A PROSPECTIVE STUDY OF COMPARISON OF EPIDURAL BUPIVACAINE, FENTANYLAND THEIR COMBINATION FOR POSTOPERATIVE ANALGESIA IN LOWER ABDOMINALAND LOWER EXTREMITY SURGERY
التفاصيل البيبلوغرافية
العنوان:
A PROSPECTIVE STUDY OF COMPARISON OF EPIDURAL BUPIVACAINE, FENTANYLAND THEIR COMBINATION FOR POSTOPERATIVE ANALGESIA IN LOWER ABDOMINALAND LOWER EXTREMITY SURGERY
BACKGROUND Epidural analgesia with local anaesthetics and opioids provide good control of postoperative pain in lower abdominal and lower extremity surgery. AIM To evaluate and compare the analgesic action and adverse effects of epidural bupivacaine, fentanyl and their combination in postoperative period. METHODS 75 patients undergoing elective infraumbilical surgery were allocated in three groups in a randomized double blinded fashion. Postoperative analgesia was maintained with continuous infusion of epidural drug in the following manner: Group B: Injection Bupivacaine 0.125% @ 0.1mL/kg/hr through epidural route; Group F: Injection Fentanyl 4µg/mL @ 0.1mL/kg/hr through epidural route; Group BF: Injection Bupivacaine 0.0625% and Fentanyl 2µ/mL @ 0.1mL/kg/hr through epidural route. RESULTS VAS score were almost similar in all three groups at 00, 04, 08hrs and not clinically significant at that point of time. VAS score showed significant difference at 12, 20 and 24 hrs, being persistently lower in Gr BF than Gr B and Gr F. According to VRS Scale Score at 04 hrs majority of patients of all three groups had mild-to-moderate pain (p=0.278). At 08 hrs, 24% (p=0.082), 12 hrs 60% (
