يعرض 1 - 8 نتائج من 8 نتيجة بحث عن '"Pithavala, Yazdi K."', وقت الاستعلام: 0.69s تنقيح النتائج
  1. 1
    دورية أكاديمية
    Evaluation of Lorlatinib Cerebrospinal Fluid Concentrations in Relation to Target Concentrations for Anaplastic Lymphoma Kinase (ALK) Inhibition.

    المؤلفون: Sun, Steven1,2, Pithavala, Yazdi K.2, Martini, Jean‐François3, Chen, Joseph2 Joseph.Chen@Pfizer.com

    المصدر: Journal of Clinical Pharmacology. Sep2022, Vol. 62 Issue 9, p1170-1176. 7p.

    مصطلحات موضوعية: *RESEARCH, *STATISTICS, *GENETIC mutation, *PROTEIN kinase inhibitors, *ANTINEOPLASTIC agents, *ANAPLASTIC lymphoma kinase, *CANCER patients, *CEREBROSPINAL fluid, *DATA analysis, *PHARMACODYNAMICS


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  2. 2
    دورية أكاديمية
    A literature review of liver function test elevations in rifampin drug–drug interaction studies.

    المؤلفون: Ibrahim, Sherry M.1 (AUTHOR), Pithavala, Yazdi K.2 (AUTHOR), Vourvahis, Manoli3 (AUTHOR), Chen, Joseph4 (AUTHOR) joseph.chen@pfizer.com

    المصدر: CTS: Clinical & Translational Science. Jul2022, Vol. 15 Issue 7, p1561-1580. 20p.

    مصطلحات موضوعية: *RITONAVIR, *RIFAMPIN, *LIVER function tests, *DRUG interactions, *LITERATURE reviews, *BIOTRANSFORMATION (Metabolism)

    النص الكامل

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  3. 3
    دورية أكاديمية
    Phase 1 Study Evaluating the Effects of the Proton Pump Inhibitor Rabeprazole and Food on the Pharmacokinetics of Lorlatinib in Healthy Participants.

    المؤلفون: Xu, Huiping, O'Gorman, Melissa T., Nepal, Sunil, James, Lee P., Ginman, Katherine, Pithavala, Yazdi K.

    المصدر: Clinical Pharmacology in Drug Development; Nov2021, Vol. 10 Issue 11, p1395-1404, 10p

    مصطلحات موضوعية: BIOAVAILABILITY, PROTON pump inhibitors, PHARMACOKINETICS, NON-small-cell lung carcinoma, ADVERSE health care events, MEALS, GASTRIC acid


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  4. 4
    دورية أكاديمية
    Population pharmacokinetic model with time‐varying clearance for lorlatinib using pooled data from patients with non‐small cell lung cancer and healthy participants.

    المؤلفون: Chen, Joseph, Houk, Brett, Pithavala, Yazdi K., Ruiz‐Garcia, Ana

    المصدر: CPT: Pharmacometrics & Systems Pharmacology; Feb2021, Vol. 10 Issue 2, p148-160, 13p

    مصطلحات موضوعية: NON-small-cell lung carcinoma, ANAPLASTIC lymphoma kinase, PROGNOSIS, PHARMACOKINETICS, PROTEIN-tyrosine kinases

    النص الكامل

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  5. 5
    دورية أكاديمية
    Metabolism, Excretion, and Pharmacokinetics of Lorlatinib (PF‐06463922) and Evaluation of the Impact of Radiolabel Position and Other Factors on Comparability of Data Across 2 ADME Studies.

    المؤلفون: Stypinski, Daria, Fostvedt, Luke, Lam, Justine L., Vaz, Alfin, Johnson, Theodore R., Boerma, Jan S., Pithavala, Yazdi K.

    المصدر: Journal of Clinical Pharmacology; Sep2020, Vol. 60 Issue 9, p1254-1267, 14p

    مصطلحات موضوعية: ANTINEOPLASTIC agents, COMPARATIVE studies, MOLECULAR structure, RADIOIMMUNOIMAGING, PHARMACODYNAMICS


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  6. 6
    دورية أكاديمية
    Treatment of advanced thyroid cancer with axitinib: Phase 2 study with pharmacokinetic/pharmacodynamic and quality-of-life assessments.

    المؤلفون: Locati, Laura D., Licitra, Lisa, Agate, Laura, Ou, Sai‐Hong I., Boucher, Andree, Jarzab, Barbara, Qin, Shukui, Kane, Madeleine A., Wirth, Lori J., Chen, Connie, Kim, Sinil, Ingrosso, Antonella, Pithavala, Yazdi K., Bycott, Paul, Cohen, Ezra E. W.

    المصدر: Cancer (0008543X); Sep2014, Vol. 120 Issue 17, p2694-2703, 10p

    مصطلحات موضوعية: THYROID cancer treatment, PHARMACOKINETICS, PHARMACODYNAMICS, IODINE isotopes, PROTEIN-tyrosine kinase inhibitors, HEALTH outcome assessment, QUALITY of life

    النص الكامل

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  7. 7
    دورية أكاديمية
    Population pharmacokinetic analysis of axitinib in healthy volunteers.

    المؤلفون: Garrett, May, Poland, Bill, Brennan, Meghan, Hee, Brian, Pithavala, Yazdi K., Amantea, Michael A.

    المصدر: British Journal of Clinical Pharmacology; Mar2014, Vol. 77 Issue 3, p480-492, 13p, 3 Charts, 4 Graphs

    مصطلحات موضوعية: PHARMACOKINETICS, VASCULAR endothelial growth factors, RENAL cell carcinoma, BODY weight, BIOAVAILABILITY

    النص الكامل

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  8. 8
    دورية أكاديمية
    Axitinib in Metastatic Renal Cell Carcinoma: Results of a Pharmacokinetic and Pharmacodynamic Analysis.

    المؤلفون: Rini, Brian I., Garrett, May, Poland, Bill, Dutcher, Janice P., Rixe, Olivier, Wilding, George, Stadler, Walter M., Pithavala, Yazdi K., Kim, Sinil, Tarazi, Jamal, Motzer, Robert J.

    المصدر: Journal of Clinical Pharmacology; May2013, Vol. 53 Issue 5, p491-504, 14p

    مصطلحات موضوعية: CONFIDENCE intervals, EPIDEMIOLOGY, GOODNESS-of-fit tests, METASTASIS, PROTEIN kinases, RENAL cell carcinoma, DATA analysis, PROPORTIONAL hazards models, RETROSPECTIVE studies, RECEIVER operating characteristic curves, DATA analysis software, DESCRIPTIVE statistics


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