda, Srinath, Tsalikian, Eva, Wentworth, John M, Willi, Steven M, Krischer, Jeffrey P, Bluestone, Jeffrey A, Group, Gleevec Trial Study, Barr, Mayalin, Buchanan, Jeanne, Cabbage, Joanne, Coleman, Peter, De La Vega, Monica, Evans-Molina, Carmella, Ferrara, Christine, Healy, Felicity, Higgins, Laurie, Hildinger, Megan, Jenkins, Margaret, Bryant, Nora Kayton, Kinderman, Amanda, Koshy, Nisha, Kost, Brianne, Krishfield, Suzanne, Kucheruk, Olena, Lindsley, Karen, Mantravadi, Manasa, Mesfin, Shelley, Michels, Aaron, Migre, Mary Ellen, Minnock, Pantea, Mohammed-Nur, Elham, Nelson, Jennifer, Nursing, Ashvin, O'Donnell, Ryan, Olivos, Diana, Parker, Melissa, Redl, Leanne, Reed, Nicole, Resnick, Brittany, Sayre, Peter, Serti, Elisavet, Sims, Emily, Smith, Karen, Soppe, Carol, Stuart, Fiona, Szubowicz, Sarah, Tansey, Michel, Terrell, Jennifer, Tersey, Sarah, Torok, Christine, Watson, Kelly, Wesch, Rebecca, Willi, Steven, Woerner, Stephanie

المصدر: The Lancet Diabetes & Endocrinology. 9(8)

مصطلحات موضوعية: Biomedical and Clinical Sciences, Clinical Sciences, Clinical Trials and Supportive Activities, Prevention, Autoimmune Disease, Clinical Research, Diabetes, 6.1 Pharmaceuticals, Evaluation of treatments and therapeutic interventions, Metabolic and endocrine, Adolescent, Adult, Biomarkers, Blood Glucose, Diabetes Mellitus, Type 1, Double-Blind Method, Female, Follow-Up Studies, Humans, Imatinib Mesylate, Male, Middle Aged, Prognosis, Protein Kinase Inhibitors, Young Adult, Gleevec Trial Study Group, Medical Biochemistry and Metabolomics, Public Health and Health Services, Clinical sciences, Medical biochemistry and metabolomics

وصف الملف: application/pdf

الوصول الحر: https://escholarship.org/uc/item/2hr6m8qwTest

المؤلفون: Redondo, Maria J, Steck, Andrea K, Sosenko, Jay, Anderson, Mark, Antinozzi, Peter, Michels, Aaron, Wentworth, John M, Atkinson, Mark A, Pugliese, Alberto, Geyer, Susan, Group, the Type 1 Diabetes TrialNet Study

المصدر: Diabetes Care. 41(12)

مصطلحات موضوعية: Biomedical and Clinical Sciences, Health Sciences, Prevention, Genetics, Autoimmune Disease, Nutrition, Diabetes, Aetiology, 2.1 Biological and endogenous factors, Metabolic and endocrine, Adolescent, Adult, Antibody Specificity, Autoantibodies, Autoimmunity, Child, Child, Preschool, Cohort Studies, Diabetes Mellitus, Type 1, Disease Progression, Female, Gene Frequency, Genetic Predisposition to Disease, Humans, Infant, Male, Middle Aged, Obesity, Overweight, Polymorphism, Single Nucleotide, Risk Factors, Transcription Factor 7-Like 2 Protein, Young Adult, Type 1 Diabetes TrialNet Study Group, Medical and Health Sciences, Endocrinology & Metabolism, Biomedical and clinical sciences, Health sciences

وصف الملف: application/pdf

الوصول الحر: https://escholarship.org/uc/item/8qs5877sTest

المؤلفون: Redondo, Maria J, Geyer, Susan, Steck, Andrea K, Sosenko, Jay, Anderson, Mark, Antinozzi, Peter, Michels, Aaron, Wentworth, John, Xu, Ping, Pugliese, Alberto

المصدر: Diabetes Care. 41(2)

مصطلحات موضوعية: Biomedical and Clinical Sciences, Clinical Sciences, Diabetes, Prevention, Autoimmune Disease, Clinical Research, Nutrition, Genetics, 2.1 Biological and endogenous factors, Aetiology, Metabolic and endocrine, Adolescent, Adult, Alleles, Child, Child, Preschool, Cohort Studies, Diabetes Mellitus, Type 1, Female, Genetic Heterogeneity, Genetic Predisposition to Disease, Humans, Male, Middle Aged, Phenotype, Polymorphism, Single Nucleotide, Transcription Factor 7-Like 2 Protein, Young Adult, Type 1 Diabetes TrialNet Study Group, Medical and Health Sciences, Endocrinology & Metabolism, Biomedical and clinical sciences, Health sciences

وصف الملف: application/pdf

الوصول الحر: https://escholarship.org/uc/item/4795706dTest

المؤلفون: Michels, Aaron W, Landry, Laurie G, McDaniel, Kristen A, Yu, Liping, Campbell-Thompson, Martha, Kwok, William W, Jones, Kenneth L, Gottlieb, Peter A, Kappler, John W, Tang, Qizhi, Roep, Bart O, Atkinson, Mark A, Mathews, Clayton E, Nakayama, Maki

المصدر: Diabetes. 66(3)

مصطلحات موضوعية: Diabetes, Autoimmune Disease, 2.1 Biological and endogenous factors, Aetiology, Metabolic and endocrine, Adolescent, Autoantigens, C-Peptide, CD4-Positive T-Lymphocytes, Child, Diabetes Mellitus, Type 1, Female, HLA-DQ Antigens, HLA-DR Antigens, Humans, Insulin, Insulin-Secreting Cells, Islets of Langerhans, Peptide Fragments, Proinsulin, Protein Precursors, Receptors, Antigen, T-Cell, Young Adult, Medical and Health Sciences, Endocrinology & Metabolism

وصف الملف: application/pdf

الوصول الحر: https://escholarship.org/uc/item/3hj3w3zrTest

المؤلفون: Yeh, Wen-I, Seay, Howard R, Newby, Brittney, Posgai, Amanda L, Moniz, Filipa Botelho, Michels, Aaron, Mathews, Clayton E, Bluestone, Jeffrey A, Brusko, Todd M

مصطلحات موضوعية: Biomedical and Clinical Sciences, Immunology, Autoimmune Disease, Genetics, Diabetes, Biotechnology, 5.2 Cellular and gene therapies, Development of treatments and therapeutic interventions, Metabolic and endocrine, Inflammatory and immune system, type 1 diabetes, regulatory T cells, T cell receptor, avidity, suppression mechanisms, adoptive cellular therapies, antigen-specific T cells, glutamic acid decarboxylase 65, Medical Microbiology, Biochemistry and cell biology

وصف الملف: application/pdf

الوصول الحر: https://escholarship.org/uc/item/1vp8p9khTest

المؤلفون: Haller, Michael J, Gitelman, Stephen E, Gottlieb, Peter A, Michels, Aaron W, Perry, Daniel J, Schultz, Andrew R, Hulme, Maigan A, Shuster, Jonathan J, Zou, Baiming, Wasserfall, Clive H, Posgai, Amanda L, Mathews, Clayton E, Brusko, Todd M, Atkinson, Mark A, Schatz, Desmond A

المصدر: Diabetes. 65(12)

مصطلحات موضوعية: Prevention, Diabetes, Clinical Research, Clinical Trials and Supportive Activities, Metabolic and endocrine, Good Health and Well Being, Adolescent, Adult, Antilymphocyte Serum, Area Under Curve, C-Peptide, CD4-Positive T-Lymphocytes, CD56 Antigen, CD8-Positive T-Lymphocytes, Child, Diabetes Mellitus, Type 1, Female, Forkhead Transcription Factors, Granulocyte Colony-Stimulating Factor, Humans, Immunologic Factors, Killer Cells, Natural, Male, Middle Aged, Monocytes, Polyethylene Glycols, Receptors, CXCR3, Receptors, IgG, Recombinant Proteins, T-Lymphocyte Subsets, T-Lymphocytes, Regulatory, Young Adult, Medical and Health Sciences, Endocrinology & Metabolism

وصف الملف: application/pdf

الوصول الحر: https://escholarship.org/uc/item/80s9w221Test

المؤلفون: Landry, Laurie G., Anderson, Amanda M., Russ, Holger A., Yu, Liping, Kent, Sally C, Atkinson, Mark A., Mathews, Clayton E., Michels, Aaron W., Nakayama, Maki

المساهمون: Diabetes Center of Excellence, Department of Medicine, Division of Diabetes

المصدر: Frontiers in endocrinology ; 12 ; 622647

مصطلحات موضوعية: T cell receptors, antigens, epitopes, islets, preproinsulin, type 1 diabetes, Endocrine System Diseases, Endocrinology, Diabetes, and Metabolism, Immune System Diseases, Nutritional and Metabolic Diseases

العلاقة: Link to Article in PubMed; Landry LG, Anderson AM, Russ HA, Yu L, Kent SC, Atkinson MA, Mathews CE, Michels AW, Nakayama M. Proinsulin-Reactive CD4 T Cells in the Islets of Type 1 Diabetes Organ Donors. Front Endocrinol (Lausanne). 2021 Mar 25;12:622647. doi:10.3389/fendo.2021.622647. PMID: 33841327; PMCID: PMC8027116. Link to article on publisher's site; 1664-2392 (Linking); http://hdl.handle.net/20.500.14038/41832Test; https://escholarship.umassmed.edu/cgi/viewcontent.cgi?article=5664&context=oapubs&unstamped=1Test; https://escholarship.umassmed.edu/oapubs/4633Test; oapubs/4633

الإتاحة: https://doi.org/10.3389/fendo.2021.622647Test
https://doi.org/20.500.14038/41832Test
https://hdl.handle.net/20.500.14038/41832Test
https://escholarship.umassmed.edu/cgi/viewcontent.cgi?article=5664&context=oapubs&unstamped=1Test
https://escholarship.umassmed.edu/oapubs/4633Test

المؤلفون: Haller, Michael J, Gitelman, Stephen E, Gottlieb, Peter A, Michels, Aaron W, Rosenthal, Stephen M, Shuster, Jonathan J, Zou, Baiming, Brusko, Todd M, Hulme, Maigan A, Wasserfall, Clive H, Mathews, Clayton E, Atkinson, Mark A, Schatz, Desmond A

المصدر: Journal of Clinical Investigation. 125(1)

مصطلحات موضوعية: Biomedical and Clinical Sciences, Clinical Sciences, Immunology, Clinical Research, Clinical Trials and Supportive Activities, Autoimmune Disease, Diabetes, Pediatric, Evaluation of treatments and therapeutic interventions, 6.1 Pharmaceuticals, Development of treatments and therapeutic interventions, 5.1 Pharmaceuticals, Metabolic and endocrine, Adolescent, Adult, Antilymphocyte Serum, C-Peptide, Child, Diabetes Mellitus, Type 1, Drug Combinations, Female, Glycated Hemoglobin, Granulocyte Colony-Stimulating Factor, Humans, Hypoglycemic Agents, Insulin, Insulin-Secreting Cells, Male, Middle Aged, Polyethylene Glycols, Single-Blind Method, Treatment Outcome, Young Adult, Medical and Health Sciences, Biological sciences, Biomedical and clinical sciences, Health sciences

وصف الملف: application/pdf

الوصول الحر: https://escholarship.org/uc/item/62k8452dTest

المؤلفون: Nakayama, Maki, McDaniel, Kristen, Fitzgerald-Miller, Lisa, Carol, Kiekhaefer, Snell-Bergeona, Janet K., Davidson, Howard W., Rewers, Marian, Yu, Liping, Gottlieb, Peter, Kappler, John W., Michels, Aaron

المصدر: Proceedings of the National Academy of Sciences of the United States of America, 2015 Apr 01. 112(14), 4429-4434.

الوصول الحر: https://www.jstor.org/stable/26462505Test

المؤلفون: Li Zhang, Crawford, Frances, Yu, Liping, Michels, Aaron, Nakayama, Maki, Davidson, Howard W., Kappler, John W., Eisenbarth, George S.

المصدر: Proceedings of the National Academy of Sciences of the United States of America, 2014 Feb . 111(7), 2656-2661.

الوصول الحر: https://www.jstor.org/stable/23768943Test