A New Fungal Immunomodulatory Protein, FIP-fve Isolated from the Edible Mushroom, Flammulina velutipes and its Complete Amino Acid Sequence
| العنوان: | A New Fungal Immunomodulatory Protein, FIP-fve Isolated from the Edible Mushroom, Flammulina velutipes and its Complete Amino Acid Sequence |
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| المؤلفون: | Chuan-Liang Kao, Jung-Yaw Lin, Rong-Hwa Lin, Chyong-Ing Hsu, Jiunn-Liang Ko |
| المصدر: | European Journal of Biochemistry. 228:244-249 |
| بيانات النشر: | Wiley, 1995. |
| سنة النشر: | 1995 |
| مصطلحات موضوعية: | Mushroom, Fungal protein, Methionine, biology, Molecular mass, biology.organism_classification, Biochemistry, Edible mushroom, chemistry.chemical_compound, Protein sequencing, chemistry, Peptide sequence, Histidine, Flammulina |
| الوصف: | A new fungal immunomodulatory protein (FIP-fve) has been isolated and purified from the edible golden needle mushroom (Flammulina velutipes). The apparent molecular mass of FIP-fve determined by SDS/PAGE agrees well with the value of 12704 Da calculated from its amino acid composition and sequence. The complete amino acid sequence of FIP-fve was elucidated by protein sequencing techniques. FIP-fve consists of 114 amino acid residues with an acetylated amino end, and lacks methionine, half-cystine and histidine residues. FIP-fve was able to hemagglutinate human red blood cells. The immunomodulatory activity of FIP-fve was demonstrated by its stimulatory activity toward human peripheral blood lymphocytes, and its suppression of systemic anaphylaxis reactions and local swelling of mouse footpads. FIP-fve was found to enhance the transcriptional expression of interleukin-2 and interferon-gamma. |
| تدمد: | 1432-1033 0014-2956 |
| الوصول الحر: | https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dbd866f8d4c181e9614baa865cf4eb39Test https://doi.org/10.1111/j.1432-1033.1995.0244n.xTest |
| حقوق: | CLOSED |
| رقم الانضمام: | edsair.doi.dedup.....dbd866f8d4c181e9614baa865cf4eb39 |
| قاعدة البيانات: | OpenAIRE |
| تدمد: | 14321033 00142956 |
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