دورية أكاديمية
Effect of statin therapy on cancer incidence
| العنوان: | Effect of statin therapy on cancer incidence |
|---|---|
| المؤلفون: | Marko Skelin, Eugen Javor, Vesna Pavlica, Ljubica Pavela, Marina Matković, Robert Šeparović |
| المصدر: | Endocrine Oncology and Metabolism, Vol 2, Iss 4, Pp 250-257 (2016) |
| بيانات النشر: | VBZ |
| سنة النشر: | 2016 |
| المجموعة: | Directory of Open Access Journals: DOAJ Articles |
| مصطلحات موضوعية: | statin, simvastatin, therapy, cancer, incidence, Neoplasms. Tumors. Oncology. Including cancer and carcinogens, RC254-282 |
| الوصف: | Statins, as lipid lowering agents have a well-established role in the primary and secondary prevention of cardiovascular (CV) events. They are one of the most prescribed medicines worldwide. Lipidlowering drugs have been implicated in rodent carcinogenicity and concerns about the same effect in humans have been raised. Low plasma cholesterol levels has been associated with an increased risk of cancer and a possible reason for this observation could be related to the presence subclinical disease, where subclinical disease lowered cholesterol levels for years before cancer surfaced clinically. Many papers have discussed the possible mechanisms leading to the increased cancer incidence in statin users, but the results have been controversial and inconclusive. The aim of this paper is to present and evaluate the latest evidence regarding statin use on cancer incidence. |
| نوع الوثيقة: | article in journal/newspaper |
| اللغة: | English |
| تدمد: | 1849-8922 1849-9031 |
| العلاقة: | http://eom.hdeo.eu/wp-content/uploads/2016/12/vol2-iss4-4skelin.pdfTest; https://doaj.org/toc/1849-8922Test; https://doaj.org/toc/1849-9031Test; https://doaj.org/article/707b8bed649c4c2d9a08af7bfe24c082Test |
| DOI: | 10.21040/eom/2016.2.4.2 |
| الإتاحة: | https://doi.org/10.21040/eom/2016.2.4.2Test https://doaj.org/article/707b8bed649c4c2d9a08af7bfe24c082Test |
| رقم الانضمام: | edsbas.4309ABE1 |
| قاعدة البيانات: | BASE |
| تدمد: | 18498922 18499031 |
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| DOI: | 10.21040/eom/2016.2.4.2 |