المؤلفون: Wen, D., Shen, Z., Qi, X., Wu, X.‐F.

المساهمون: Natural Science Foundation of Zhejiang Province

المصدر: European Journal of Organic Chemistry ; volume 2022, issue 42 ; ISSN 1434-193X 1099-0690

الوصف: Dimethyl carbonate (DMC), a non‐toxic liquid, which shows diverse and tunable reactivity in organic synthesis. Herein, we report a nice study on using DMC as both solvent and reactant in palladium‐catalyzed intramolecular Heck/Carbonylation for the synthesis of functionalized isoquinoline‐1,3‐diones and oxindoles. To avoid the usage of toxic CO gas, formic acid is employed as the CO source, and a variety of functionalized isoquinoline‐1,3‐diones and oxindoles were obtained in very good yields.

الإتاحة: https://doi.org/10.1002/ejoc.202200971Test

المؤلفون: Yang, J., Chen, J., Wu, X.‐F., Song, N.‐J., Li, Q., Qiao, D., Zhang, J.‐Y., Song, N.‐H.

المصدر: Andrology ; volume 2, issue 5, page 729-733 ; ISSN 2047-2919 2047-2927

الوصف: Summary We conducted this study to investigate whether glans‐reconstruction with preputial flap would be more helpful for post‐operative restoration of patients' sexual potency than primary closure. From 2007 to 2013 at four centres, 46 cases reconstructed with preputial flap and 59 with primary closure were selected for the investigation from 142 consecutive cases of superficial glans cancer, with the largest diameter of lesion ≤2.5 cm, who undergoing glans‐preserving surgery ( GPS ). Subjective evaluation for patients' sexual performance was investigated using the International Index of Erectile Function‐15. Objective evaluation was carried out by the Audio Visual Sexual Stimulation test with RigiScan‐Plus. The degree of satisfaction for penile appearance and patients' confidence and partners' acceptability for intercourse were evaluated by 5‐point scales. Patients with preputial flap reconstruction showed significant better performance in three domains (orgasmic function, intercourse satisfaction and overall satisfaction, all p < 0.05) and significantly higher ratios of appearance satisfaction (78.3% vs. 57.6%, p = 0.026) and intercourse confidence (69.6% vs. 49.2%, p = 0.035) compared with those undergoing primary closure at post‐operative month 6 ends. Their sexual partners in the preputial flap group also exhibited significantly higher ratios of appearance satisfaction than in the primary closure group (67.4% vs. 42.4%, p = 0.011). Reconstruction with preputial flap contributes to a more acceptable cosmetic appearance of the penis and minimizes post‐operative negative psychological impediments. Patients can benefit more from reconstruction with preputial flap than primary closure. Glans‐reconstruction with preputial flap should be considered the primary reconstruction technique in GPS .

الإتاحة: https://doi.org/10.1111/j.2047-2927.2014.00239Test.x

المؤلفون: Du, Y.s., Li, C. R., Cheng, G., Sun, Y. Z., Wu, X. F., Yao, Q. R.

المصدر: ChemInform ; volume 47, issue 48 ; ISSN 0931-7597 1522-2667

الوصف: The 773 K isothermal section of the title system is investigated by XRD, SEM, DSC, and EDS techniques.

الإتاحة: https://doi.org/10.1002/chin.201648006Test

المؤلفون: Du, Y. S., Li, C. R., Cheng, G., Sun, Y. Z., Wu, X. F., Li, L., Rao, G. H.

المصدر: ChemInform ; volume 46, issue 49 ; ISSN 0931-7597 1522-2667

الوصف: The solid state phase equilibria in the title system are characterized by powder XRD, FESEM, DSC, and EDS.

الإتاحة: https://doi.org/10.1002/chin.201549013Test

المؤلفون: Sun, C. X., Li, M. Q., Gao, X. X., Liu, L. N., Wu, X. F., Zhou, J. H.

المساهمون: Mock, H.‐P., National Natural Science Foundation of China, Fundamental Research Funds of the Central University

المصدر: Plant Biology ; volume 18, issue S1, page 120-129 ; ISSN 1435-8603 1438-8677

الوصف: Clarification of the metabolic mechanisms underlying multi‐stress responses in plants will allow further optimisation of crop breeding and cultivation to obtain high yields in an increasingly variable environment. Using NMR metabolomic techniques, we examined the metabolic responses of maize plants grown under different conditions: soil drought, soil salinity, heat and multiple concurrent stresses. A detailed time‐course metabolic profile was also performed on maize plants sampled 1, 3 and 7 days after initiation of soil drought and heat stress. The metabolic profile of maize plants subjected to soil drought was more similar to plants exposed to salt stress than to heat‐stressed plants. Drought‐stressed maize plants subjected to salt or heat stress showed distinct integrated metabolic profiles compared with those exposed to either stressor individually. These differences show the considerable metabolic plasticity of maize in response to different growth conditions. Moreover, glucose, fructose, malate, citrate, proline, alanine, aspartate, asparagine, threonine and one unknown compound fluctuated obviously between maize plants grown in controlled growth cabinet and a natural regime. These changes were associated with the TCA cycle and core nitrogen metabolism, and could be related to their multiple functions during plant growth. The evident stress‐induced trajectory of metabolic changes in maize indicated that the primary metabolic responses to soil drought, heat and combined drought and heat stresses occurred in a time‐dependent manner. Plasticity at the metabolic level may allow maize plants to acclimatise their metabolic ranges in response to changing environmental conditions.

الإتاحة: https://doi.org/10.1111/plb.12305Test

المؤلفون: Liu, J. M., Cai, X. Z., Lin, J. J., Fu, Z. Q., Yang, G. Z., Shi, F. H., Cai, Y. M., Shen, W., Taylor, M. G., Wu, X. F.

المصدر: Parasite Immunology ; volume 26, issue 8-9, page 351-358 ; ISSN 0141-9838 1365-3024

الوصف: SUMMARY A 600 bp DNA fragment was amplified by PCR from an adult Schistosoma japonicum cDNA library. Sequence analysis confirmed that this fragment contained an S. japonicum Chinese mainland strain fatty acid binding protein (Sj14FABP) gene. This gene was subsequently expressed in Escherichia coli (E. coli) and in Baculovirus/silkworm systems. The recombinant protein from E. coli was a 41 kDa GST fusion protein (rSj14/GST), which could be purified by glutathione agarose affinity chromatography, with a yield of 25 mg/L E. coli culture. The recombinant protein from the Baculovirus/silkworm system was an 18 kDa fusion protein (rSj14/His), which could be purified by Ni‐NTA resin chromatography column with a yield of 3·5 mg per silkworm larva. Both rSj14/GST and rSj14/His could be recognized by S. japonicum‐ infected mouse sera and anti‐rSj14/GST mouse sera in Western blotting. The purified recombinant protein was immunogenic in mice, rats and sheep, and 34·3%, 31·9% and 59·2% worm reductions, respectively, were obtained in vaccinated Kunming mice, Wistar rats and sheep vaccinated with Sj14/GST, compared to non‐vaccinated control groups. Worm reductions of 48·8% and 49·0% were recorded in Balb/c mice immunized with Sj14/His, compared to non‐vaccinated and BCG‐vaccinated groups, respectively. These results indicate that rSj14FABP is a promising candidate vaccine for schistosomiasis japonica, particularly as in the rat and sheep vaccination experiments, no adjuvant was used.

الإتاحة: https://doi.org/10.1111/j.0141-9838.2004.00720Test.x

المؤلفون: Wu, X.‐F., Dzenis, Y.A., Zou, W.‐S.

المصدر: ZAMM - Journal of Applied Mathematics and Mechanics / Zeitschrift für Angewandte Mathematik und Mechanik ; volume 83, issue 6, page 419-422 ; ISSN 0044-2267 1521-4001

الوصف: A closed‐form solution is obtained for the interfacial edge crack between two bonded dissimilar orthotropic strips loaded by antiplane point loading in form of screw dislocation or line force. Conformal mapping and existing dislocation solutions are utilized for constructing the fundamental solution of the problem. The stress intensity factor (SIF) and the energy release rate (ERR) are obtained explicitly.

الإتاحة: https://doi.org/10.1002/zamm.200310063Test

المؤلفون: Li, D. Y., Wu, X. F., Ko, T.

المصدر: physica status solidi (b) ; volume 154, issue 1, page 85-96 ; ISSN 0370-1972 1521-3951

الوصف: The behavior of the phase transformation in equiatomic TiNi alloy during thermal cycling under applied stresses is studied by measuring the electical resistivity and investigating the diffuse streak diffraction of electron and the X‐ray diffraction. The results show that the stress has a strong effect on the lattice instability. The tensile stress promotes the softening of phonon modes which relate to the nucleations of the R phase and the martensitic phase so that the tensile stress is favourable for the formation of the R phase and martensitic phase, while the compression stress has negative effects. The investigation shows that the effect of stress on 〈111〉 longitudinal phonon mode is larger than that on 〈110〉 transversal phonon mode. The tensile stress enhances particularly the softening of 〈111〉 longitudinal phonon mode which corresponds mostly to the R phase transformation, but the compression stress is unfavourable for it. It is identified that the diffuse streak diffraction patterns of electron associated with more R phase induced by the tensile stress arises from the softening of 〈111〉 longitudinal phonon mode.

الإتاحة: https://doi.org/10.1002/pssb.2221540107Test