دورية أكاديمية
Association between ventilatory settings and development of acute respiratory distress syndrome in mechanically ventilated patients due to brain injury
| العنوان: | Association between ventilatory settings and development of acute respiratory distress syndrome in mechanically ventilated patients due to brain injury |
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| المؤلفون: | Tejerina, Eva, Pelosi, Paolo, Muriel, Alfonso, Peñuelas, Oscar, Sutherasan, Yuda, Frutos-Vivar, Fernando, Nin, Nicolás, Davies, Andrew R., Rios, Fernando, Violi, Damian A., Raymondos, Konstantinos, Hurtado, Javier, González, Marco, Du, Bin, Amin, Pravin, Maggiore, Salvatore M., Thille, Arnaud W., Soares, Marco Antonio, Jibaja, Manuel, Villagomez, Asisclo J., Kuiper, Michael A., Koh, Younsuck, Moreno, Rui P., Zeggwagh, Amine Ali, Matamis, Dimitrios, Anzueto, Antonio, Ferguson, Niall D., Esteban, Andrés |
| المساهمون: | Tejerina, Eva, Pelosi, Paolo, Muriel, Alfonso, Peñuelas, Oscar, Sutherasan, Yuda, Frutos-Vivar, Fernando, Nin, Nicolá, Davies, Andrew R., Rios, Fernando, Violi, Damian A., Raymondos, Konstantino, Hurtado, Javier, González, Marco, Du, Bin, Amin, Pravin, Maggiore, Salvatore M., Thille, Arnaud W., Soares, Marco Antonio, Jibaja, Manuel, Villagomez, Asisclo J., Kuiper, Michael A., Koh, Younsuck, Moreno, Rui P., Zeggwagh, Amine Ali, Matamis, Dimitrio, Anzueto, Antonio, Ferguson, Niall D., Esteban, Andrés |
| بيانات النشر: | W.B. Saunders |
| سنة النشر: | 2017 |
| المجموعة: | Università degli Studi di Genova: CINECA IRIS |
| مصطلحات موضوعية: | Acute respiratory distress syndrome, Driving pressure, Mechanical ventilation, Neurologic disease, Neurologically critically ill patient, Pulmonary complication, Adult, Aged, Brain Injurie, Critical Illne, Female, Glasgow Coma Scale, Human, Incidence, Intensive Care Unit, Length of Stay, Male, Middle Aged, Morbidity, Mortality, Multivariate Analysi, Pressure, Prospective Studie, Respiration, Artificial, Respiratory Distress Syndrome, Risk Factor, Time Factor, Positive-Pressure Respiration, Tidal Volume |
| الوصف: | Purpose In neurologically critically ill patients with mechanical ventilation (MV), the development of acute respiratory distress syndrome (ARDS) is a major contributor to morbidity and mortality, but the role of ventilatory management has been scarcely evaluated. We evaluate the association of tidal volume, level of PEEP and driving pressure with the development of ARDS in a population of patients with brain injury. Materials and methods We performed a secondary analysis of a prospective, observational study on mechanical ventilation. Results We included 986 patients mechanically ventilated due to an acute brain injury (hemorrhagic stroke, ischemic stroke or brain trauma). Incidence of ARDS in this cohort was 3%. Multivariate analysis suggested that driving pressure could be associated with the development of ARDS (odds ratio for unit increment of driving pressure 1.12; confidence interval for 95%: 1.01 to 1.23) whereas we did not observe association for tidal volume (in ml per kg of predicted body weight) or level of PEEP. ARDS was associated with an increase in mortality, longer duration of mechanical ventilation, and longer ICU length of stay. Conclusions In a cohort of brain-injured patients the development of ARDS was not common. Driving pressure was associated with the development of this disease. |
| نوع الوثيقة: | article in journal/newspaper |
| وصف الملف: | ELETTRONICO |
| اللغة: | English |
| العلاقة: | info:eu-repo/semantics/altIdentifier/pmid/27914908; info:eu-repo/semantics/altIdentifier/wos/WOS:000401100300059; volume:38; firstpage:341; lastpage:345; numberofpages:5; journal:JOURNAL OF CRITICAL CARE; http://hdl.handle.net/11567/945054Test; info:eu-repo/semantics/altIdentifier/scopus/2-s2.0-85007433809 |
| DOI: | 10.1016/j.jcrc.2016.11.010 |
| الإتاحة: | https://doi.org/10.1016/j.jcrc.2016.11.010Test http://hdl.handle.net/11567/945054Test |
| رقم الانضمام: | edsbas.E7B044C3 |
| قاعدة البيانات: | BASE |
| DOI: | 10.1016/j.jcrc.2016.11.010 |
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