رسالة جامعية
Analysis of Human Biological Monitoring Data for Polyhalogenated Organophosphate Flame Retardants
| العنوان: | Analysis of Human Biological Monitoring Data for Polyhalogenated Organophosphate Flame Retardants |
|---|---|
| المؤلفون: | Phipps, Hannah |
| بيانات النشر: | University of Cincinnati / OhioLINK, 2023. |
| سنة النشر: | 2023 |
| المجموعة: | Ohiolink ETDs |
| Original Material: | http://rave.ohiolink.edu/etdc/view?acc_num=ucin1684772237956658Test |
| مصطلحات موضوعية: | Environmental Science, Fractional Urinary Excretion FUE, Reverse Dosimetry, Internal Dose |
| الوصف: | Humans can be exposed to hazardous chemicals through the three main routes of exposure which are inhalation, ingestion, and dermal. The hand – to – mouth behavior in infants and toddlers is a common route of exposure due to infants’ and toddlers’ exploratory behavior. Exposures to hazardous chemicals can be measured by biomonitoring. Biomonitoring measure the total exposure at an individual level from all exposure routes and sources. With the infant’s exploratory behavior, primarily from the infants crawling, we asked whether infant internal doses of polyhalogenated organophosphate (PHOP) flame retardants are higher than the doses found in adults. The project identified human biomonitoring data for PHOPS from published articles. The three main polyhalogenated organophosphate flame retardants were: tris (1-chloro – 2 – propyl) phosphate, tris (2 – chloroethyl) phosphate, and tris (1, 3 – dichloroisopropyl) phosphate). A total of four hundred and seven published data articles were initially reviewed by the team for screening. For the light extraction, two hundred and ninety-nine published data articles were screened. Out of the two hundred and ninety-nine articles a total of one hundred and thirty were screened for this master’s thesis, and reverse dosimetry was conducted on five articles with data on children or other potential highly exposed groups. The internal dose of PHOPS were calculated by applying reverse dosimetry to the concentrations in the human urine. We currently, do not have enough evidence to determine whether infants have a higher internal dose than adults. The results indicate that further investigation on infant and adult internal doses of PHOPS is needed. |
| Original Identifier: | oai:etd.ohiolink.edu:ucin1684772237956658 |
| نوع الوثيقة: | Text |
| اللغة: | English |
| الإتاحة: | http://rave.ohiolink.edu/etdc/view?acc_num=ucin1684772237956658Test |
| حقوق: | unrestricted This thesis or dissertation is protected by copyright: some rights reserved. It is licensed for use under a Creative Commons license. Specific terms and permissions are available from this document's record in the OhioLINK ETD Center. |
| رقم الانضمام: | edsndl.OhioLink.oai.etd.ohiolink.edu.ucin1684772237956658 |
| قاعدة البيانات: | Networked Digital Library of Theses & Dissertations |
| الوصف غير متاح. |