دورية أكاديمية
The Incidence of Chiari Malformations in Patients with Isolated Sagittal Synostosis
| العنوان: | The Incidence of Chiari Malformations in Patients with Isolated Sagittal Synostosis |
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| المؤلفون: | Amani Ali Davis, Giulio Zuccoli, Mostafa M. Haredy, Lauren Runkel, Joseph Losee, Ian F. Pollack, Mandeep S. Tamber, Elizabeth Tyler-Kabara, Jesse A. Goldstein, Ken-K Nischal |
| المصدر: | Plastic and Reconstructive Surgery, Global Open, Vol 7, Iss 2, p e2090 (2019) |
| بيانات النشر: | Wolters Kluwer |
| سنة النشر: | 2019 |
| المجموعة: | Directory of Open Access Journals: DOAJ Articles |
| مصطلحات موضوعية: | Surgery, RD1-811 |
| الوصف: | Background:. We report the incidence of Chiari malformation I (CMI) in a cohort of 377 patients with isolated sagittal synostosis (ISS), which is to the best of our knowledge the largest such series reported to date. Methods:. A retrospective review of patients seen at a single institution from 2007 to 2017 was completed. ISS, Chiari malformations (CMI and CMII) and hydrocephalus were diagnosed by a senior neuroradiologist (G.Z.). Patients who met the inclusion criteria were divided into early (group A) and late (group B) presenting groups, as well as operated (group I) and unoperated (group II) groups. The patients were further subdivided into group AI (early operated), group AII (early unoperated), group BI (late operated), and group BII (late unoperated). Once identified, patient notes were examined for the following data sets: date of birth, age of presentation, age at last follow-up, other systemic conditions as well as molecular testing results. Surgical interventions, ophthalmological, and other relevant data were recorded. Statistical analysis was run in the form of a chi-square test to identify a significant difference between each subgroup. A literature review of the incidence of Chiari malformations in patients with ISS was conducted. Results:. Three hundred seventy-seven patients constitute the study’s total cohort (272 were males and 105 females). This cohort was divided into patients who underwent surgical repair of ISS (group 1: n = 200), and patients who did not (group 2: n = 177). The entire cohort was also divided into early (group A: n = 161) and late (group B: n = 216) presenting craniosynostosis. In the total cohort, 22/377 (5.8%) patients with CMI were identified. CMI was found in 14/200 (7.0%) patients in group I, and 8/177 (4.5%) patients in group II. CMI was found in 2/161 (1%) patients in group A, and 20/216 (9.2%) patients in group B. The incidence of CMI in group AI (early operated) was 2/151 (1.3%), in group AII (early unoperated) was 0/10, in group BI (late operated) was 11/49 ... |
| نوع الوثيقة: | article in journal/newspaper |
| اللغة: | English |
| تدمد: | 2169-7574 |
| العلاقة: | http://journals.lww.com/prsgo/fulltext/10.1097/GOX.0000000000002090Test; https://doaj.org/toc/2169-7574Test; https://doaj.org/article/940384ff8af440e39ae0e5f5e7592fe1Test |
| DOI: | 10.1097/GOX.0000000000002090 |
| الإتاحة: | https://doi.org/10.1097/GOX.0000000000002090Test https://doaj.org/article/940384ff8af440e39ae0e5f5e7592fe1Test |
| رقم الانضمام: | edsbas.A909EF3D |
| قاعدة البيانات: | BASE |
Full Text Finder | تدمد: | 21697574 |
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| DOI: | 10.1097/GOX.0000000000002090 |