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المؤلفون: Irene Bozzoni, Rino Ragno, Ubaldo Gioia, Pietro Laneve, Antonello Mai, Elisa Caffarelli
المساهمون: Department of Medicinal Chemistry and Technologies, Institut Pasteur, Fondation Cenci Bolognetti - Istituto Pasteur Italia, Fondazione Cenci Bolognetti, Réseau International des Instituts Pasteur (RIIP)-Réseau International des Instituts Pasteur (RIIP)-Università degli Studi di Roma 'La Sapienza' = Sapienza University [Rome], Department of Biology and Biotechnology 'Charles Darwin', Institute of Molecular Biology and Pathology, CNR, Università degli Studi di Roma 'La Sapienza' = Sapienza University [Rome], This work was supported by the European Union SIROCCO project (LSHG-CT-2006–07900), the European Science Foundation NuRNASu project , the Associazione Italiana per la Ricerca sul Cancro, the Italian Progetti di Ricerca di Interesse Nazionale, the Centro di Eccellenza Biologia eMedicina Molecolare (Rome, Italy), and the Fondazione Roma(Italy). U.G. was supported by a fellowship from the Fondazione Italiana per la Ricerca sul Cancro., European Project: LSHG-CT-2006–07900, Réseau International des Instituts Pasteur (RIIP)-Réseau International des Instituts Pasteur (RIIP)-Università degli Studi di Roma 'La Sapienza' = Sapienza University [Rome] (UNIROMA), CNR Istituto di Biologia e Patologia Molecolari [Roma] (CNR | IBPM), National Research Council of Italy | Consiglio Nazionale delle Ricerche (CNR)
المصدر: ChemMedChem
ChemMedChem, Wiley-VCH Verlag, 2011, 6 (10), pp.1797-805. ⟨10.1002/cmdc.201100281⟩
ChemMedChem, 2011, 6 (10), pp.1797-805. ⟨10.1002/cmdc.201100281⟩
6 (2011): 1797–1805. doi:10.1002/cmdc.201100281
info:cnr-pdr/source/autori:Ragno R, Gioia U, Laneve P, Bozzoni I, Mai A, Caffarelli E./titolo:Identification of Small-Molecule Inhibitors of the XendoU Endoribonucleases Family/doi:10.1002%2Fcmdc.201100281/rivista:ChemMedChem (Print)/anno:2011/pagina_da:1797/pagina_a:1805/intervallo_pagine:1797–1805/volume:6
Chemmedchemمصطلحات موضوعية: rna processing, autodock, endoribonucleases, structure-based drug design, xendou family, MESH: Catalytic Domain, Pregnancy Proteins, Xenopus Proteins, medicine.disease_cause, 01 natural sciences, Biochemistry, Xenopus laevis, chemistry.chemical_compound, Endoribonucleases, Catalytic Domain, Drug Discovery, MESH: Animals, Enzyme Inhibitors, General Pharmacology, Toxicology and Pharmaceutics, MESH: Xenopus Proteins, Coronavirus, chemistry.chemical_classification, 0303 health sciences, MESH: Pregnancy Proteins, Full Paper, biology, Full Papers, Small molecule, 3. Good health, Cell biology, MESH: Enzyme Inhibitors, Molecular Medicine, structure‐based drug design, MESH: Endoribonucleases, MESH: Enzyme Activation, Small Molecule Libraries, 03 medical and health sciences, Biosynthesis, MESH: Computer Simulation, MESH: Small Molecule Libraries, MESH: Xenopus laevis, medicine, Animals, Humans, Computer Simulation, [SDV.BBM]Life Sciences [q-bio]/Biochemistry, Molecular Biology, 030304 developmental biology, Pharmacology, Virtual screening, Binding Sites, MESH: Humans, Organic Chemistry, Active site, Molecular biology, 0104 chemical sciences, Enzyme Activation, 010404 medicinal & biomolecular chemistry, Enzyme, chemistry, MESH: Binding Sites, Docking (molecular), biology.protein
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9e661b3a8e0aedde65af355aa69925b8Test
http://hdl.handle.net/11573/418879Test -
2دورية أكاديمية
المؤلفون: Du Pasquier, D., Chesneau, A., Ymlahi-Ouazzani, Q., Boistel, R., Pollet, N., Ballagny, C., Sachs, L. M., Demeneix, B., Mazabraud, A.
المساهمون: Evolution des régulations endocriniennes (ERE), Muséum national d'Histoire naturelle (MNHN)-Centre National de la Recherche Scientifique (CNRS), Centre de génétique moléculaire (CGM), Centre National de la Recherche Scientifique (CNRS), Développement et évolution (DE), Université Paris-Sud - Paris 11 (UP11)-Centre National de la Recherche Scientifique (CNRS)
المصدر: ISSN: 1526-954X.
مصطلحات موضوعية: MESH: Amino Acid Sequence, MESH: Animals, MESH: Molecular Sequence Data, MESH: Sequence Homology, Amino Acid, MESH: Xenopus laevis, Genetically Modified, MESH: Apoptosis, MESH: BH3 Interacting Domain Death Agonist Protein, MESH: Cell Lineage, MESH: Lens, Crystalline, MESH: Mitochondria, [SDV.BBM]Life Sciences [q-bio]/Biochemistry, Molecular Biology
العلاقة: info:eu-repo/semantics/altIdentifier/pmid/17154276; hal-00179423; https://hal.science/hal-00179423Test; PUBMED: 17154276
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3دورية أكاديمية
المؤلفون: Nutt, S. L., Bronchain, Odile, Hartley, K. O., Amaya, E.
المساهمون: Développement et évolution (DE), Université Paris-Sud - Paris 11 (UP11)-Centre National de la Recherche Scientifique (CNRS)
المصدر: ISSN: 1526-954X.
مصطلحات موضوعية: MESH: Animals, Genetically Modified, MESH: Male, MESH: Morpholines, MESH: Oligonucleotides, Antisense, MESH: Promoter Regions, Genetic, MESH: Protein Biosynthesis, MESH: Xenopus, MESH: Xenopus laevis, MESH: Crystallins, MESH: Embryo, Nonmammalian, MESH: Female, MESH: Gene Expression Regulation, Developmental, MESH: Genes, Reporter, MESH: Green Fluorescent Proteins, MESH: Larva, MESH: Luminescent Proteins, [SDV.NEU]Life Sciences [q-bio]/Neurons and Cognition [q-bio.NC]
العلاقة: info:eu-repo/semantics/altIdentifier/pmid/11477685; hal-00741914; https://hal.science/hal-00741914Test; PUBMED: 11477685
الإتاحة: https://hal.science/hal-00741914Test
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4دورية أكاديمية
المؤلفون: Carlier, E., Avdonin, V., Geib, S., Fajloun, Z., Kharrat, R., Rochat, H., Sabatier, J.-M., Hoshi, T., de Waard, M.
المساهمون: Institut Jean Roche - Biologie des interactions cellulaires (IJRBIC), Université de la Méditerranée - Aix-Marseille 2-Université Paul Cézanne - Aix-Marseille 3-Assistance Publique - Hôpitaux de Marseille (APHM)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Centre National de la Recherche Scientifique (CNRS), University of Iowa Iowa City, Laboratoire des Venins et Toxines, Institut Pasteur de Tunis, Institut Pasteur de Tunis, Réseau International des Instituts Pasteur (RIIP)-Réseau International des Instituts Pasteur (RIIP), We thank Dr Jacques Neyton (Ecole Normale Supérieure) for critical comments on the manuscript.
المصدر: ISSN: 1397-002X.
مصطلحات موضوعية: expression, maurotoxin, scorpion toxin, Xenopus oocyte, voltage-gated K+ channel, ShakerB, MESH: Amino Acid Motifs, MESH: Amino Acid Sequence, MESH: Scorpion Venoms/pharmacology, MESH: Shaker Superfamily of Potassium Channels, MESH: Animals, MESH: Sodium Channels/metabolism, MESH: Xenopus laevis, MESH: CHO Cells, MESH: Cricetinae, MESH: Disulfides, MESH: Dose-Response Relationship, Drug, MESH: Gene Expression, MESH: Oocytes, MESH: Microinjections, MESH: Molecular Sequence Data, MESH: Patch-Clamp Techniques, MESH: Potassium Channel Blockers, MESH: Potassium Channels/metabolism, MESH: Protein Conformation, MESH: RNA, Complementary/metabolism, MESH: Scorpion Venoms/chemistry, MESH: Scorpion Venoms/metabolism
العلاقة: info:eu-repo/semantics/altIdentifier/pmid/10888198; pasteur-02045635; https://riip.hal.science/pasteur-02045635Test; PUBMED: 10888198
الإتاحة: https://doi.org/10.1034/j.1399-3011.2000.00715.xTest
https://riip.hal.science/pasteur-02045635Test
