دورية أكاديمية
Development of a deformable dosimetric phantom to verify dose accumulation algorithms for adaptive radiotherapy
| العنوان: | Development of a deformable dosimetric phantom to verify dose accumulation algorithms for adaptive radiotherapy |
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| المؤلفون: | Hualiang Zhong, Jeffrey Adams, Carri Glide-Hurst, Hualin Zhang, Haisen Li, Indrin J Chetty |
| المصدر: | Journal of Medical Physics, Vol 41, Iss 2, Pp 106-114 (2016) |
| بيانات النشر: | Wolters Kluwer Medknow Publications, 2016. |
| سنة النشر: | 2016 |
| المجموعة: | LCC:Medical physics. Medical radiology. Nuclear medicine |
| مصطلحات موضوعية: | Adaptive radiation therapy, dose accumulation, quality assurance, Medical physics. Medical radiology. Nuclear medicine, R895-920 |
| الوصف: | Adaptive radiotherapy may improve treatment outcomes for lung cancer patients. Because of the lack of an effective tool for quality assurance, this therapeutic modality is not yet accepted in clinic. The purpose of this study is to develop a deformable physical phantom for validation of dose accumulation algorithms in regions with heterogeneous mass. A three-dimensional (3D) deformable phantom was developed containing a tissue-equivalent tumor and heterogeneous sponge inserts. Thermoluminescent dosimeters (TLDs) were placed at multiple locations in the phantom each time before dose measurement. Doses were measured with the phantom in both the static and deformed cases. The deformation of the phantom was actuated by a motor driven piston. 4D computed tomography images were acquired to calculate 3D doses at each phase using Pinnacle and EGSnrc/DOSXYZnrc. These images were registered using two registration software packages: VelocityAI and Elastix. With the resultant displacement vector fields (DVFs), the calculated 3D doses were accumulated using a mass-and energy congruent mapping method and compared to those measured by the TLDs at four typical locations. In the static case, TLD measurements agreed with all the algorithms by 1.8% at the center of the tumor volume and by 4.0% in the penumbra. In the deformable case, the phantom's deformation was reproduced within 1.1 mm. For the 3D dose calculated by Pinnacle, the total dose accumulated with the Elastix DVF agreed well to the TLD measurements with their differences |
| نوع الوثيقة: | article |
| وصف الملف: | electronic resource |
| اللغة: | English |
| تدمد: | 0971-6203 1998-3913 |
| العلاقة: | http://www.jmp.org.in/article.asp?issn=0971-6203;year=2016;volume=41;issue=2;spage=106;epage=114;aulast=ZhongTest; https://doaj.org/toc/0971-6203Test; https://doaj.org/toc/1998-3913Test |
| DOI: | 10.4103/0971-6203.181641 |
| الوصول الحر: | https://doaj.org/article/8512138b3eb949a8b36caae71b1739baTest |
| رقم الانضمام: | edsdoj.8512138b3eb949a8b36caae71b1739ba |
| قاعدة البيانات: | Directory of Open Access Journals |
Full Text Finder | تدمد: | 09716203 19983913 |
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| DOI: | 10.4103/0971-6203.181641 |