المؤلفون: Simeon Schaub, Iris-Katharina Penner, Bettina Fischer-Barnicol, Jean-Marie Annoni, Özgür Yaldizli, Bettina Frey, Jana Pöttgen, Sara Bagutti, Dominik Zwahlen, Mireille Neuhaus, Marie‐ Dominique Martory, Jean-Marc Burgunder

مصطلحات موضوعية: Adult, Male, medicine.medical_specialty, Multiple Sclerosis, Anxiety, Neuropsychological Tests, 050105 experimental psychology, 03 medical and health sciences, 0302 clinical medicine, Cognition, Social cognition, Theory of mind, Medicine, Raw score, Humans, 0501 psychology and cognitive sciences, Effects of sleep deprivation on cognitive performance, Psychiatry, Social Behavior, 610 Medicine & health, Depression (differential diagnoses), Facial affect, business.industry, Depression, Multiple sclerosis, 05 social sciences, Middle Aged, medicine.disease, Neurology, Social Perception, Female, Neurology (clinical), medicine.symptom, business, 030217 neurology & neurosurgery, Clinical psychology

الوصف: Background Multiple sclerosis (MS) has been associated with deficits in social cognition. However, little is known about which domains of social cognition are predominantly affected and what other factors are associated with it. Objectives 1) To characterize social cognition deficit in a group of MS outpatients. 2) To relate impairment in social cognition to overall cognitive status, depression and fatigue. Methods Thirty-five MS patients (mean disease duration 12.9 years, median EDSS 3) and thirty-four healthy controls (HCs) were examined using the German version of the Geneva Social Cognition Scale to measure different domains of social cognition. Standard neuropsychological testing was applied to all patients and to 20 HCs. Patient-reported outcomes included questionnaires for fatigue, depression, anxiety and executive-behavioural disturbances. Results The mean social cognition raw score was lower in the MS patients compared to the HCs (86.5±8.7 vs. 91.2±5.9 p=0.005; d=0.6) and did not correlate with EDSS or disease duration. The difference was driven by facial affect recognition and the understanding of complex social situations (14% and 23% of patients under the cut-off, respectively). The impairment in these two tasks did not correlate with general cognitive performance or depression but with fatigue. Conclusions The impairment in our group was restricted to high order and affective social cognition tasks and independent of general cognitive performance, EDSS, disease duration and depression. Fatigue correlated with social cognition performance, which might be due to common underlying neuronal networks. This article is protected by copyright. All rights reserved.

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f51514869fd2dba4bdd97ab979c21dc7Test

المؤلفون: Chantal M. E. Tallaksen, P. De Jonghe, Christian Mariotti, Sarah J. Tabrizi, Ludger Schöls, Z. Szolnoki, B. Fontaine, Jonathan Baets, Massimo Zeviani, C Van Broeckhoven, T. Gasser, Antonella Spinazzola, Josef Finsterer, Timothy Lynch, S. Di Donato, Alexander Lossos, Jean-Marc Burgunder, Hanne F. Harbo

المصدر: European Handbook of Neurological Management
European handbook of neurological management, volume 2 / Gilhus, Nils Erik [edit.]

مصطلحات موضوعية: Dystonia, Parkinson's disease, Huntington's disease, business.industry, Medicine, Human medicine, business, medicine.disease, Neuroscience

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2701be50bfd70f8e2557df04c844fa69Test
https://doi.org/10.1002/9781444346268.ch4Test

المؤلفون: Dong Liang Ma, Yong Cheng Tang, Peng Min Chen, Shwn Chin Chia, Feng Li Jiang, Jean‐Marc Burgunder, Wei Ling Lee, Feng Ru Tang

المصدر: Journal of Neuroscience Research; Jan2006, Vol. 83 Issue 2, p318-331, 14p