Stenting in Non-Small Cell Lung Cancer: How Does It Affect the Outcomes?
| العنوان: | Stenting in Non-Small Cell Lung Cancer: How Does It Affect the Outcomes? |
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| المؤلفون: | Mahmoud Shehata, Changchun Xie, Ahmed Mostafa, Nagla Abdel Karim, Sadia Benzequene, Sinan Khaddasn, Ihab Eldessouki, Mohamed Magdy |
| المصدر: | Asian Pacific Journal of Cancer Prevention : APJCP |
| بيانات النشر: | West Asia Organization for Cancer Prevention, 2020. |
| سنة النشر: | 2020 |
| مصطلحات موضوعية: | 0301 basic medicine, medicine.medical_specialty, Stenting, Lung Neoplasms, medicine.medical_treatment, 03 medical and health sciences, 0302 clinical medicine, Bronchoscopy, Quality of life, Carcinoma, Non-Small-Cell Lung, Medicine, Humans, Patient group, Lung cancer, non-small cell lung cancer, Retrospective Studies, medicine.diagnostic_test, business.industry, Cancer, Stent, General Medicine, medicine.disease, Interventional pulmonology, Surgery, Airway Obstruction, Survival Rate, lung cancer, 030104 developmental biology, Treatment Outcome, 030220 oncology & carcinogenesis, central airway obstruction, Case-Control Studies, Quality of Life, Stents, Non small cell, business, Research Article, Follow-Up Studies |
| الوصف: | Objective Approximately 30% of lung cancer patients develop central airway obstruction (CAO) that remarkably shortens survival. There is little data about the benefits of stenting within this heterogeneous patient group. Our objective was to review their overall survival (OS) and their risk of hospitalization versus patients who did not have lesions requiring stent placement. Methods We retrospectively reviewed charts of 171 non-small cell lung cancer (NSCLC) patients who underwent bronchoscopy in the University of Cincinnati Cancer Center from the year 2011 to 2013. Twenty-five patients with advanced lung cancer were evaluated by interventional pulmonology service for endobronchial stent placement for CAO. Eight patients did not require placement of a stent and 17 had obstructive lesions that required stenting by interventional pulmonology. Results Demographical parameters such as age and gender did not have a significant impact on the risk of hospitalization or OS of both groups of patients, however, those whose lesions did not mandate stent placement had significantly lower odds of hospitalization compared to patients with CAO requiring a stent (OR: 15.913, 95% CI: 1.211-209.068, P = 0.0352). Patients with advanced NSCLC and CAO that required stent placement had an OS of 13.9 m [3.9-19.9 m] compared to an OS of 23.9 m for patients with CAO not requiring a stent. We found out that patients with less severe CAO have lower odds of hospitalization and better OS compared to patients with CAO mandating stent placement. Conclusion CAO patients with interventional pulmonology (IP) evaluation and management in addition, may have improved OS suggesting that IP consultation might offer both improvement in quality of life and overall survival to patients with advanced NSCLC and CAO. . |
| اللغة: | English |
| تدمد: | 2476-762X 1513-7368 |
| الوصول الحر: | https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b82076cf5b777a87db2dfc4e15ca3732Test http://europepmc.org/articles/PMC7294028Test |
| حقوق: | OPEN |
| رقم الانضمام: | edsair.doi.dedup.....b82076cf5b777a87db2dfc4e15ca3732 |
| قاعدة البيانات: | OpenAIRE |
| تدمد: | 2476762X 15137368 |
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