نتائج البحث

1

Serum chromogranin A level continuously rises with the progression of type 1 diabetes, and indicates the presence of both enterochromaffin‐like cell hyperplasia and autoimmune gastritis

المؤلفون: Márton Doleschall, Anikó Somogyi, Magdolna Herold, Zoltán Herold, Attila Patócs, Peter Nagy

المصدر: Journal of Diabetes Investigation, Vol 11, Iss 4, Pp 865-873 (2020)
Journal of Diabetes Investigation

مصطلحات موضوعية: 0301 basic medicine, Male, Endocrinology, Diabetes and Metabolism, Neuroendocrine tumors, Gastroenterology, chemistry.chemical_compound, 0302 clinical medicine, Medicine, Prospective Studies, biology, C-Peptide, Glutamate Decarboxylase, Chromogranin A, Enterochromaffin‐like cell hyperplasia, General Medicine, Articles, Hyperplasia, Clinical Science and Care, Autoimmune gastritis, Gastritis, Disease Progression, Biomarker (medicine), Female, Original Article, Adult, medicine.medical_specialty, endocrine system, Enterochromaffin-like Cells, Autoimmune Gastritis, 030209 endocrinology & metabolism, Diseases of the endocrine glands. Clinical endocrinology, Autoimmune Diseases, 03 medical and health sciences, Islets of Langerhans, Internal medicine, Diabetes mellitus, Internal Medicine, Humans, Autoantibodies, Glycated Hemoglobin, Type 1 diabetes, Hungary, business.industry, medicine.disease, RC648-665, 030104 developmental biology, Diabetes Mellitus, Type 1, chemistry, biology.protein, Glycated hemoglobin, business

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::741a714d78d44aaf78f9e4604804fd0eTest
https://doaj.org/article/3dbcf3ebbb9e4c5da1e3b87698b4805eTest

2

Methionine Commits Cells to Differentiate Into Plasmablasts Through Epigenetic Regulation ofBTBandCNCHomolog 2 by the MethyltransferaseEZH2

المؤلفون: Shingo Nakayamada, Masanobu Ueno, Tong Zhang, Mingzeng Zhang, Maiko Hajime, Naoaki Ohkubo, Shigeru Iwata, Hiroko Miyata, Jie Fan, Kaoru Yamagata, Yasuyuki Todoroki, He Hao, Yoshiya Tanaka

المصدر: Arthritis & Rheumatology. 72:1143-1153

مصطلحات موضوعية: Adult, Male, X-Box Binding Protein 1, 0301 basic medicine, Methyltransferase, Plasma Cells, Immunology, B-cell receptor, mTORC1, Mechanistic Target of Rapamycin Complex 1, CD19, Epigenesis, Genetic, 03 medical and health sciences, chemistry.chemical_compound, Methionine, 0302 clinical medicine, Rheumatology, Interferon, medicine, Humans, Lupus Erythematosus, Systemic, Syk Kinase, Immunology and Allergy, Enhancer of Zeste Homolog 2 Protein, Amino Acids, Cells, Cultured, B cell, Autoantibodies, chemistry.chemical_classification, biology, Precursor Cells, B-Lymphoid, Cell Differentiation, Middle Aged, Amino acid, Cell biology, Basic-Leucine Zipper Transcription Factors, 030104 developmental biology, medicine.anatomical_structure, Gene Expression Regulation, chemistry, Case-Control Studies, biology.protein, Female, Positive Regulatory Domain I-Binding Factor 1, 030215 immunology, medicine.drug

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::47f83c76a30bddc46586697dcc78ae03Test
https://doi.org/10.1002/art.41208Test

3

Synergistic effect of ibrutinib and CD19 CAR‐T cells on Raji cells in vivo and in vitro

المؤلفون: Yanyu Jiang, Q Deng, Rui Zhang, Lei Sun, Juan Mu, Meijing Liu, Zheng Li, Xuelin Wang

المصدر: Cancer Science

مصطلحات موضوعية: Male, 0301 basic medicine, Cancer Research, programmed cell death‐ligand 1, T-Lymphocytes, Chronic lymphocytic leukemia, Cell, Immunotherapy, Adoptive, Mice, chemistry.chemical_compound, Basic and Clinical Immunology, Raji cell line, 0302 clinical medicine, Piperidines, hemic and lymphatic diseases, chimeric antigen receptor, medicine.diagnostic_test, biology, Chemistry, General Medicine, Middle Aged, Combined Modality Therapy, Raji cell, Treatment Outcome, medicine.anatomical_structure, Oncology, 030220 oncology & carcinogenesis, Ibrutinib, Original Article, Female, Lymphoma, Large B-Cell, Diffuse, Adult, STAT3 Transcription Factor, Antigens, CD19, Receptors, Antigen, T-Cell, Bruton tyrosine kinase inhibitor, CD19, Immunophenotyping, Flow cytometry, 03 medical and health sciences, In vivo, Cell Line, Tumor, Biomarkers, Tumor, medicine, tumor microenvironment, Animals, Humans, Protein Kinase Inhibitors, Aged, Neoplasm Staging, Tumor microenvironment, Adenine, Original Articles, medicine.disease, Xenograft Model Antitumor Assays, Disease Models, Animal, 030104 developmental biology, biology.protein, Cancer research

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f49d2425f68eed7413004c23fbb5d00bTest
https://doi.org/10.1111/cas.14638Test

4

Characterization of Fibroblasts in Iatrogenic Laryngotracheal Stenosis and Type II Diabetes Mellitus

المؤلفون: Alexander T. Hillel, Ruth J. Davis, Hsiu-Wen Tsai, Kevin M. Motz, Dacheng Ding, Ioan A. Lina

المصدر: Laryngoscope

مصطلحات موضوعية: Male, endocrine system diseases, Biopsy, Iatrogenic Disease, Constriction, Pathologic, Phenformin, Oxidative Phosphorylation, chemistry.chemical_compound, Tracheostomy, 0302 clinical medicine, Myofibroblasts, 030223 otorhinolaryngology, Cells, Cultured, biology, Middle Aged, Metformin, Trachea, medicine.anatomical_structure, 030220 oncology & carcinogenesis, Amobarbital, Female, Tracheal Stenosis, Glycolysis, Myofibroblast, Muscle Contraction, medicine.drug, Adult, Glottis, medicine.medical_specialty, Primary Cell Culture, Article, Contractility, Cicatrix, Young Adult, 03 medical and health sciences, Internal medicine, Intubation, Intratracheal, medicine, Humans, Hypoglycemic Agents, Fibroblast, Aged, Cell Proliferation, business.industry, nutritional and metabolic diseases, Laryngostenosis, Fibronectin, Collagen, type I, alpha 1, Endocrinology, Diabetes Mellitus, Type 2, Otorhinolaryngology, chemistry, Case-Control Studies, biology.protein, Energy Metabolism, business, Ex vivo

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::91d48ca1ac1d15b39afc6fb0f8868387Test
https://doi.org/10.1002/lary.29026Test

5

Hyperuricemia induces lipid disturbances mediated by LPCAT3 upregulation in the liver

المؤلفون: Xiaojuan Yu, Youzhi Xu, Wenjie Lu, Qianqian Sun, Wentong Chen, Jie Jiang, Hu Xu, Ning Liu, Hongquan Wei

المصدر: The FASEB Journal. 34:13474-13493

مصطلحات موضوعية: Adult, Male, STAT3 Transcription Factor, 0301 basic medicine, medicine.medical_specialty, Hyperuricemia, Biochemistry, Mice, 03 medical and health sciences, chemistry.chemical_compound, 0302 clinical medicine, Downregulation and upregulation, In vivo, Internal medicine, Phosphatidylcholine, Lipidomics, Genetics, medicine, Animals, Humans, STAT3, Molecular Biology, Triglycerides, biology, 1-Acylglycerophosphocholine O-Acyltransferase, nutritional and metabolic diseases, Hep G2 Cells, Middle Aged, medicine.disease, In vitro, Uric Acid, Lipoproteins, LDL, Mice, Inbred C57BL, Cholesterol, 030104 developmental biology, Endocrinology, Liver, chemistry, Case-Control Studies, Gene Knockdown Techniques, biology.protein, Uric acid, Female, lipids (amino acids, peptides, and proteins), Sterol Regulatory Element Binding Protein 1, 030217 neurology & neurosurgery, Biotechnology

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f171057dd1544584c4a125b5cd1aed55Test
https://doi.org/10.1096/fj.202000950rTest

6

The benefit of elobixibat in chronic constipation is associated with faecal deoxycholic acid but not effects of altered microbiota

المصدر: Alimentary Pharmacology & Therapeutics. 52:821-828

مصطلحات موضوعية: Adult, Male, medicine.medical_specialty, Organic anion transporter 1, Colon, Thiazepines, medicine.drug_class, Organic Anion Transporters, Sodium-Dependent, Gut flora, digestive system, Gastroenterology, Bile Acids and Salts, Feces, 03 medical and health sciences, chemistry.chemical_compound, fluids and secretions, 0302 clinical medicine, Elobixibat, Internal medicine, medicine, Humans, Pharmacology (medical), Prospective Studies, 030212 general & internal medicine, Defecation, Aged, Chronic constipation, Symporters, Hepatology, biology, Bile acid, business.industry, Microbiota, digestive, oral, and skin physiology, Deoxycholic acid, Dipeptides, Middle Aged, biology.organism_classification, chemistry, Symporter, biology.protein, Female, 030211 gastroenterology & hepatology, business, Constipation, Deoxycholic Acid

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::72f454e52d53ce6a7ce6f339d395141bTest
https://doi.org/10.1111/apt.15950Test

7

Pharmacokinetic Drug Interactions of an Orally Available TRH Analog (Rovatirelin) With a CYP3A4/5 and P‐Glycoprotein Inhibitor (Itraconazole)

المؤلفون: Takuro Endo, Hiroo Takeda, Asuka Kawai, Takao Furihata, Kaoru Kobayashi, Yoshikazu Abe

المصدر: The Journal of Clinical Pharmacology. 60:1314-1323

مصطلحات موضوعية: Adult, Male, Pyrrolidines, Abcg2, Itraconazole, Metabolite, Cmax, Administration, Oral, Drug Elimination Routes, Urine, Pharmacology, 030226 pharmacology & pharmacy, Permeability, Young Adult, 03 medical and health sciences, chemistry.chemical_compound, 0302 clinical medicine, Asian People, Pharmacokinetics, medicine, ATP Binding Cassette Transporter, Subfamily G, Member 2, Cytochrome P-450 CYP3A, Humans, Drug Interactions, Pharmacology (medical), ATP Binding Cassette Transporter, Subfamily B, Member 1, Thyrotropin-Releasing Hormone, Oxazolidinones, biology, CYP3A4, Cytochrome P450, Biological Transport, Healthy Volunteers, Hormones, Neoplasm Proteins, chemistry, Area Under Curve, 030220 oncology & carcinogenesis, biology.protein, Cytochrome P-450 CYP3A Inhibitors, Caco-2 Cells, medicine.drug

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::445b1ecb7c5a250abf7dc69d202fe858Test
https://doi.org/10.1002/jcph.1628Test

8

Pregnancy‐associated venous insufficiency course with placental and systemic oxidative stress

المؤلفون: Julia Buján, Felipe Sainz, Coral Bravo, Clara Martinez-Vivero, Juan De León-Luis, Miguel A Ortega, Natalio García-Honduvilla, Melchor Alvarez-Mon, Beatriz Romero, Ángel Asúnsolo

المصدر: Journal of Cellular and Molecular Medicine

مصطلحات موضوعية: 0301 basic medicine, Placenta, Poly (ADP-Ribose) Polymerase-1, Nitric Oxide Synthase Type II, medicine.disease_cause, chemistry.chemical_compound, 0302 clinical medicine, Pregnancy, Enos, chemistry.chemical_classification, biology, Malondialdehyde, Nitric oxide synthase, ERK, medicine.anatomical_structure, 030220 oncology & carcinogenesis, NOX1, NADPH Oxidase 1, Molecular Medicine, Gestation, Female, Original Article, Poly(ADP-ribose) Polymerases, Adult, malondialdehyde, medicine.medical_specialty, PARP, 03 medical and health sciences, NOX2, Internal medicine, medicine, Humans, Lower extremity venous insufficiency, Reactive oxygen species, business.industry, Pregnancy Complications, Hematologic, inducible nitric oxide synthase, Original Articles, Cell Biology, biology.organism_classification, Oxidative Stress, 030104 developmental biology, Endocrinology, Venous Insufficiency, chemistry, biology.protein, Reactive Oxygen Species, business, Oxidative stress

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::23e85ac5f98fc6025cde6872967913e3Test
https://doi.org/10.1111/jcmm.15077Test

9

Overexpressed microRNA‐103a‐3p inhibits acute lower‐extremity deep venous thrombosis via inhibition of CXCL12

المؤلفون: Shaoliang Sun, Lu Lu, Feng Zhang, Shanyi Chai

المصدر: IUBMB Life. 72:492-504

مصطلحات موضوعية: Adult, Male, 0301 basic medicine, Clinical Biochemistry, Gene Expression, Biochemistry, Mice, 03 medical and health sciences, Thromboxane A2, chemistry.chemical_compound, Tissue factor, 0302 clinical medicine, Von Willebrand factor, Western blot, microRNA, Genetics, Animals, Humans, Medicine, Gene silencing, Stromal cell-derived factor 1, Molecular Biology, Inflammation, Venous Thrombosis, Leg, biology, medicine.diagnostic_test, business.industry, Antagomirs, Extremities, Cell Biology, Middle Aged, Molecular biology, Chemokine CXCL12, Disease Models, Animal, MicroRNAs, 030104 developmental biology, Real-time polymerase chain reaction, chemistry, 030220 oncology & carcinogenesis, biology.protein, Female, business

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e77a7f562ec09dff18b18cd5bfebfd49Test
https://doi.org/10.1002/iub.2168Test

10

Cytokine‐Induced and Stretch‐Induced Sphingosine 1‐Phosphate Production by Enthesis Cells Could Favor Abnormal Ossification in Spondyloarthritis

المؤلفون: David Magne, Anne Briolay, Carole Bougault, Benoit Le Goff, Leyre Brizuela, Frédéric Blanchard, Alaeddine El Jamal, Saida Mebarek

المصدر: Journal of Bone and Mineral Research. 34:2264-2276

مصطلحات موضوعية: Male, 0301 basic medicine, Endocrinology, Diabetes and Metabolism, medicine.medical_treatment, Mice, chemistry.chemical_compound, 0302 clinical medicine, Osteogenesis, Sphingosine, Synovial Fluid, Orthopedics and Sports Medicine, Cells, Cultured, biology, Middle Aged, Up-Regulation, Phosphotransferases (Alcohol Group Acceptor), Receptors, Lysosphingolipid, Cytokine, Sphingosine kinase 1, Cytokines, Female, medicine.symptom, Metabolic Networks and Pathways, Signal Transduction, Adult, medicine.medical_specialty, Adolescent, 030209 endocrinology & metabolism, Inflammation, Young Adult, 03 medical and health sciences, Calcification, Physiologic, Chondrocytes, Internal medicine, Spondylarthritis, medicine, Animals, Humans, Synovial fluid, Sphingosine-1-phosphate, Aged, Osteoblasts, Fingolimod Hydrochloride, Ossification, Enthesis, Tenocytes, 030104 developmental biology, Endocrinology, chemistry, biology.protein, Stress, Mechanical, Lysophospholipids

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2735656fa57700451b4e9985903f8fd5Test
https://doi.org/10.1002/jbmr.3844Test

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