التفاصيل البيبلوغرافية
| العنوان: |
Preoperative magnetic resonance imaging predicts clinicopathological parameters and stages of endometrial carcinomas. |
| المؤلفون: |
Chia-Ying Wu, Yi-Jou Tai, I-Lun Shih, Ying-Cheng Chiang, Yu-Li Chen, Heng-Cheng Hsu, Wen-Fang Cheng |
| المصدر: |
Cancer Medicine; Feb2022, Vol. 11 Issue 4, p993-1004, 12p |
| مصطلحات موضوعية: |
MAGNETIC resonance imaging, ENDOMETRIAL cancer, CLINICAL pathology, INTRA-aortic balloon counterpulsation, ENDOMETRIAL surgery, TUMOR classification |
| مستخلص: |
Background: We investigated the agreement and accuracy of preoperative magnetic resonance imaging (MRI) with postoperative pathological characteristics and stages of endometrial endometrioid carcinoma (EEC). Methods: We recruited 527 women with EEC who underwent staging surgery at a single medical institution. The preoperative MRI, stages, and clinical and pathological parameters, including myometrial invasion (MI), cervical invasion (CI), adnexal metastasis (AM), intra-abdominal metastasis, and pelvic and/or para-aortic nodal metastasis, were recorded and analyzed. The agreement and accuracy between the preoperative MRI findings and these parameters and stages were assessed. Results: The rate of the preoperative MRI-based clinical stage matching the postoperative surgical stage was 85.2% in International Federation of Gynecology and Obstetrics stage IA, 51.9% in stage IB, 35.5% in stage II, 5.3% in stage IIIA, 33.3% in stage IIIB, 28.6% in stage IIIC1, 64.3% in stage IIIC2, and 93.8% in stage IVB. The consistency between radiologists and pathologists was 80.5% for deep MI, 91.5% for cervical invasion, 92.2% for adnexal metastasis, 98.9% for intra-abdominal metastasis, and 87.5% and 92.2% for pelvic and para-aortic nodal metastases, respectively. The negative predictive value of intra-abdominal metastasis was the highest with 99.8%. Conclusions: Preoperative MRI could be an excellent tool for routine preoperative assessment to predict pathological parameters and stages of EEC, especially in excluding intra-abdominal metastatic disease. [ABSTRACT FROM AUTHOR] |
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| قاعدة البيانات: |
Complementary Index |
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