المؤلفون: Lakhbir Kaur Dhaliwal, Nalini Gupta, Radhika Srinivasan, A. Rajwanshi, Raje Nijhawan, Palash Dey, Niranjan Khandelwal

المصدر: Cytopathology. 23:300-307

مصطلحات موضوعية: Pathology, medicine.medical_specialty, Histology, Sertoli–Leydig cell tumour, medicine.diagnostic_test, business.industry, Sertoli cell tumour, General Medicine, Granulosa cell tumour, medicine.disease, Malignancy, Pathology and Forensic Medicine, Cytology, Biopsy, medicine, Mucinous carcinoma, Fibroma, business

الوصف: N. Gupta, A. Rajwanshi, L. K. Dhaliwal, N. Khandelwal, P. Dey, R. Srinivasan and R. Nijhawan Fine needle aspiration cytology in ovarian lesions: an institutional experience of 584 cases Objective: To assess the diagnostic value of fine needle aspiration cytology (FNAC) in ovarian lesions. Methods: This was a retrospective study of ultrasound-guided (US) FNAC of 584 ovarian lesions from January 1998 to July 2010. The lesions were categorized into non-neoplastic lesions, neoplastic lesions and inadequate aspirates. The results were compared with the corresponding histopathology whenever available. Results: Of the 584 lesions, 180 (30.8%) were reported as non-neoplastic (48 non-specific inflammation, 11 tuberculosis, 63 functional cysts and 58 endometriotic cysts), 249 (42.6%) as neoplastic (81 benign lesions/tumours and 168 malignant) and 155 (26.5%) as inadequate. Based on the subsequent histopathology, which was available in 121 (20.7%), the cases were divided into those that were concordant and discordant. Concordant cases comprised 92/121 (76%), including 28 non-neoplastic lesions (seven non-specific inflammation, nine functional cysts and 12 endometriotic cysts), 42 surface epithelial tumours (13 benign and 29 malignant), 10 germ cell tumours (five mature cystic teratomas and five mixed germ cell tumours), seven sex-cord stromal tumours (three granulosa cell tumours, one sclerosing stromal tumour, one strumal leutoma, one Sertoli Leydig cell tumour and one malignant Sertoli cell tumour) and five miscellaneous lesions (one plasma cell tumour, two leiomyosarcomas and two cases of necrosis). Discordant cases comprised 29/121 (24%) (21were inconclusive or inadequate on cytology), including four endometriotic cysts, 14 surface epithelial tumours (one cystadenofibroma, one borderline mucinous tumour and 12 carcinomas), five germ cell tumours (two immature teratomas and three mature cystic teratomas), two thecomas, one fibroma, one sclerosing stromal tumour, one fibrosarcoma and one myxoma. FNAC sensitivity for a diagnosis of malignancy was 85.7%, specificity 98.0%, positive predictive value 97.7%, negative predictive value 87.7% and accuracy 92.0%, if 21 inconclusive/inadequate FNACs were excluded; with the latter taken as false negatives, sensitivity was 73.7% and accuracy 76.0%. Conclusion: FNAC has a high specificity for diagnosis of ovarian/adnexal lesions but greater experience is required for the accurate subtyping of neoplasms and sensitivity is limited by inconclusive/inadequate results.

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_________::cc880ca46ba4afc253a7b5a5ad6b9cc1Test
https://doi.org/10.1111/j.1365-2303.2011.00896.xTest

المؤلفون: Arvind Rajwanshi, Pranab Dey, Tarak Banik, Nalini Gupta, Lakhbir Kaur Dhaliwal

المصدر: Diagnostic Cytopathology. 40:342-345

مصطلحات موضوعية: endocrine system, Pathology, medicine.medical_specialty, Histology, Adolescent, Sclerosing stromal tumor, Ovarian stroma, Granulosa cell, Biopsy, Fine-Needle, Ovary, Pathology and Forensic Medicine, Benign tumor, Young Adult, Fine needle aspiration cytology, Call-Exner bodies, Biopsy, medicine, Humans, Sex Cord-Gonadal Stromal Tumors, Ovarian Neoplasms, Sclerosis, medicine.diagnostic_test, business.industry, General Medicine, Anatomy, medicine.disease, medicine.anatomical_structure, Female, business

الوصف: Sclerosing stromal tumor (SST) of the ovary is a distinct subtype of sex cord-stromal tumor, which is derived from the ovarian stroma and, in turn, from the sex cords of the embryonic gonads. It is a benign tumor, predominantly, unilateral in nature and mostly involves the right side of the ovary. Histopathological features are characteristic and are well described in the literature; however to the best of our knowledge fine needle aspiration cytology (FNAC) has not been described previously. We present FNAC findings in a series of three cases of SST and discuss the cytomorphological features. We have described Call-Exner like bodies in one of our cases and hence, suggest that these may not be an exclusive feature of granulosa cell tumor.

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c5cbf701a83c70b7c7066bc9d478a625Test
https://doi.org/10.1002/dc.21639Test

المؤلفون: Palash Dey, Vanita Suri, A. Rajwanshi, Radhika Srinivasan, Nishkarsh Gupta, Raje Nijhawan, Lakhbir Kaur Dhaliwal

المصدر: Cytopathology. 22:189-194

مصطلحات موضوعية: Pathology, medicine.medical_specialty, Histology, medicine.diagnostic_test, Cytohistological correlation, business.industry, Not Otherwise Specified, Bethesda system, hemic and immune systems, Cervical cytology, General Medicine, Atypical Squamous Cells, Cervical intraepithelial neoplasia, medicine.disease, eye diseases, Pathology and Forensic Medicine, Squamous intraepithelial lesion, Medicine, business

الوصف: N. Gupta, R. Srinivasan, R. Nijhawan, A. Rajwanshi, P. Dey, V. Suri and L. Dhaliwal Atypical squamous cells and low-grade squamous intraepithelial lesion in cervical cytology: cytohistological correlation and implication for management in a low-resource setting Objectives: To perform an audit of all cervical smears reported as atypical squamous cells (ASC) and low-grade squamous intraepithelial lesion (LSIL) as in the Bethesda system (TBS) 2001, and determine their histological follow-up and outcome when available, in order to define the threshold for colposcopic referral. Material and methods: A total of 25 203 cervical smears were screened over a period of 3 years (January 2006 – December 2008) and all ASC and LSIL smears were reviewed with the corresponding histological follow-up. All cervical intraepithelial neoplasia (CIN) grade 2 lesions and above (CIN2+) were considered as clinically significant lesions for analysis. Results: Out of 25 203 cervical smears, 424 (1.7%) were reported as ASC and 113 (0.4%) as LSIL. Additionally, three were reported as atypical cells, not otherwise specified. The ASC : SIL ratio was 2.18 : 1. Follow-up histology was available in 153 (36.8%) of the ASC cases and revealed CIN2+ lesions in 22 (14.4%). Follow-up histology was available in 50 (44.2%) of LSIL cases and revealed clinically significant abnormalities in five (10%), all of which were CIN2. CIN3 and invasive squamous carcinomas were seen in 5.9% and 1.4%, respectively, of cases of ASC, and not seen in LSIL. Reclassification of ASC smears into ASC-US (ASC-undetermined significance) and ASC-H (ASC- high grade SIL not excluded) revealed ASC-H in 2.6% of all ASC smears, with a clinically significant outcome in 45.4%. Conclusion: In a low-resource setting where human papillomavirus testing is unaffordable, the threshold for colposcopic referral and follow-up histology should be ASC rather than SIL.

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_________::9cbd2ce7a6337ec2cdb9a8824034997cTest
https://doi.org/10.1111/j.1365-2303.2010.00780.xTest

المؤلفون: Lakhbir Kaur Dhaliwal, Indu Gupta, Kamala Rani Khera

المصدر: Asia-Oceania Journal of Obstetrics and Gynaecology. 14:177-180

مصطلحات موضوعية: Adult, Male, Infertility, medicine.medical_specialty, Abortion, Septic, Abortion, Secondary infertility, Uterine abnormality, Sepsis, Pregnancy, Primary infertility, medicine, Humans, Prospective Studies, Hysterosalpingography, Fallopian Tubes, reproductive and urinary physiology, Gynecology, medicine.diagnostic_test, Obstetrics, business.industry, Age Factors, Obstetrics and Gynecology, medicine.disease, Infertility clinic, Female, business, Infertility, Female

الوصف: A total of 848 couples attended our infertility clinic over a period of 4 years. Two hundred forty-eight complained of secondary infertility of which 63.7% had an abnormal hysterosalpingographic finding. The abnormal hysterosalpingography (HSG) was seen to increase with an increase in age and duration of infertility. Of the subjects with previous viable delivery, 41.6% had normal HSG whereas 38.1% with previous spontaneous abortion and only 11.5% with previous induced abortion had a normal HSG. Uterine abnormality was 2 and a half times in the cases with spontaneous abortion than in cases who had previous viable delivery. Tubal blocks were detected more in secondary infertility group whereas congenital uterine abnormalities were more in primary infertility group. Bilateral tubal blocks were more common in cases who had an abortion followed by sepsis.

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::358951be944f0f850a65e73c542598f6Test
https://doi.org/10.1111/j.1447-0756.1988.tb00091.xTest

المؤلفون: Niranjan Khandelwal, Akshay Kumar Saxena, Chirag Kamal Ahuja, Lakhbir Kaur Dhaliwal, Manphool Singhal

المصدر: Journal of Clinical Ultrasound. 38:509-511

مصطلحات موضوعية: Adult, medicine.medical_specialty, Diagnosis, Differential, Pregnancy, Pelvic inflammatory disease, medicine, Humans, Radiology, Nuclear Medicine and imaging, Ultrasonography, Gynecology, Heterotopic pregnancy, Rupture, Spontaneous, Ectopic pregnancy, Intrauterine Contraceptive Devices, Cesarean Section, business.industry, Obstetrics, Ultrasound, Pregnancy Outcome, medicine.disease, Ectopic/Tubal, Female, Pregnancy, Tubal, business, Surgical interventions

الوصف: Heterotopic pregnancy, ie, combined intrauterine and extrauterine (ectopic) pregnancy, is a rare clinical entity that may present with acute abdominal catastrophy. Most of cases reported in literature are a consequence of medical or surgical interventions like assisted reproductive techniques, tubal surgeries, intrauterine contraceptive devices, or pelvic inflammatory disease. Heterotopic pregnancy occurring spontaneously is extremely uncommon. We describe the sonographic appearance of spontaneous heterotopic pregnancy with ruptured ectopic tubal pregnancy. © 2010 Wiley Periodicals, Inc. J Clin Ultrasound, 2010

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cc952f668fc59f90e14f50908a4ccfd6Test
https://doi.org/10.1002/jcu.20715Test

المؤلفون: Gupta An, Indu Gupta, Kamla Rani Khera, Lakhbir Kaur Dhaliwal

المصدر: Asia-Oceania Journal of Obstetrics and Gynaecology. 13:65-67

مصطلحات موضوعية: medicine.medical_specialty, medicine.diagnostic_test, Obstetrics, business.industry, nutritional and metabolic diseases, Obstetrics and Gynecology, Fallopian Tube Diseases, Diagnostic evaluation, Hysterosalpingography, medicine, Humans, Female, Laparoscopy, Radiology, business, Infertility, Female, Fallopian Tubes

الوصف: Diagnostic findings obtained by hysterosalpingography and laparoscopy are compared in 200 cases. In 45.5% cases the results are in agreement. False positive results by HSG are found in 21.5% of subjects and 15% were false negative findings on HSG films. HSG holds a definite place in the initial diagnostic evaluation of the tubal factor in infertile women.

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ef158591758db21655662cc9293bce11Test
https://doi.org/10.1111/j.1447-0756.1987.tb00011.xTest

المؤلفون: Saji Saraswathy Gopalan, A G Das, Lakhbir Kaur Dhaliwal

المصدر: The Australian and New Zealand Journal of Obstetrics and Gynaecology. 36:135-139

مصطلحات موضوعية: medicine.medical_specialty, Pregnancy Trimester, Third, Perinatal outcome, Ultrasonography, Prenatal, Embryonic and Fetal Development, Pregnancy, Placenta, medicine, Humans, Prospective Studies, Gynecology, Fetus, Obstetrics, business.industry, Incidence (epidemiology), Pregnancy Outcome, Obstetrics and Gynecology, General Medicine, medicine.disease, Abortion, Threatened, Confidence interval, Low-Lying Placenta, medicine.anatomical_structure, Pregnancy Trimester, Second, embryonic structures, Gestation, Female, business

الوصف: EDITORIAL COMMENT: We accepted this paper for publication because it provides some useful information on the outcome of a small series of women with threatened abortion who were followed carefully with serial ultrasonographic estimations. Although the results were excellent in comparison with the control series it should be noted that patients were excluded if delivery occurred before 28 weeks' gestation. This is an important point because threatened miscarriage may result in an increased incidence of premature births between 20–28 weeks' gestation and an increased incidence of fetal malformations in those pregnancies that terminate before 28 weeks. Nonetheless it is important to be able to reassure women who have had a threat to abort that if the pregnancy continues past 28 weeks there is no increased incidence of either major fetal malformations or perinatal deaths. A higher incidence of placenta praevia in patients with threatened miscarriage could also be hidden in a series excluding all those patients delivered before 28 weeks if those with placenta praevia were to deliver before this time. Other studies have also shown that pregnancies complicated by threatened abortion which proceed beyond 28 weeks' gestation have no significant increase in the incidence of prematurity, fetal growth retardation or major fetal malformations. (A) Evans JH, Beischer NA. The prognosis of threatened abortion. Med J Aust 1970; 2: 165–168. Summary: The present study was conducted with the aim to find out the effect of threatened abortion in the current pregnancy on the subsequent perinatal outcome and follow the growth pattern of the fetuses of such complicated pregnancies. The study group consisted of 55 women with threatened abortion and 55 women with normal pregnancies formed the control group. Most of the patients presented at 6–12 weeks' gestation. The fetal growth was monitored by both clinical as well as ultrasound (USG) parameters. The mean growth rates were almost identical throughout gestation. The mean values of each parameter of the study group were found lying within 95% confidence limit values of their control group. The apparent increased incidence of low lying placenta in early pregnancy probably contributed to threatened abortion. There was no significant difference in preterm delivery, low birth-weight and overall perinatal outcome.

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fe0fba089d3f9f495659da58630ef8caTest
https://doi.org/10.1111/j.1479-828x.1996.tb03269.xTest

المؤلفون: R. Gita, Lakhbir Kaur Dhaliwal, Sarala Gopalan

المصدر: International Journal of Gynecology & Obstetrics. 33:317-320

مصطلحات موضوعية: Adult, Pregnancy, Fetus, medicine.medical_specialty, business.industry, Obstetrics, Suture Techniques, Pregnancy Outcome, Obstetrics and Gynecology, General Medicine, Abortion, medicine.disease, Humans, Medicine, Female, Uterine Cervical Incompetence, Emergencies, Incompetent cervix, business

الوصف: Wurm's technique for correction of an incompetent os during pregnancy is a simple, but not well recognized procedure. In this study, an attempt has been made to evaluate this procedure for elective and emergency cases. Pregnancy outcome of 142 patients who underwent Wurm's operation at the Nehru Hospital, Postgraduate Institute of Medical Education and Research, Chandigarh is presented. Twenty pregnancies resulted in abortion, 47 pregnancies terminated preterm and 75 pregnancies continued beyond 37 weeks. A total of 119 live births yielded a success rate of 83.3%. There were three stillbirths and six infants died during the neonatal period resulting in a fetal salvage of 81%. These results are comparable to those reported for other procedures.

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::40aee8608628840509a6cb2dc637d069Test
https://doi.org/10.1016/0020-7292Test(90)90517-o

المؤلفون: Sarala Gopalan, Lakhbir Kaur Dhaliwal, S. Barik, Arvind Rajwanshi

المصدر: International Journal of Gynecology & Obstetrics. 34:75-77

مصطلحات موضوعية: Ovarian Neoplasms, Accessory ovary, business.industry, medicine.medical_treatment, Ovary, Obstetrics and Gynecology, General Medicine, Anatomy, Middle Aged, medicine.disease, digestive system diseases, Adenocarcinoma, Papillary, medicine.anatomical_structure, Laparotomy, Rare case, medicine, Humans, Adenocarcinoma, Female, Supernumerary ovary, business

الوصف: A rare case of adenocarcinoma of the supernumerary ovary is reported. This rarely encountered gynecological entity posed difficulty in diagnosis and management. However, the behavior is similar to adenocarcinoma of ovary originating from a normal site.

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9c7b27f294c9687ef0cfd9a8e8ed6536Test
https://doi.org/10.1016/0020-7292Test(91)90543-e

المؤلفون: Rashmi Bagga, Lakhbir Kaur Dhaliwal, Indu Gupta, Naveen Kalra, Arvind Rajwanshi

المصدر: Acta Obstetricia et Gynecologica Scandinavica. 83:1095-1096

مصطلحات موضوعية: Vulvar neoplasm, Pathology, medicine.medical_specialty, education.field_of_study, business.industry, Population, Lymphangioma circumscriptum, Obstetrics and Gynecology, Mediastinum, Cystic hygroma, General Medicine, Lymphangiectasia, Anatomy, medicine.disease, body regions, medicine.anatomical_structure, Lymphatic system, Lymphangioma, medicine, business, education

الوصف: Benign tumors of the vulva that are not associated with infectious agents have been classified according to the cell of origin and may be either epithelial or mesenchymal. Among the mesenchymal tumors the vascular tumors include hemangiomas angiokeratomas and lymphangiomas. Simple sustained dilatation of lymphatic vessels is referred to as lymphangiectasia but when lymphatics are distended to tumor-like proportions the term lymphangioma is used. Congenital lymphangiomas are manifestations of vascular malformations of the lymphatic vessels and are classified as lymphangioma circumscriptum cavernous lymphangioma and cystic hygroma. The former presents as a localized group of small gelatinous papulo-vesicular or warty lesions and can occur in the skin throughout the body including the vulva. The latter two are skin-covered swellings that may result in grotesque enlargement of soft tissues are usually solitary and can involve the face trunk and extremities. Cystic hygromas occur commonly in the neck and sometimes in the upper mediastinum. (excerpt)

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_________::4c4c6feadf7b02c1711a987ea409eaa0Test
https://doi.org/10.1111/j.0001-6349.2004.0122d.xTest