التفاصيل البيبلوغرافية
| العنوان: |
Sex differences modulating serotonergic polymorphisms implicated in the mechanistic pathways of risk for depression and related disorders |
| المؤلفون: |
Leanne M. Williams, Andrea N. Goldstein-Piekarski, LeeAnn M. Perry |
| المصدر: |
Journal of Neuroscience Research. 95:737-762 |
| بيانات النشر: |
Wiley, 2016. |
| سنة النشر: |
2016 |
| مصطلحات موضوعية: |
business.industry, media_common.quotation_subject, Early life stress, Bioinformatics, Serotonergic, medicine.disease, Amygdala, 030227 psychiatry, Developmental psychology, 03 medical and health sciences, Cellular and Molecular Neuroscience, 0302 clinical medicine, medicine.anatomical_structure, Conduct disorder, medicine, Personality, Anxiety, medicine.symptom, business, 030217 neurology & neurosurgery, Depression (differential diagnoses), media_common |
| الوصف: |
Despite consistent observations of sex differences in depression and related emotional disorders, we do not yet know how these sex differences modulate the effects of genetic polymorphisms implicated in risk for these disorders. This Mini-Review focuses on genetic polymorphisms of the serotonergic system to illustrate how sex differences might modulate the neurobiological pathways involved in the development of depression. We consider the interacting role of environmental factors such as early-life stress. Given limited current knowledge about this topic, we highlight methodological considerations, challenges, and guidelines for future research. © 2016 Wiley Periodicals, Inc. |
| تدمد: |
0360-4012 |
| الوصول الحر: |
https://explore.openaire.eu/search/publication?articleId=doi_________::6ef5e13b1737c50b8ea1cdda6e65ccd8Test
https://doi.org/10.1002/jnr.23877Test |
| حقوق: |
OPEN |
| رقم الانضمام: |
edsair.doi...........6ef5e13b1737c50b8ea1cdda6e65ccd8 |
| قاعدة البيانات: |
OpenAIRE |
