Comparison of cell salvage with one and two suction devices during cesarean section in patients with placenta previa and/or accrete: a randomized controlled trial
| العنوان: | Comparison of cell salvage with one and two suction devices during cesarean section in patients with placenta previa and/or accrete: a randomized controlled trial |
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| المؤلفون: | Hong Chen, Hua Tan, Pei-Xin Luo, Yi-Fang Shen, Chang-Cheng Lyu, Xiao-Wei Qian, Xin-Zhong Chen, Pei-Fang Wei |
| المصدر: | Chinese Medical Journal, Iss 6, Pp 638-643 (2020) Chinese Medical Journal |
| بيانات النشر: | Wolters Kluwer, 2020. |
| سنة النشر: | 2020 |
| مصطلحات موضوعية: | Suction (medicine), Adult, medicine.medical_specialty, Amniotic fluid, Erythrocytes, Placenta Previa, lcsh:Medicine, Suction, law.invention, 03 medical and health sciences, 0302 clinical medicine, Randomized controlled trial, law, Pregnancy, Placenta, Medicine, Humans, In patient, Placenta accrete, business.industry, Cesarean Section, Significant difference, Blood transfusion, lcsh:R, General Medicine, Original Articles, medicine.disease, Amniotic Fluid, Surgery, Placenta previa, medicine.anatomical_structure, 030220 oncology & carcinogenesis, Cell salvage, Mann–Whitney U test, Female, business, 030217 neurology & neurosurgery |
| الوصف: | Background. Cell salvage has recently been recommended for obstetric use in cases with a high risk of massive hemorrhage during cesarean section (CS). However, limited data are available to support the use of one suction device to collect lost blood. This study aimed to investigate the volume of red blood cells (RBCs) salvaged and the components of amniotic fluid (AF) in blood salvaged by one suction device or two devices during CS in patients with placenta previa and/or accrete. Methods. Thirty patients with placenta previa and/or accrete undergoing elective CS in the Women's Hospital of Zhejiang University School of Medicine were recruited for the present study from November 1, 2017 to December 1, 2018. The patients were randomly assigned to one of the two groups according to an Excel-generated random number sheet: Group 1 (n = 15), in which only one suction device was used to aspirate all blood and AF, and Group 2 (n = 15), in which a second suction device was mainly used to aspirate AF before the delivery of the placenta. Three samples of blood per patient (pre-wash, post-wash, and post-filtration) were collected to measure AF components. The salvaged RBC volumes were recorded. Continuous data of pre-wash, post-wash, and post-filtration samples were analyzed by using one-way analysis of variance with Tukey's test for multiple comparisons, or Kruskal-Wallis test with Dunn test for multiple comparisons. Comparisons of continuous data between Group 1 and Group 2 were conducted using Student's t test or Mann-Whitney U test. Results. The salvaged RBC volume was significantly higher in Group 1 than that in Group 2 (401.6 ± 77.2 mL vs. 330.1 ± 53.3 mL, t = 4.175, P 0.05). The mean percentage of fetal RBCs post-filtration was (1.8 ± 0.8)% with a range of 1.0% to 3.5% and (1.9 ± 0.9)% with a range of 0.7% to 4.0% in Groups 1 and 2, respectively, showing no significant difference between the two groups (U = 188.5, P = 0.651). Conclusion. Cell salvage performed by one suction device could result in higher volume of salvaged RBCs and can be used safely for CS in patients with placenta previa and/or accrete when massive hemorrhage occurs. Trial registration number. ChiCTR-INR-17012926, http://www.chictr.org.cnTest/ Chinese Clinical Trial Registry. |
| اللغة: | English |
| تدمد: | 2542-5641 0366-6999 |
| الوصول الحر: | https://explore.openaire.eu/search/publication?articleId=doi_dedup___::893fbc3c2e2db0675ab4b246c86288e0Test http://journals.lww.com/10.1097/CM9.0000000000000699Test |
| حقوق: | OPEN |
| رقم الانضمام: | edsair.doi.dedup.....893fbc3c2e2db0675ab4b246c86288e0 |
| قاعدة البيانات: | OpenAIRE |
| تدمد: | 25425641 03666999 |
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