دورية أكاديمية

Experiences with intestinal failure from an intestinal rehabilitation unit in a country without home parenteral nutrition.

التفاصيل البيبلوغرافية
العنوان: Experiences with intestinal failure from an intestinal rehabilitation unit in a country without home parenteral nutrition.
المؤلفون: Nikoupour, Hamed, Arasteh, Peyman, Shamsaeefar, Alireza, Ghanbari, Fardin, Boorboor, Arash, Almayali, Ali Mosa Jafar, Shafiekhani, Mojtaba, Samidoust, Pirouz, Shahriarirad, Reza, Shojazadeh, Alireza, Ranjbar, Keivan, Darabi, Mohammad Hasan, Tangestanipour, Sina, Hosseini, Seyed Morteza, Zahiri, Leila, Nikeghbalian, Saman
المصدر: JPEN Journal of Parenteral & Enteral Nutrition; May2022, Vol. 46 Issue 4, p946-957, 12p
مصطلحات موضوعية: INTESTINAL diseases, PARENTERAL feeding, TRANSPLANTATION of organs, tissues, etc., SHORT bowel syndrome, FISTULA
مستخلص: Objective: For the first time, we reported experiences with an intestinal rehabilitation unit (IRU) from a country without home parenteral nutrition (HPN). Methods: We included patients with a diagnosis of intestinal failure (IF) since the establishment of our IRU from February 2018 to February 2020. We further report on our protocols for management of enterocutaneous fistulas (ECFs), short‐bowel syndrome (SBS), chronic intestinal pseudo‐obstruction and motility disorders. Results: Among a total of 349 patients who have been admitted, 100 patients had IF and were included. Mean (SD) age of patients was 46.3 ± 16.1 years. Most common cause of IF was ECFs (32%), SBS (24%), and SBS + fistula (22%). Most common causes of SBS were mesenteric ischemia (63.3%) and repeated surgery (22.4%). Median (interquartile range [IQR]) duration of parenteral nutrition (PN) for patients was 32 (18–60) days. The most common reconstructive surgery performed was resection and anastomosis (75.4%), followed by serial transverse enteroplasty procedure (10.5%) and closure of ostoma (7%). Patients were hospitalized for a median (IQR) of 33 (17.5–61) days. Most common complications were sepsis (45%), catheter infections (43%), and catheter thrombosis (20%), respectively. At the final follow‐up, 61% stopped receiving PN, 23% became candidates for transplantation, and 16% died. Conclusion: Considering that most countries lack facilities for HPN, by establishing IRUs using specific treatment protocols and autologous gastrointestinal reconstruction techniques will provide a means to manage patients with IF, thus decreasing death rates and number of patients who require intestinal transplantations due to IF. [ABSTRACT FROM AUTHOR]
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قاعدة البيانات: Complementary Index
الوصف
تدمد:01486071
DOI:10.1002/jpen.2231