Superimposed Coagulopathic Conditions in Cirrhosis: Infection and Endogenous Heparinoids, Renal Failure, and Endothelial Dysfunction
| العنوان: | Superimposed Coagulopathic Conditions in Cirrhosis: Infection and Endogenous Heparinoids, Renal Failure, and Endothelial Dysfunction |
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| المؤلفون: | Frank W.G. Leebeek, Jasper H. Smalberg |
| المساهمون: | Hematology |
| المصدر: | Clinics in Liver Disease, 13(1), 33-+. W.B. Saunders |
| بيانات النشر: | W.B. Saunders, 2009. |
| سنة النشر: | 2009 |
| مصطلحات موضوعية: | Liver Cirrhosis, medicine.medical_specialty, Cirrhosis, Gastroenterology, Varicose Veins, Liver disease, Von Willebrand factor, Internal medicine, von Willebrand Factor, medicine, Humans, Renal Insufficiency, Endothelial dysfunction, Heparinoids, Blood Coagulation, Endothelin-1, Hepatology, biology, business.industry, Bacterial Infections, Blood Coagulation Disorders, medicine.disease, Pathophysiology, Coagulation, Hemostasis, biology.protein, Endothelium, Vascular, business, Biomarkers |
| الوصف: | In this article, the authors discuss three pathophysiologic mechanisms that influence the coagulation system in patients who have liver disease. First, bacterial infections may play an important role in the cause of variceal bleeding in patients who have liver cirrhosis, affecting coagulation through multiple pathways. One of the pathways through which this occurs is dependent on endogenous heparinoids, on which the authors focus in this article. Secondly, the authors discuss renal failure, a condition that is frequently encountered in patients who have liver cirrhosis. Finally, they review dysfunction of the endothelial system. The role of markers of endothelial function in cirrhotic patients, such as von Willebrand factor and endothelin-1, is discussed. |
| تدمد: | 1557-8224 1089-3261 |
| الوصول الحر: | https://explore.openaire.eu/search/publication?articleId=doi_dedup___::789337aee4a69d361a61e9077f76136cTest https://pure.eur.nl/en/publications/9b7dfeaa-0b30-4218-92b6-c85412bbb7feTest |
| حقوق: | RESTRICTED |
| رقم الانضمام: | edsair.doi.dedup.....789337aee4a69d361a61e9077f76136c |
| قاعدة البيانات: | OpenAIRE |
| تدمد: | 15578224 10893261 |
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