Pharmacological Effects of Ba-Wei-Xi-Lei Powder on Ulcerative Colitis in Rats with Enema Application
| العنوان: | Pharmacological Effects of Ba-Wei-Xi-Lei Powder on Ulcerative Colitis in Rats with Enema Application |
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| المؤلفون: | Hai-Mei Zhao, Duan-Yong Liu, Zeng-Ping Xin, Aiping Lu, Ning Zhao |
| المصدر: | The American Journal of Chinese Medicine. 34:461-469 |
| بيانات النشر: | World Scientific Pub Co Pte Ltd, 2006. |
| سنة النشر: | 2006 |
| مصطلحات موضوعية: | CD4-Positive T-Lymphocytes, medicine.medical_specialty, Herbal Medicine, medicine.medical_treatment, Lymphocyte, Enema, CD8-Positive T-Lymphocytes, Gastroenterology, Sulfasalazine, Internal medicine, medicine, Animals, Colitis, business.industry, General Medicine, T lymphocyte, medicine.disease, Immunohistochemistry, Ulcerative colitis, digestive system diseases, Rats, medicine.anatomical_structure, Complementary and alternative medicine, Colitis, Ulcerative, Tumor necrosis factor alpha, Rabbits, Powders, business, Adjuvant, Drugs, Chinese Herbal, medicine.drug |
| الوصف: | Ba-Wei-Xi-Lei powder is a classical herbal mixture, and is widely used for the treatment of oral ulcer and ulcerative colitis. This study aimed to explore the effect of Ba-Wei-Xi-Lei powder with enema application on ulcerative colitis in rats. Ulcerative colitis was induced by immunization with rabbit's colonic mucosal protein emulsified with Completely Freund's Adjuvant. The mucosal inflammatory reaction and ulcer have been observed in the model rats. Characteristic changes of ulceractive colitis include that CD4 lymphocyte increased in peripheral blood while CD8 lymphocyte decreased; CD8 lymphocyte and TNF-α expression area increased in colonic mucosa, while CD4 lymphocyte decreased. Ba-Wei-Xi-Lei powder and sulfasalazine with enema application could alleviate the pathological changes in the model rats. The results suggest that the pharmacological effects of Ba-Wei-Xi-Lei powder on ulcerative colitis in rats are similar to the effect of sulfasalazine. |
| تدمد: | 1793-6853 0192-415X |
| الوصول الحر: | https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7e45931866cd594063eb91f5e992683bTest https://doi.org/10.1142/s0192415x06003990Test |
| رقم الانضمام: | edsair.doi.dedup.....7e45931866cd594063eb91f5e992683b |
| قاعدة البيانات: | OpenAIRE |
| تدمد: | 17936853 0192415X |
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