رسالة جامعية
Blood Glucose Variability in Relation to Eating Frequency, Composition, and Meal Size in Adolescents with Type 1 Diabetes Following a DASH Dietary Pattern
| العنوان: | Blood Glucose Variability in Relation to Eating Frequency, Composition, and Meal Size in Adolescents with Type 1 Diabetes Following a DASH Dietary Pattern |
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| المؤلفون: | Maco, Kimberly |
| بيانات النشر: | University of Cincinnati / OhioLINK, 2016. |
| سنة النشر: | 2016 |
| المجموعة: | Ohiolink ETDs |
| Original Material: | http://rave.ohiolink.edu/etdc/view?acc_num=ucin1470753751Test |
| مصطلحات موضوعية: | Nutrition, DASH diet, meal patterning, glycemic variability, meal frequency, meal composition, meal size |
| الوصف: | Background: Glycemic variability (GV) is a contributor to cardiovascular disease (CVD) and related to complications in individuals with type 1 diabetes mellitus (T1DM). Research suggests that GV may be reduced through increased frequency of eating occasions and increased intake of soluble fiber, protein and fat at meals; this dietary composition aligns well with the Dietary Approaches to Stop Hypertension (DASH) diet recommendations. Objective: The objective of this study was to determine whether GV of adolescents with T1DM using continuous insulin infusion was related to the composition, size, and frequency of eating occasions when following a diet compliant with the DASH dietary pattern or their usual intake. Methods: Nine adolescent patients (10-17 years of age), both male and female, with T1DM consumed their usual diet (based on carbohydrate (CHO) counting) and then a diet compliant with the DASH dietary pattern while wearing a continuous glucose monitoring (CGM) system for 3 days each. A DASH diet prescription was determined for each patient and meals were designed to comply with these specifications. Dietary components (i.e. macronutrient composition and quantity, total and dietary fiber, and energy), eating occasion frequency (total number of eating occasions), and CGM data of each 3-day period were assessed. Each dietary component variable was calculated as the average of all eating occasions during the study period. CGM data measured the temporal glucose fluctuations at 5-minute increments. GV, calculated from the CGM data, was determined based on established metrics: continuous overlapping net glycemic action (CONGA), standard deviation (SDt), and index of glycemic action (IGC). Confounding variables included in the statistical analysis were age, BMI percent, and HbA1c. Results: Glycemic variability, during the DASH diet period only, was inversely related to total dietary fiber (SDt, (ß=-69.84, p=0.024) and CONGA (ß=-1.56, p=0.09)) and soluble fiber (CONGA (ß=-3.31, p=0.031); SDt (ß=-127.28, p=0.045); IGC (ß=-3.14, p=0.092)). Additionally, GV, during the DASH diet period only, was inversely related to percent fat of eating occasions (CONGA (ß=-0.176, p=0.02); IGC (ß=-0.217, p=0.078); SDt (ß=- 5.49, p=0.013)), and showed a positive trend with percent carbohydrate of eating occasions (CONGA (ß=0.141, p=0.053); IGC (ß=0.197, p=0.061); SDt (ß=3.909, p=0.096)). As expected, total and soluble fiber intakes were higher on the DASH diet compared to the usual intake period (p |
| Original Identifier: | oai:etd.ohiolink.edu:ucin1470753751 |
| نوع الوثيقة: | text |
| اللغة: | English |
| الإتاحة: | http://rave.ohiolink.edu/etdc/view?acc_num=ucin1470753751Test |
| حقوق: | unrestricted This thesis or dissertation is protected by copyright: all rights reserved. It may not be copied or redistributed beyond the terms of applicable copyright laws. |
| رقم الانضمام: | edsndl.OhioLink.oai.etd.ohiolink.edu.ucin1470753751 |
| قاعدة البيانات: | Networked Digital Library of Theses & Dissertations |
| الوصف غير متاح. |