التفاصيل البيبلوغرافية
| العنوان: |
Study on Quality Standard of Tibetan Medicine Corydalis dasyptera Maxim. |
| المؤلفون: |
Yi SHI1, Yunfeng HAN1, Xi TANG1, Jie GAO1, Lin PAN1, Yi ZHANG1, Xianrong LAI1 vegf@qq.com, Duojie LONGZHU2 850002632@qq.com |
| المصدر: |
Medicinal Plant. Oct2021, Vol. 12 Issue 5, p28-32. 5p. |
| مصطلحات موضوعية: |
*TIBETAN medicine, *QUALITY standards, *CORYDALIS, *HIGH performance liquid chromatography, *QUALITY control |
| مستخلص: |
[Objectives] To establish the quality standard of Tibetan medicine Corydalis dasyptera Maxim. [Methods] According to the research method of drug quality standard in the appendix of 2020 edition of Chinese Pharmacopoeia, 8 batches of C. dasyptera Maxim. from different habitats were studied by character identification, microscopic identification and TLC identification. The content of water, total ash, acid-insoluble ash and alcohol-soluble extract was determined, and the content of protopine in medicinal materials was determined by high performance liquid chromatography(HPLC). [Results] The properties and microscopic characteristics of C. dasyptera Maxim. were determined. The TLC characteristic spots of the medicinal materials were clear, the degree of separation was good, and the specificity was strong. Both the test sample and the control sample showed the same yellow-green spots in the corresponding position. It was tentatively determined that the water content of C. dasyptera Maxim. should not exceed 14.0%, the total ash content should not exceed 14.0%, the acid-insoluble ash content should not exceed 3.0%, and the alcohol-soluble extract content should not be less than 18.0%. There was a good linear relationship between the concentration of protopine and the peak area in the range of 16.64-166.40 μg ·10~(-3)(r=0.999 6). The average recovery rate was 98.47% and the RSD was 1.21%(n=6). The content of protopine in 8 batches of C. dasyptera Maxim. was 0.023%-0.093%. [Conclusions] The established quality research method is simple, stable and reliable, and can be used for the quality control of C. dasyptera Maxim. [ABSTRACT FROM AUTHOR] |
| قاعدة البيانات: |
Academic Search Index |
