التفاصيل البيبلوغرافية
| العنوان: |
Association of left ventricular end‐diastolic pressure with mortality in patients undergoing percutaneous coronary intervention for acute coronary syndromes |
| المؤلفون: |
Leistner, David M., Dietrich, Steven, Erbay, Aslihan, Steiner, Julia, Abdelwahed, Youssef, Siegrist, Patrick T., Schindler, Matthias, Skurk, Carsten, Haghikia, Arash, Sinning, David, Riedel, Matthias, Landmesser, Ulf, Stähli, Barbara E. |
| المصدر: |
Catheterization and Cardiovascular Interventions ; volume 96, issue 4 ; ISSN 1522-1946 1522-726X |
| بيانات النشر: |
Wiley |
| سنة النشر: |
2020 |
| المجموعة: |
Wiley Online Library (Open Access Articles via Crossref) |
| الوصف: |
Objectives This study sought to investigate the relation between left ventricular end‐diastolic pressure (LVEDP) and outcomes in patients undergoing percutaneous coronary intervention (PCI) for acute coronary syndromes (ACS). Background Risk stratification in ACS patients is important. Data on the role of LVEDP in the prognostication of ACS patients are scarce. Methods A total of 1,410 patients undergoing PCI for ACS and with available data on LVEDP were divided according to LVEDP tertiles (lowest tertile: ≤13 mmHg, intermediate tertile: 14–20 mmHg, and highest tertile: >20 mmHg). The primary endpoint was all‐cause mortality at a median follow‐up of 246 [28–848] days. Results Median LVEDP was 16 (11–22) mmHg. All‐cause mortality was 2.8%, 4.5%, and 15.0% in the lowest, the intermediate, and the highest LVEDP tertile groups ( p < .001), respectively. Belonging to the highest LVEDP tertile was associated with an increased risk of all‐cause mortality (adjusted hazard ratio [HR] = 2.66, 95% confidence interval [CI] [1.30, 5.47], p = .008). By receiver operating characteristic curve analysis, the optimal cut‐off value for predicting all‐cause mortality was 20 mmHg (sensitivity 68.3%, specificity 72.5%). There was no differential effect of LVEDP on mortality in patients with and without LV dysfunction (interaction p = .23) or ST‐elevation myocardial infarction as index ACS event (interaction p = .86). Conclusions In patients undergoing PCI for ACS, LVEDP was independently related with mortality. Hence, LVEDP should be incorporated into early risk stratification and clinical decision making of ACS patients. |
| نوع الوثيقة: |
article in journal/newspaper |
| اللغة: |
English |
| DOI: |
10.1002/ccd.28839 |
| الإتاحة: |
https://doi.org/10.1002/ccd.28839Test |
| حقوق: |
http://onlinelibrary.wiley.com/termsAndConditions#vorTest |
| رقم الانضمام: |
edsbas.75FAD9B4 |
| قاعدة البيانات: |
BASE |
