Performance of Tween 80 as Surfactant for Chitosan Drug Delivery Film
| العنوان: | Performance of Tween 80 as Surfactant for Chitosan Drug Delivery Film |
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| المؤلفون: | Maharani Kusumaningrum, Nadya Alfa Cahaya Imani |
| المصدر: | CHEMICA: Jurnal Teknik Kimia. 6:77 |
| بيانات النشر: | Universitas Ahmad Dahlan, 2019. |
| سنة النشر: | 2019 |
| مصطلحات موضوعية: | Chitosan, Zero order, chemistry.chemical_compound, chemistry, Pulmonary surfactant, Chemical engineering, Low molecular weight chitosan, Drug delivery, Kinetics, Drug release, General Medicine |
| الوصف: | Optimization of the drug delivery system is based on the need for more efficient and effective drugs to fight disease. The addition of surfactant as an additive in the drug delivery precursor solution can affect the performance of the material, especially on the ability of drug release. In this study, Tween 80 was used as a surfactant to be mixed in a low molecular weight chitosan solution. Several variations of the Tween 80: chitosan ratios, as well as variations in acidity conditions, are used to determine the optimum conditions for drug release. Drug release profile fittings were tested on three kinetic models that were frequently used namely zero order model, Higuchi’s model, and Korsmeyer-Peppa’s model. The results showed that the optimum conditions for release were obtained with the use of a ratio of 7:10 with a release profile resembling Korsmeyer-Peppa’s model. |
| تدمد: | 2355-8776 2355-875X |
| الوصول الحر: | https://explore.openaire.eu/search/publication?articleId=doi_________::4cd48ac46b73a439982b0a32fa352e9fTest https://doi.org/10.26555/chemica.v6i2.14792Test |
| حقوق: | OPEN |
| رقم الانضمام: | edsair.doi...........4cd48ac46b73a439982b0a32fa352e9f |
| قاعدة البيانات: | OpenAIRE |
| تدمد: | 23558776 2355875X |
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