المؤلفون: Qin, Wei^1,2 (AUTHOR), Shao, Ling^1,3 (AUTHOR), Wang, Jun² (AUTHOR), Zhang, Huan² (AUTHOR), Wang, Yao² (AUTHOR), Zhang, Xiaqing^2,4 (AUTHOR), Xie, Shaoyu² (AUTHOR), Pan, Fan² (AUTHOR), Cheng, Kai² (AUTHOR), Ma, Liguo² (AUTHOR), Chen, Yafei² (AUTHOR), Song, Jian¹ (AUTHOR), Gao, Dawei⁵ (AUTHOR), Chen, Zhichao⁵ (AUTHOR), Yang, Wei⁵ (AUTHOR), Zhu, Rui⁵ (AUTHOR), Su, Hong¹ (AUTHOR) suhong5151@sina.com

المصدر: Journal of Viral Hepatitis. Mar2024, Vol. 31 Issue 3, p143-150. 8p.

مصطلحات موضوعية: *PREMATURE labor, *LOW birth weight, *HEPATITIS B vaccines, *CHILDBIRTH, *PREMATURE infants, *BOOSTER vaccines

مستخلص: Previous studies did not provide substantial evidence for long‐term immune persistence after the hepatitis B vaccine (HepB) in preterm birth (PTB) children. Consequently, there is ongoing controversy surrounding the booster immunization strategy for these children. Therefore, we conducted a retrospective cohort study to evaluate the disparities in immune persistence between PTB children and full‐term children. A total of 1027 participants were enrolled in this study, including 505 PTB children in the exposure group and 522 full‐term children in the control group. The negative rate of hepatitis B surface antibody (HBsAb) in the PTB group was significantly lower than that in the control group (47.9% vs. 41.4%, p =.035). The risk of HBsAb‐negative in the exposure group was 1.5 times higher than that in the control group (adjusted odds ratio [aOR] = 1.5, 95% confidence interval [CI]: 1.1–2.0). The geometric mean concentration (GMC) of HBsAb was much lower for participants in the exposure group compared to participants in the control group (9.3 vs. 12.4 mIU/mL, p =.029). Subgroup analysis showed that the very preterm infants (gestational age <32 weeks) and the preterm low birth weight infants (birth weight <2000 g) had relatively low GMC levels of 3.2 mIU/mL (95% CI: 0.9–11.1) and 7.9 mIU/mL (95% CI: 4.2–14.8), respectively. Our findings demonstrated that PTB had a significant impact on the long‐term persistence of HBsAb after HepB vaccination. The very preterm infants (gestational age <32 weeks) and the preterm low birth weight infants (birth weight <2000 g) may be special populations that should be given priority for HepB booster vaccination. [ABSTRACT FROM AUTHOR]

المؤلفون: Husby, Anne Engtrø, Simpson, Melanie Rae, Dalbye, Rebecka, Larsen, Marit, Vanky, Eszter, Løvvik, Tone Shetelig

المصدر: Acta Obstetricia et Gynecologica Scandinavica; Jun2024, Vol. 103 Issue 6, p1092-1100, 9p

مصطلحات موضوعية: POLYCYSTIC ovary syndrome, CHILDBIRTH, PREMATURE labor, PREGNANCY complications, PREGNANCY outcomes, LABOR complications (Obstetrics)

مصطلحات جغرافية: ICELAND, NORWAY, SWEDEN

مستخلص: Introduction: Women with polycystic ovary syndrome (PCOS) have more pregnancy complications like gestational diabetes, hypertension, and preterm labor than other women. Metformin has been used in an attempt to improve pregnancy outcomes. Our study aims to explore childbirth experiences in women with PCOS compared with a reference population. It also explores the potential influence of metformin, obesity, pregnancy complications, and the duration and mode of birth on childbirth experiences. Material and methods: This study is a cohort study combining data from two randomized trials conducted in Norway, Sweden and Iceland. The PregMet2 study (ClinicalTrials.gov, NCT01587378) investigated the use of metformin vs. placebo in pregnant women with PCOS. The Labour Progression Study (ClinicalTrials.gov, NCT02221427) compared the WHO partograph to Zhang's guidelines for progression of labor and were used as the reference population. A total of 365 women with PCOS and 3604 reference women were included. Both studies used the Childbirth Experience Questionnaire (CEQ). Main outcome measures were total CEQ score and four domain scores. The CEQ scores were compared using Mann–Whitney U test for women in Robson group 1 with PCOS (n = 131) and reference women (n = 3604). CEQ scores were also compared between metformin‐treated (n = 180) and placebo‐treated (n = 185) women with PCOS, and for different subgroups of women with PCOS. Results: There was no difference in total CEQ score between women with PCOS and reference women—Wilcoxon–Mann–Whitney (WMW)‐odds 0.96 (95% confidence interval [CI] 0.78–1.17). We detected no difference in CEQ scores between the metformin‐ and placebo‐treated women with PCOS (WMW‐odds 1.13, 95% CI 0.89–1.43). Complications in pregnancy did not affect CEQ (WMW‐odds 1, 95% CI 0.76–1.31). Higher body mass index (WMW‐odds 0.75, 95% CI 0.58–0.96), longer duration of labor (WMW‐odds 0.69, 95% CI 0.49–0.96), and cesarean section (WMW‐odds 0.29, 95% CI 0.2–0.42) were associated with lower CEQ scores in women with PCOS. Conclusions: Women with PCOS experience childbirth similarly to the reference women. Metformin did not influence childbirth experience in women with PCOS, neither did pregnancy complications. Obesity, long duration of labor or cesarean section had a negative impact on childbirth experience. [ABSTRACT FROM AUTHOR]

: Copyright of Acta Obstetricia et Gynecologica Scandinavica is the property of Wiley-Blackwell and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

المؤلفون: Baas, Melanie A. M., Stramrood, Claire A. I., Dijksman, Lea M., Vanhommerig, Joost W., de Jongh, Ad, van Pampus, Mariëlle G.

المصدر: Acta Obstetricia et Gynecologica Scandinavica; Nov2023, Vol. 102 Issue 11, p1575-1585, 11p

مصطلحات موضوعية: EMDR (Eye-movement desensitization & reprocessing), FEAR of childbirth, PREGNANT women, INDUCED labor (Obstetrics), RANDOMIZED controlled trials, PREMATURE labor

مصطلحات جغرافية: NETHERLANDS

مستخلص: Introduction: Pregnant women with fear of childbirth display an elevated risk of a negative delivery experience, birth‐related post‐traumatic stress disorder, and adverse perinatal outcomes such as preterm birth, low birthweight, and postpartum depression. One of the therapies used to treat fear of childbirth is eye movement desensitization and reprocessing (EMDR) therapy. The purpose of the present study was to determine the obstetric safety and effectiveness of EMDR therapy applied to pregnant women with fear of childbirth. Material and methods: A randomized controlled trial (the OptiMUM‐study) was conducted in two teaching hospitals and five community midwifery practices in the Netherlands (www.trialregister.nl, NTR5122). Pregnant women (n = 141) with a gestational age between 8 and 20 weeks and suffering from fear of childbirth (i.e. sum score on the Wijma Delivery Expectations Questionnaire ≥85) were randomly allocated to either EMDR therapy (n = 70) or care‐as‐usual (CAU) (n = 71). Outcomes were maternal and neonatal outcomes and patient satisfaction with pregnancy and childbirth. Results: A high percentage of cesarean sections (37.2%) were performed, which did not differ between groups. However, women in the EMDR therapy group proved seven times less likely to request an induction of labor without medical indication than women in the CAU group. There were no other significant differences between the groups in maternal or neonatal outcomes, satisfaction, or childbirth experience. Conclusions: EMDR therapy during pregnancy does not adversely affect pregnancy or the fetus. Therefore, therapists should not be reluctant to treat pregnant women with fear of childbirth using EMDR therapy. [ABSTRACT FROM AUTHOR]

: Copyright of Acta Obstetricia et Gynecologica Scandinavica is the property of Wiley-Blackwell and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

المؤلفون: Jacobsson, Bo^1,2,3 (AUTHOR) bo.jacobsson@obgyn.gu.se, Simpson, Joe Leigh⁴ (AUTHOR), Norman, Jane (AUTHOR), Grobman, William (AUTHOR), Bianchi, Ana (AUTHOR), Munjanja, Stephen (AUTHOR), González, Catalina María Valencia (AUTHOR), Mol, Ben W. (AUTHOR), Shennan, Andrew (AUTHOR), FIGO Working Group for Preterm Birth (CORPORATE AUTHOR)

المصدر: International Journal of Gynecology & Obstetrics. Oct2021, Vol. 155 Issue 1, p1-4. 4p.

مصطلحات موضوعية: *CERVICAL cerclage, *PREMATURE labor, *CHILDBIRTH, *PLACENTA praevia, *INFERTILITY, *MULTIPLE pregnancy, *UMBILICAL cord clamping, *BEST practices, *PREMATURE infants

المؤلفون: Fox, Haylee¹ (AUTHOR), Callander, Emily² (AUTHOR) haylee.fox1@my.jcu.edu.au

المصدر: Journal of Paediatrics & Child Health. May2021, Vol. 57 Issue 5, p618-625. 8p.

مصطلحات موضوعية: *PREMATURE labor, *PREMATURE infants, *MOTHERS, *ECONOMIC aspects of diseases, *CHILDBIRTH

مصطلحات جغرافية: AUSTRALIA

مستخلص: Aim: To examine the differences in return to work time after childbirth; the differences in income; and the differences in out of pocket health-care costs between mothers who had a preterm birth and mothers who delivered a full term baby in Australia.Methods: Using administrative data, the length of time and 'risk' of returning to employment for mothers whose child was born premature relative to those whose child was born full term was reported. Multivariate linear regression models were constructed to assess the difference in maternal income and the differences in mean out-of-pocket costs between mothers who had a preterm birth and mothers who had a full term birth.Results: The mean length of time for mothers of babies born full term to return to work was 1.9 years and for mothers of preterm babies it was 2.8 years. Mothers of preterm babies had a significantly lower median income ah at 0-1, 2-3 and 4-5 years postpartum compared to mothers of full term babies. The adjusted mean out of pocket costs for health care paid by mothers who had a preterm birth was $1298 for those whose child was aged 32-36 weeks; and $2491 for those whose child was aged <32 weeks. This is in comparison to mothers of children born 37 weeks and over, whose mean out of pocket costs were $1059.Conclusion: Mothers who have a preterm birth have longer return to work time, a lower weekly income and also have higher out of pocket costs compared with mothers who have a full term birth. [ABSTRACT FROM AUTHOR]

المؤلفون: Champaloux, Eve P., Acosta, Anne Starks, Gray, Stacey T., Meyer, Tanya K., Bergmark, Regan W.

المصدر: Laryngoscope Investigative Otolaryngology; Oct2022, Vol. 7 Issue 5, p1322-1328, 7p

مصطلحات موضوعية: CHILDBIRTH, OTOLARYNGOLOGY, PREGNANCY complications, PREGNANCY, LIFE cycles (Biology), PREMATURE labor

مصطلحات جغرافية: UNITED States

مستخلص: Objectives: A paucity of literature exists about childbearing during otolaryngology residency. Pregnancy is a common part of many physician life cycles, but the timing of residency and the rigors of surgical training amplify the challenges. This study was designed to understand the experiences of childbearing otolaryngology residents and support them during this major life event. Unique challenges include long training, shortage of role models, combination surgical and clinical work, and higher rates of infertility. Study Design: Qualitative research. IRB exempt. Setting: United States. Methods: To capture modern perspectives, 16 current and former otolaryngology residents that experienced pregnancy and childbirth during residency in all four geographic regions of the United States in the past 10 years were recruited to participate in individual structured qualitative interviews. Results: Although there was significant training program and personal anxiety reported by childbearing otolaryngology residents, many surgeons experienced healthy pregnancies and postpartum recoveries with minimal disruption to clinical productivity and minimal disruption to their training programs. Multiple recurring themes were identified among the participants spanning the entire childbearing process: increased incidence of pregnancy complications and preterm labor, pregnancy stigma from leadership and coresidents, scheduling logistics regarding call and parental leave, and challenging transitions back to clinical work while navigating breastfeeding and childcare. Conclusion: There are actional recommendations that programs can address to make childbearing during residency accessible and acceptable. Understanding these challenges is an important step to encouraging childbearing residents to prosper in academic otolaryngology, increasing the diversity at the highest levels of the field. Level of Evidence: 4. [ABSTRACT FROM AUTHOR]

: Copyright of Laryngoscope Investigative Otolaryngology is the property of Wiley-Blackwell and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

المؤلفون: Barnea, Eytan R.^1,2 barnea@earlypregnancy.org, Muller, Martin^3,4, Di Simone, Nicoletta^5,6, Inversetti, Annalisa^5,6, Pacagnella, Rodolfo⁷, Borovac-Pinheiro, Anderson⁶, Nicholson, Wanda⁸

المصدر: International Journal of Gynecology & Obstetrics. 2023 Supplement, Vol. 163, p34-39. 6p.

مصطلحات موضوعية: *DELIVERY (Obstetrics), *LABOR (Obstetrics), *PREMATURE labor, *CESAREAN section, *HIGH-risk pregnancy, *MATERNITY nursing

مستخلص: Childbirth is an intense event in which decisions may need to be made in seconds to guarantee the health of both mother and newborn. Despite health systems and care approaches varying widely according to real-life scenarios, availability of facilities, beliefs, resources, staff, and geography, among others, optimal outcomes should be ensured worldwide. Triaging low-risk pregnancies from high-risk pregnancies is the first step to ensure proper allocation of resources. From this need, we developed FIGO's Prep-For-Labor triage methods, a series of 2-minute labor and delivery bundles of care, with special regard given to low-and middle-income countries and rural settings. Around 80% of women, once properly triaged, can pursue vaginal delivery with minimal intervention, while those at risk can either be managed on site or transferred promptly to an advanced care site. FIGO's bundles of care and good practice recommendations for labor and delivery and immediate newborn triage cover four clinical scenarios: (1) preterm labor; (2) induced or spontaneous labor at term; (3) cesarean delivery; and (4) newborn care. From rapid triage of the mother (low vs high risk) to the list of required equipment, description of skilled staff, and coordination of resources, the recommendations for care are introduced across these four areas in this overview article. Implementing the proposed management steps described in each summary can improve maternal and neonatal outcomes. [ABSTRACT FROM AUTHOR]

المؤلفون: Giang, Hoang Thi Nam^1,2 htngiang@ud.edu.vn, Bechtold‐Dalla Pozza, Susanne^1,3, Tran, Hoang Thi^2,4,5, Ulrich, Sarah^1,6, Bechtold-Dalla Pozza, Susanne^7,8

المصدر: Acta Paediatrica. Apr2019, Vol. 108 Issue 4, p630-636. 7p.

مصطلحات موضوعية: *PREMATURE labor, *STILLBIRTH, *CHILDBIRTH

مصطلحات جغرافية: VIETNAM, DA Nang (Vietnam)

مستخلص: Aim: Little is known about the rate of stillbirths, preterm births and associated risk factors in resource-limited settings like Vietnam. This study reports those rates for Da Nang, which is one of the largest cities in central Vietnam.Methods: Data on 20 762 births including stillbirths and preterm births and associated risk factors were prospectively collected from health facilities from April 2015 to March 2016.Results: The data represented 85% of the total births in Da Nang during the study period, and a stillbirth rate of 9.7 per 1000 live births was recorded. The preterm rate for live births was just under 5%. Independent factors associated with an increased risk of stillbirth and preterm births were mothers aged 35 plus, working as farmers, living in the provinces and a history of abortion. Mothers under 20 years with previous preterm births faced a higher risk of another preterm birth.Conclusion: The stillbirth and premature birth rates in Da Nang were higher than rates in high-income countries. Developing registration programmes in Vietnam will provide improved data that will enable researchers and policymakers to identify strategies to reduce the number of stillbirths and premature births. [ABSTRACT FROM AUTHOR]

المؤلفون: Bertholdt, Charline^1,2 charline.bertholdt@gmail.com, Menard, Sophie¹, Delorme, Pierre^1,3, Lamau, Marie‐Charlotte¹, Goffinet, François^1,3, Le Ray, Camille^1,3, Lamau, Marie-Charlotte⁴ (AUTHOR)

المصدر: Acta Obstetricia et Gynecologica Scandinavica. May2018, Vol. 97 Issue 5, p608-614. 7p.

مصطلحات موضوعية: *CESAREAN section, *PREMATURE labor, *PREGNANCY complications, *GESTATIONAL age, *CHILDBIRTH, *COMPARATIVE studies, *PREMATURE infants, *RESEARCH methodology, *MEDICAL cooperation, *RESEARCH, *SURGICAL complications, *LOGISTIC regression analysis, *EVALUATION research, *RETROSPECTIVE studies

مستخلص: Introduction: At the same time as survival is increasing among premature babies born before 26 weeks of gestation, the rates of cesarean deliveries before 26 weeks is also rising. Our purpose was to compare the frequency of intraoperative adverse events during cesarean deliveries in two gestational age groups: 24-25 weeks and 26-27 weeks.Material and Methods: This single-center retrospective cohort study included all women with cesarean deliveries performed before 28+0 weeks from 2007 through 2015. It compared the frequency of intraoperative adverse events between two groups: those at 24-25 weeks of gestation and at 26-27 weeks. Intraoperative adverse events were a classical incision, transplacental incision, difficulty in fetal extraction (explicitly mentioned in the surgical report), postpartum hemorrhage (≥500 mL of blood loss), and injury to internal organs. A composite outcome including at least one of these events enabled us to analyze the risk factors for intraoperative adverse events with univariate and multivariable analysis. Stratified analyses by the indication for the cesarean were performed.Results: We compared 74 cesarean deliveries at 24-25 weeks of gestation and 214 at 26-27 weeks. Intraoperative adverse events occurred at higher rates in the 24-25-week group (63.5 vs. 30.8%, p < 0.001). After adjustment for confounding factors, this group remained at significantly higher risk of intraoperative adverse events [adjusted odds ratio 5.04 (2.67-9.50)], even after stratification by indication for the cesarean.Conclusion: These results should help obstetricians and women making decisions about cesarean deliveries at these extremely low gestational ages. [ABSTRACT FROM AUTHOR]

المؤلفون: Castañon, A¹, Landy, R¹, Brocklehurst, P², Evans, H³, Peebles, D², Singh, N⁴, Walker, P³, Patnick, J⁵, Sasieni, P¹

المصدر: BJOG: An International Journal of Obstetrics & Gynaecology. Aug2015, Vol. 122 Issue 9, p1191-1199. 9p. 1 Diagram, 2 Charts, 1 Graph.

مصطلحات موضوعية: *RISK factors in premature labor, *SURGICAL excision, *CERVICAL intraepithelial neoplasia, *CHILDBIRTH, *COLPOSCOPY, *CASE-control method, *SUBSEQUENT pregnancy

مستخلص: Objective To explore whether the increased risk of preterm birth following treatment for cervical disease is limited to the first birth following colposcopy. Design Nested case-control study. Setting Twelve NHS hospitals in England. Population All nonmultiple births from women selected as cases or controls from a cohort of women with both colposcopy and a hospital birth. Cases had a preterm (20-36 weeks of gestation) birth. Controls had a term birth (38-42 weeks) and no preterm. Methods Obstetric, colposcopy and pathology details were obtained. Main outcome measures Adjusted odds ratio of preterm birth in first and second or subsequent births following treatment for cervical disease. Results A total of 2798 births (1021 preterm) from 2001 women were included in the analysis. The risk of preterm birth increased with increasing depth of treatment among first births post treatment [trend per category increase in depth, categories <10 mm, 10-14 mm, 15-19 mm, ≥20 mm: odds ratio ( OR) 1.23, 95% confidence interval (95% CI) 1.12-1.36, P < 0.001] and among second and subsequent births post treatment (trend OR 1.34, 95% CI 1.15-1.56, P < 0.001). No trend was observed among births before colposcopy ( OR 0.98, 95% CI 0.83-1.16, P = 0.855). The absolute risk of a preterm birth following deep treatments (≥15 mm) was 6.5% among births before colposcopy, 18.9% among first births and 17.2% among second and subsequent births post treatment. Risk of preterm birth (once depth was accounted for) did not differ when comparing first births post colposcopy with second and subsequent births post colposcopy (adjusted OR 1.15, 95% CI 0.89-1.49). Conclusions The increased risk of preterm birth following treatment for cervical disease is not restricted to the first birth post colposcopy; it remains for second and subsequent births. These results suggest that once a woman has a deep treatment she remains at higher risk of a preterm birth throughout her reproductive life. Tweetable abstract Risk of preterm birth following large treatments for cervical disease remains for second and subsequent births. [ABSTRACT FROM AUTHOR]