دورية أكاديمية
Clinical Implementation of Pharmacogenetic Testing in a Hospital of the Spanish National Health System: Strategy and Experience Over 3 Years
| العنوان: | Clinical Implementation of Pharmacogenetic Testing in a Hospital of the Spanish National Health System: Strategy and Experience Over 3 Years |
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| المؤلفون: | Borobia Pérez, Alberto M., Dapia, Irene, Tong, Hoi Y., Arias, Pedro, Muñoz, Mario, Tenorio, Jair, Hernández, Rafael, García García, Irene, Gordo, Gema, Ramírez García, Elena, Frías Iniesta, Jesús A., Lapunzina, Pablo, Carcas Sansuán, Antonio Javier |
| المساهمون: | UAM. Departamento de Farmacología |
| بيانات النشر: | Wiley Open Access |
| سنة النشر: | 2024 |
| المجموعة: | Universidad Autónoma de Madrid (UAM): Biblos-e Archivo |
| مصطلحات موضوعية: | individualization, pharmacogenetics, precision medicine, Farmacia |
| الوصف: | In 2014, we established a pharmacogenetics unit with the intention of facilitating the integration of pharmacogenetic testing into clinical practice. This unit was centered around two main ideas: i) individualization of clinical recommendations, and ii) preemptive genotyping in risk populations. Our unit is based on the design and validation of a single nucleotide polymorphism (SNP) microarray, which has allowed testing of 180 SNPs associated with drug response (PharmArray), and clinical consultation regarding the results. Herein, we report our experience in integrating pharmacogenetic testing into our hospital and we present the results of the 2,539 pharmacogenetic consultation requests received over the past 3 years in our unit. The results demonstrate the feasibility of implementing pharmacogenetic testing in clinical practice within a national health system |
| نوع الوثيقة: | article in journal/newspaper |
| وصف الملف: | application/pdf |
| اللغة: | English |
| العلاقة: | Clinical and Translational Science; https://doi.org/10.1111/cts.12526Test; Clinical And Translational Science 11.2 (2018): 189-199; 1752-8054 (print); 1752-8062 (online); http://hdl.handle.net/10486/710583Test; 189; 199; 11 |
| DOI: | 10.1111/cts.12526 |
| الإتاحة: | https://doi.org/10.1111/cts.12526Test http://hdl.handle.net/10486/710583Test |
| حقوق: | © 2017 ASCPT ; Reconocimiento – NoComercial ; openAccess |
| رقم الانضمام: | edsbas.7607DFA0 |
| قاعدة البيانات: | BASE |
| DOI: | 10.1111/cts.12526 |
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