دورية أكاديمية
A comparison of conventional surgery, transcatheter aortic valve replacement, and sutureless valves in 'real-world' patients with aortic stenosis and intermediate- to high-risk profile Read at the 95th Annual Meeting of the American Association for Thoracic Surgery, Seattle, Washington, April 25-29, 2015
| العنوان: | A comparison of conventional surgery, transcatheter aortic valve replacement, and sutureless valves in 'real-world' patients with aortic stenosis and intermediate- to high-risk profile Read at the 95th Annual Meeting of the American Association for Thoracic Surgery, Seattle, Washington, April 25-29, 2015 |
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| المؤلفون: | Muneretto, Claudio, Alfieri, Ottavio, Cesana, Bruno Mario, Bisleri, Gianluigi, De Bonis, Michele, Di Bacco, Lorenzo, Rambaldini, Manfredo, Maureira, Juan Pablo, Laborde, Francois, Tespili, Maurizio, Repossini, Alberto, Folliguet, Thierry, DI BARTOLOMEO, ROBERTO, SAVINI, CARLO, FOLESANI, GIANLUCA |
| المساهمون: | Muneretto, Claudio, Alfieri, Ottavio, Cesana, Bruno Mario, Bisleri, Gianluigi, De Bonis, Michele, Di Bartolomeo, Roberto, Savini, Carlo, Folesani, Gianluca, Di Bacco, Lorenzo, Rambaldini, Manfredo, Maureira, Juan Pablo, Laborde, Francoi, Tespili, Maurizio, Repossini, Alberto, Folliguet, Thierry |
| سنة النشر: | 2015 |
| المجموعة: | IRIS Università degli Studi di Bologna (CRIS - Current Research Information System) |
| مصطلحات موضوعية: | aortic valve replacement, sutureless bioprosthesi, transcatheter valve implantation, Aged, 80 and over, Aortic Valve Stenosi, Female, Human, Male, Postoperative Complication, Propensity Score, Prosthesis Design, Retrospective Studie, Risk Assessment, Risk Factor, Survival Rate, Treatment Outcome, Heart Valve Prosthesi, Transcatheter Aortic Valve Replacement, Cardiology and Cardiovascular Medicine, Surgery, Pulmonary and Respiratory Medicine, Medicine (all) |
| الوصف: | Objective We sought to investigate the clinical outcomes of patients with isolated severe aortic stenosis and an intermediate- to high-risk profile treated by means of conventional surgery (surgical aortic valve replacement), sutureless valve implantation, or transcatheter aortic valve replacement in a multicenter evaluation. Methods Among 991 consecutive patients with isolated severe aortic stenosis and an intermediate- to high-risk profile (Society of Thoracic Surgeons score >4 and logistic European System for Cardiac Operative Risk Evaluation I >10), a propensity score analysis was performed on the basis of the therapeutic strategy: surgical aortic valve replacement (n = 204), sutureless valve implantation (n = 204), and transcatheter aortic valve replacement (n = 204). Primary end points were 30-day mortality and overall survival at 24-month follow-up; the secondary end point was survival free from a composite end point of major adverse cardiac events (defined as cardiac-related mortality, myocardial infarction, cerebrovascular accidents, and major hemorrhagic events) and periprosthetic regurgitation greater than 2. Results Thirty-day mortality was significantly higher in the transcatheter aortic valve replacement group (surgical aortic valve replacement = 3.4% vs sutureless = 5.8% vs transcatheter aortic valve replacement = 9.8%; P =.005). The incidence of postprocedural was 3.9% in asurgical aortic valve replacement vs 9.8% in sutureless vs 14.7% in transcatheter aortic valve replacement (P<.001) and peripheral vascular complications occurred in 0% of surgicalaortic valve replacement vs 0% of sutureless vs 9.8% transcatheter aortic valve replacement (P<.001). At 24-month follow-up, overall survival (surgical aortic valve replacement = 91.3% ± 2.4% vs sutureless = 94.9% ± 2.1% vs transcatheter aortic valve replacement = 79.5% ± 4.3%; P <.001) and survival free from the composite end point of major adverse cardiovascular events and periprosthetic regurgitation were significantly better in ... |
| نوع الوثيقة: | article in journal/newspaper |
| وصف الملف: | STAMPA |
| اللغة: | English |
| العلاقة: | info:eu-repo/semantics/altIdentifier/pmid/26384753; info:eu-repo/semantics/altIdentifier/wos/WOS:000365040700056; volume:150; issue:6; firstpage:1570; lastpage:1579; numberofpages:10; journal:JOURNAL OF THORACIC AND CARDIOVASCULAR SURGERY; http://hdl.handle.net/11585/545616Test; info:eu-repo/semantics/altIdentifier/scopus/2-s2.0-84947939351; http://www.elsevier.com/inca/publications/store/6/2/3/1/5/1/index.httTest |
| DOI: | 10.1016/j.jtcvs.2015.08.052 |
| الإتاحة: | https://doi.org/10.1016/j.jtcvs.2015.08.052Test http://hdl.handle.net/11585/545616Test http://www.elsevier.com/inca/publications/store/6/2/3/1/5/1/index.httTest |
| رقم الانضمام: | edsbas.DB61832B |
| قاعدة البيانات: | BASE |
| DOI: | 10.1016/j.jtcvs.2015.08.052 |
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