دورية أكاديمية
Does the difficulty grade of laparoscopic liver resection for colorectal liver metastases correlate with long-term outcomes?
| العنوان: | Does the difficulty grade of laparoscopic liver resection for colorectal liver metastases correlate with long-term outcomes? |
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| المؤلفون: | Hołówko, Wacław, Triantafyllidis, Ioannis, Neuberg, Maud, Tabchouri, Nicolas, Beaussier, Marc, Bennamoun, Mostefa, Sarran, Anthony, Lefevre, Marine, Louvet, Christophe, Gayet, Brice, Fuks, David |
| المصدر: | European Journal of Surgical Oncology, 46 (9), 1620 - 1627 (2020-09) |
| بيانات النشر: | W.B. Saunders Ltd, 2020. |
| سنة النشر: | 2020 |
| مصطلحات موضوعية: | Colorectal liver metastases, Laparoscopic liver resection, Overall survival, Recurrence-free survival, Technical difficulty, Adult, Aged, Aged, 80 and over, Colorectal Neoplasms/pathology, Disease-Free Survival, Female, Humans, Liver Neoplasms/secondary, Liver Neoplasms/surgery, Male, Margins of Excision, Middle Aged, Neoadjuvant Therapy, Prognosis, Retrospective Studies, Survival Rate, Hepatectomy, Laparoscopy, Metastasectomy, Colorectal Neoplasms, Liver Neoplasms, Surgery, Oncology, Human health sciences, Sciences de la santé humaine, Chirurgie |
| الوصف: | [en] INTRODUCTION: Prognosis of patients with colorectal liver metastases (CRLM) is strongly correlated with the oncological outcome after liver resection. The aim of this study was to analyze the impact of laparoscopic liver resection (LLR) difficulty score (IMM difficulty score) on the oncological results in patients treated for CRLM.METHODS: All patients who underwent LLRs for CRLM from 2000 to 2016 in our department, were retrospectively reviewed. Data regarding difficulty classification, -according to the Institute Mutualiste Montsouris score (IMM)-, recurrence rate, recurrence-free survival (RFS), overall survival (OS) and data regarding margin status were analyzed.RESULTS: A total of 520 patients were included. Patients were allocated into 3 groups based on IMM difficulty score of the LLR they underwent: there were 227 (43,6%), 84 (16,2%) and 209 (40,2%) patients in groups I, II and III, respectively. The R1 resection rate in group I, II and III were 8,8% (20/227), 11,9% (10/84) and 12,4% (26/209) respectively (p = 0.841). Three- and 5-year RFS rates were 77% and 73% in group I, 58% and 51% in group II, 61% and 53% in group III, respectively (p = 0.038). Three and 5-year OS rates were 87% and 80% for group I, 77% and 66% for group II, 80% and 69% for group III respectively (p = 0.022).CONCLUSION: The higher LLR difficulty score correlates with significant morbidity and worse RFS and OS, although the more technically demanding and difficult cases are not associated with increased rates of positive resection margins and recurrence. |
| نوع الوثيقة: | journal article http://purl.org/coar/resource_type/c_6501Test article peer reviewed |
| اللغة: | English |
| العلاقة: | https://api.elsevier.com/content/article/PII:S0748798320304923?httpAccept=text/xmlTest; urn:issn:0748-7983; urn:issn:1532-2157 |
| DOI: | 10.1016/j.ejso.2020.05.019 |
| الوصول الحر: | https://orbi.uliege.be/handle/2268/317021Test |
| حقوق: | open access http://purl.org/coar/access_right/c_abf2Test info:eu-repo/semantics/openAccess |
| رقم الانضمام: | edsorb.317021 |
| قاعدة البيانات: | ORBi |
| DOI: | 10.1016/j.ejso.2020.05.019 |
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