Eleven New Triterpenoid Glycosides from the Roots of Ilex asprella
العنوان: | Eleven New Triterpenoid Glycosides from the Roots of Ilex asprella |
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المؤلفون: | Wen-Cai Ye, Man-Mei Li, Xiao-Jun Huang, Ying Wang, Qing-Wen Zhang, Si Wen, Zhen-Long Wu, Chun-Lin Fan, Xi-Feng Guan, Ging Chan |
المصدر: | Chemistry & Biodiversity. 16 |
بيانات النشر: | Wiley, 2019. |
سنة النشر: | 2019 |
مصطلحات موضوعية: | Lipopolysaccharides, Phytochemistry, Molecular Conformation, Bioengineering, Microbial Sensitivity Tests, Ilex, Nitric Oxide, Antiviral Agents, Plant Roots, Biochemistry, Mice, Triterpenoid, Ilex asprella, Animals, Glycosides, Molecular Biology, chemistry.chemical_classification, Traditional medicine, Chemistry, Macrophages, Glycoside, General Chemistry, General Medicine, Triterpenes, Respiratory Syncytial Viruses, RAW 264.7 Cells, Molecular Medicine |
الوصف: | Asprellosides A-K, nine new ursane-type triterpenoid glycosides (1-9), and two new oleanane-type triterpenoid glycosides (10 and 11), including six rare sulfated triterpenoid glycosides, were isolated from the roots of Ilex asprella. Their structures were determined on the basis of comprehensive spectroscopic analysis and chemical methods. Among these compounds, asprelloside B (2) and asprelloside C (3) are the first examples of triterpenoid glycosides bearing a rare 3,4-O-disulfo-xylopyranosyl residue. All the saponins isolated showed no significant effects against respiratory syncytial virus (RSV) and lipopolysaccharide-induced nitric oxide production in Raw264.7 macrophages. |
تدمد: | 1612-1880 1612-1872 |
الوصول الحر: | https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bbdaec4774e46ab9bfaba3f82d05620bTest https://doi.org/10.1002/cbdv.201900202Test |
حقوق: | CLOSED |
رقم الانضمام: | edsair.doi.dedup.....bbdaec4774e46ab9bfaba3f82d05620b |
قاعدة البيانات: | OpenAIRE |
تدمد: | 16121880 16121872 |
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