دورية أكاديمية
The Effect of CaCl2 Added PRP (Platelet Rich Plasma) to the Healing Time, Tensile Strength and Adhesion Degree of the Ruptured Tendinopathic Achilles Tendon of Rats (Rattus norvegicus)
| العنوان: | The Effect of CaCl2 Added PRP (Platelet Rich Plasma) to the Healing Time, Tensile Strength and Adhesion Degree of the Ruptured Tendinopathic Achilles Tendon of Rats (Rattus norvegicus) |
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| المؤلفون: | Istan Irmansyah Irsan, R. Muhammad David Jayanegara |
| المصدر: | Berkala Kedokteran, Vol 15, Iss 1, Pp 59-70 (2019) |
| بيانات النشر: | Universitas Lambung Mangkurat, 2019. |
| سنة النشر: | 2019 |
| المجموعة: | LCC:Medicine (General) |
| مصطلحات موضوعية: | berkala kedokteran, achilles tendinopathy, prp, healing time, tensile strength, adhesion, Medicine (General), R5-920 |
| الوصف: | Abstract: Achilles tendinopathy produce morbidity, long-lasting disability in athletes and non-athletes and remain a challenge for clinician. Tendinopathy may lead to reduced tensile strength and a predisposition to rupture.The aim of our study was to evaluate the effects of activated and non-activated PRP on the healing process of ruptured tendinopathic achilles tendon in rat. Tendinopathy achilles condition induced by injecting collagenase bacterial type-1 locally. Right achilles tendon in 48 rats ruptured by transecting it transversely and repaired it by using a Kessler technique. Further, the wound immobilized with PRP and injecting activated PRP (5% CaCl2 added) in one group, non-activated PRP on the other group and saline on control group. Tendons from each group were collected at the 1st and 2nd week postoperatively also assessed for biomechanical test. Tendons were also evaluated histologically by using hematoxylin-eosin to know adhesion degree based on Tang criteria. The significant differences was found between intervention group and control (p0.05). Adhesion degree of the intervention group also reduce better rather than the control at the 1st and 2nd week (p |
| نوع الوثيقة: | article |
| وصف الملف: | electronic resource |
| اللغة: | English Indonesian |
| تدمد: | 1412-0550 2548-5660 |
| العلاقة: | https://ppjp.ulm.ac.id/journal/index.php/jbk/article/view/6123Test; https://doaj.org/toc/1412-0550Test; https://doaj.org/toc/2548-5660Test |
| DOI: | 10.20527/jbk.v15i1.6123 |
| الوصول الحر: | https://doaj.org/article/c142c3b1b33c4637b7bdc9246a664b53Test |
| رقم الانضمام: | edsdoj.142c3b1b33c4637b7bdc9246a664b53 |
| قاعدة البيانات: | Directory of Open Access Journals |
| تدمد: | 14120550 25485660 |
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| DOI: | 10.20527/jbk.v15i1.6123 |